Hyattsville, Maryland Clinical Trials

A listing of Hyattsville, Maryland clinical trials actively recruiting patient volunteers.

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Found 230 clinical trials
A Study to Assess Whether Macitentan Delays Disease Progression in Children With Pulmonary Arterial Hypertension (PAH)

This is a prospective, multicenter, open-label, randomized, controlled, parallel group, group-sequential, event-driven Phase 3 study to evaluate efficacy, safety and pharmacokinetics (PK) of macitentan in children.

hypertension
macitentan
connective tissue disease
heart disease
Children's National Medical Center
 (5.4 away) Contact site
  • 172 views
  • 04 Nov, 2020
  • +104 other locations
A Study of Bendamustine and Rituximab Alone Versus in Combination With Acalabrutinib in Subjects With Previously Untreated Mantle Cell Lymphoma

This study is evaluating the efficacy of acalabrutinib in combination with bendamustine and rituximab (BR) compared with placebo plus BR in subjects with previously untreated mantle cell lymphoma.

rituximab
acalabrutinib
cyclin d1
bendamustine
Research Site
 (7.8 away) Contact site
  • 1270 views
  • 30 Jul, 2020
  • +212 other locations
Effect of Tumor Treating Fields (TTFields) (150 kHz) Concurrent With Standard of Care Therapies for Treatment of Stage 4 Non-small Cell Lung Cancer (NSCLC) Following Platinum Failure (LUNAR)

The study is a prospective, randomized controlled phase III trial aimed to test the efficacy and safety of TTFields, using the NovoTTF-100L System, concurrent with standard therapies for stage 4 NSCLC patients, following progression while on or after platinum based treatment.The device is an experimental, portable, battery operated device for …

docetaxel
Washington Cancer Institute at MedStar Washington Hospital Center
 (5.4 away) Contact site
  • 644 views
  • 19 Oct, 2020
  • +164 other locations
A Study of Androgen Annihilation in High-Risk Biochemically Relapsed Prostate Cancer

This is a randomized, open-label, three-arm, phase 3 study in men with biochemically recurrent prostate cancer and PSA doubling time 9 months at the time of study entry.

abiraterone
androgens
adenocarcinoma
metastasis
choline
Georgetown University Medical Center
 (7.8 away) Contact site
  • 496 views
  • 03 Jun, 2019
  • +67 other locations
Immunogenicity and Safety of a Quadrivalent Meningococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers in the US

The purpose of this study is to compare the immunogenicity and describe the safety of MenACYW conjugate vaccine and MENVEO when both are administered concomitantly with routine pediatric vaccines to healthy infants and toddlers in the US. Primary objectives: To demonstrate the non-inferiority of the immune response after a 4-dose …

mumps
rubella
meningococcal conjugate
menveo
rotavirus
Investigational Site Number 8400041
 (6.2 away) Contact site
  • 501 views
  • 21 Sep, 2020
  • +82 other locations
Linaclotide Safety and Efficacy Functional Constipation in Pediatric Participants 6 to 17 Years of Age

The purpose of this study is to evaluate the safety, tolerability and efficacy of 12 weeks of linaclotide therapy in comparison with placebo in pediatric participants aged 6 to 17 years who fulfill modified Rome III Criteria for Child/Adolescent.

incontinence
laxative
posturing
Children's National Medical Center
 (5.3 away) Contact site
  • 136 views
  • 08 Oct, 2020
  • +146 other locations
A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-Small Cell Lung Cancer

The purpose of this study is to assess the efficacy of the amivantamab and lazertinib combination, compared with osimertinib, in participants with epidermal growth factor receptor (EGFR) mutation (Exon 19 deletions [Exon 19del] or Exon 21 L858R substitution) positive, locally advanced or metastatic non-small cell lung cancer (NSCLC).

epidermal growth factor receptor
cancer treatment
lung carcinoma
osimertinib
measurable disease
Inje University Haeundae Paik Hospital
 (6.9 away) Contact site
  • 27 views
  • 23 Nov, 2020
  • +268 other locations
A Study of Combination Amivantamab and Carboplatin-Pemetrexed Therapy Compared With Carboplatin-Pemetrexed in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Characterized by Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions

The purpose of this study is to compare the efficacy, as demonstrated by progression-free survival (PFS), in participants treated with amivantamab in combination with chemotherapy, versus chemotherapy alone in participants with locally advanced or metastatic non-small cell lung cancer (NSCLC) characterized by EGFR Exon 20ins mutations.

Georgetown University Hospital
 (7.9 away) Contact site
  • 0 views
  • 11 Nov, 2020
  • +215 other locations
A Study to Assess the Efficacy and Safety of Nemolizumab (CD14152) in Participants With Prurigo Nodularis (PN)

The primary objective is to assess the efficacy of nemolizumab (CD14152) compared to placebo in participants greater than or equal to (>=) 18 years of age with prurigo nodularis (PN) after a 16-week treatment period.

Galderma Investigational Site
 (7.1 away) Contact site
  • 0 views
  • 22 Nov, 2020
  • +62 other locations
A Phase 3 Study to Evaluate the Efficacy and Safety of Benralizumab in Patients With Hypereosinophilic Syndrome (HES)

This is a multicentre, randomised, double-blind (DB), parallel-group, placebo-controlled, 24-week Phase 3 study to compare the efficacy and safety of benralizumab versus placebo administered by SC injection Q4W in patients with hypereosinophilic syndrome (HES). This study comprises 2 distinct periods (together defined as the 'main study'): A 24-week, DB treatment …

Research Site
 (9.4 away) Contact site
  • 0 views
  • 04 Nov, 2020
  • +37 other locations