Hyattsville, Maryland Clinical Trials

A listing of Hyattsville, Maryland clinical trials actively recruiting patient volunteers.

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Found 309 clinical trials
A Study of INCMGA00012 in Metastatic Merkel Cell Carcinoma (POD1UM-201)

The purpose of this study is to assess the clinical activity and safety of INCMGA00012 in participants with advanced/metastatic Merkel cell carcinoma (MCC).

Georgetown University - Lombardi Comprehensive Cancer Center
 (7.9 away) Contact site
  • 21 views
  • 11 Nov, 2020
  • +74 other locations
Safety Study of Unlicensed Investigational Cord Blood Units Manufactured by the NCBP for Unrelated Transplantation

This study will evaluate the safety of infusion of the investigational cord blood units by carefully documenting all infusion-related problems.

Children's National Medical Center
 (5.4 away) Contact site
  • 239 views
  • 21 Jun, 2020
  • +61 other locations
Vinblastine +/- Bevacizumab in Children With Unresectable or Progressive Low Grade Glioma (LGG)

This is an open-label, randomized, multi-center, comparator Phase II trial looking at the addition of Bevacizumab to Vinblastine in chemotherapy nave pediatric patients with progressive Low Grade Glioma aged 6 months to less than18 years of age at the time of initiation of therapy. Participants will be randomized to Arm …

auditory test
neutrophil count
BRAF
glomerular filtration rate
platelet count
Children's National Medical Center
 (5.4 away) Contact site
  • 0 views
  • 16 Mar, 2020
  • +22 other locations
Safety Tolerability and Efficacy of the Human Cytomegalovirus Vaccine (V160) in Healthy Women 16 to 35 Years of Age (V160-002)

This study will evaluate the safety, tolerability, and efficacy of Human Cytomegalovirus (CMV) vaccine V160 administered in a 2-dose or 3-dose regimen in healthy seronegative women 16 to 35 years of age. Participants will receive blinded V160 on Day 1, Month 2, and Month 6 (3-dose regimen), V160 on Day …

Emerson Clinical Research Institute ( Site 0297)
 (4.6 away) Contact site
  • 6476 views
  • 12 Aug, 2019
  • +95 other locations
Clinical Study of Oral cMET Inhibitor INC280 in Adult Patients With EGFR Wild-type Advanced Non-small Cell Lung Cancer (Geometry Mono-1)

A phase II study to evaluate antitumor activity of oral cMET inhibitor INC280 in adult patients with EGFR wild-type, advanced non-small cell lung cancer (NSCLC) as measured by overall response rate (ORR). The study will also evaluate safety and pharmacokinetics of INC280.

alopecia
EGFR
metastasis
measurable disease
Georgetown University Lombardi Cancer Center
 (7.8 away) Contact site
  • 186 views
  • 26 Oct, 2020
  • +162 other locations
Study Assessing the Efficacy and Safety of Alpelisib Plus Fulvestrant or Letrozole Based on Prior Endocrine Therapy in Patients With PIK3CA Mutation With Advanced Breast Cancer Who Have Progressed on or After Prior Treatments

Study assessing the efficacy and safety of alpelisib plus fulvestrant or letrozole, based on prior endocrine therapy, in patients with PIK3CA mutation with advanced breast cancer who have progressed on or after prior treatments

advanced breast cancer
gonadotropin releasing hormone
fulvestrant
PIK3CA
letrozole
Holy Cross Hospital Pharmacy
 (6.2 away) Contact site
  • 506 views
  • 19 Aug, 2020
  • +118 other locations
Treatment of Hemochromatosis

This study will evaluate the effectiveness of a test called MCV in guiding phlebotomy (blood drawing) therapy in patients with hemochromatosis an inherited disorder that causes too much iron to be absorbed by the intestine. The excess damages body tissues, most severely in the liver, heart, pancreas and joints. Because …

National Institutes of Health Clinical Center, 9000 Rockville Pike
 (9.7 away) Contact site
  • 4 views
  • 05 Nov, 2020
  • 1 location
Phase 2 Study of Poziotinib in Patients With NSCLC Having EGFR or HER2 Exon 20 Insertion Mutation

This is a Phase 2, open-label, multi-center study to evaluate the efficacy and the safety/tolerability of poziotinib in seven patient cohorts for up to 603 previously treated and treatment-nave NSCLC patients. Cohorts 3 and 4 were added with Amendment 1 and three additional cohorts were added with Amendment 2 (Cohorts …

EGFR
osimertinib
stage iv non-small cell lung cancer
HER2
Georgetown University Medical Center
 (7.9 away) Contact site
  • 320 views
  • 20 Sep, 2020
  • +67 other locations
An Efficacy and Safety Study of Erdafitinib (JNJ-42756493) in Participants With Urothelial Cancer

The purpose of this study is to evaluate the objective response rate (complete response [CR]+ partial response [PR]) of the selected dose regimen in participants with metastatic or surgically unresectable urothelial cancers that harbor specific FGFR genomic alterations.

renal function
erdafitinib
measurable disease
adjuvant chemotherapy
dose regimen
Georgetown Univ. Medical Center - Lombardi Cancer Center
 (7.9 away) Contact site
  • 40 views
  • 15 Oct, 2020
  • +140 other locations
Safety and Efficacy Study of Zilucoplan in Subjects With Immune-Mediated Necrotizing Myopathy

The purpose of the study is to evaluate the safety and efficacy of zilucoplan in patients with Immune-Mediated Necrotizing Myopathy (IMNM). Subjects will be randomized in a 1:1 ratio to receive daily SC doses of 0.3 mg/kg zilucoplan or matching placebo for 8 weeks.

National Institute of Health
 (9.7 away) Contact site
  • 9 views
  • 21 Sep, 2020
  • +18 other locations