Hyattsville, Maryland Clinical Trials

A listing of Hyattsville, Maryland clinical trials actively recruiting patient volunteers.

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Found 233 clinical trials
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A Study to Evaluate the Efficacy and Safety of Pemigatinib Versus Chemotherapy in Unresectable or Metastatic Cholangiocarcinoma - (FIGHT-302)

The purpose of this study is to evaluate the efficacy and safety of pemigatinib versus gemcitabine plus cisplatin chemotherapy in first-line treatment of participants with unresectable or metastatic cholangiocarcinoma with FGFR2 rearrangement.  

Georgetown University Hospital
 (7.9 away) Contact site
  • 154 views
  • 23 Nov, 2020
  • +154 other locations
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ECOSPOR IV: An Open-Label Extension of Study SERES-012 and Open-Label Program for Evaluating SER-109 in Adult Subjects with Recurrent Clostridioides difficile Infection (RCDI)

ECOSPOR IV is a Phase 3, multicenter, Open Label study to evaluate the safety and tolerability of SER-109 in adult subjects with recurrent CDI.

Metropolitan Gastroenterology Group, PC - Chevy Chase Clinical Research
 (8.1 away) Contact site
  • 37 views
  • 23 Nov, 2020
  • +76 other locations
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A Phase III study of the Efficacy and Safety of subjects with Moderately to Severe active Rheumatoid Arthritis which have been inadequately controlled by Tumor Necrosis Factor Alpha (TNF-a) inhibitor therapy

A Phase III study of the Efficacy and Safety of subjects with Moderately to Severe active Rheumatoid Arthritis which have been inadequately controlled by Tumor Necrosis Factor Alpha (TNF-a) inhibitor therapy

The Center for Rheumatology and Bone Research
 (8.5 away) Contact site
  • 302 views
  • 08 Nov, 2020
  • 1 location
A Study to Assess Whether Macitentan Delays Disease Progression in Children With Pulmonary Arterial Hypertension (PAH)

This is a prospective, multicenter, open-label, randomized, controlled, parallel group, group-sequential, event-driven Phase 3 study to evaluate efficacy, safety and pharmacokinetics (PK) of macitentan in children.

heart disease
connective tissue disease
hypertension
macitentan
Children's National Medical Center
 (5.4 away) Contact site
  • 172 views
  • 04 Nov, 2020
  • +104 other locations
A Study of Bendamustine and Rituximab Alone Versus in Combination With Acalabrutinib in Subjects With Previously Untreated Mantle Cell Lymphoma

This study is evaluating the efficacy of acalabrutinib in combination with bendamustine and rituximab (BR) compared with placebo plus BR in subjects with previously untreated mantle cell lymphoma.

acalabrutinib
bendamustine
rituximab
cyclin d1
Research Site
 (7.8 away) Contact site
  • 1270 views
  • 30 Jul, 2020
  • +212 other locations
Effect of Tumor Treating Fields (TTFields) (150 kHz) Concurrent With Standard of Care Therapies for Treatment of Stage 4 Non-small Cell Lung Cancer (NSCLC) Following Platinum Failure (LUNAR)

The study is a prospective, randomized controlled phase III trial aimed to test the efficacy and safety of TTFields, using the NovoTTF-100L System, concurrent with standard therapies for stage 4 NSCLC patients, following progression while on or after platinum based treatment.The device is an experimental, portable, battery operated device for …

docetaxel
Washington Cancer Institute at MedStar Washington Hospital Center
 (5.4 away) Contact site
  • 644 views
  • 19 Oct, 2020
  • +164 other locations
A Study of Androgen Annihilation in High-Risk Biochemically Relapsed Prostate Cancer

This is a randomized, open-label, three-arm, phase 3 study in men with biochemically recurrent prostate cancer and PSA doubling time 9 months at the time of study entry.

adenocarcinoma of prostate
prostatectomy
apalutamide
luteinizing hormone-releasing hormone agonist
bone scan
Georgetown University Medical Center
 (7.8 away) Contact site
  • 496 views
  • 03 Jun, 2019
  • +67 other locations
Immunogenicity and Safety of a Quadrivalent Meningococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers in the US

The purpose of this study is to compare the immunogenicity and describe the safety of MenACYW conjugate vaccine and MENVEO when both are administered concomitantly with routine pediatric vaccines to healthy infants and toddlers in the US. Primary objectives: To demonstrate the non-inferiority of the immune response after a 4-dose …

mumps
hepatitis a vaccine
varicella vaccine
dtap
conjugate vaccine
Investigational Site Number 8400041
 (6.2 away) Contact site
  • 501 views
  • 21 Sep, 2020
  • +82 other locations
Linaclotide Safety and Efficacy Functional Constipation in Pediatric Participants 6 to 17 Years of Age

The purpose of this study is to evaluate the safety, tolerability and efficacy of 12 weeks of linaclotide therapy in comparison with placebo in pediatric participants aged 6 to 17 years who fulfill modified Rome III Criteria for Child/Adolescent.

incontinence
posturing
laxative
Children's National Medical Center
 (5.3 away) Contact site
  • 136 views
  • 08 Oct, 2020
  • +146 other locations
A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-Small Cell Lung Cancer

The purpose of this study is to assess the efficacy of the amivantamab and lazertinib combination, compared with osimertinib, in participants with epidermal growth factor receptor (EGFR) mutation (Exon 19 deletions [Exon 19del] or Exon 21 L858R substitution) positive, locally advanced or metastatic non-small cell lung cancer (NSCLC).

EGFR
solid tumour
osimertinib
lung carcinoma
measurable disease
Inje University Haeundae Paik Hospital
 (6.9 away) Contact site
  • 27 views
  • 23 Nov, 2020
  • +268 other locations