Hyattsville, Maryland Clinical Trials

A listing of Hyattsville, Maryland clinical trials actively recruiting patient volunteers.

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Found 314 clinical trials
Study of Front Line Therapy With Nivolumab and Salvage Nivolumab + Ipilimumab in Patients With Advanced Renal Cell Carcinoma

Phase II trial of nivolumab in 120 treatment nave patients with ccRCC.

Georgetown University
 (5.8 away) Contact site
  • 82 views
  • 12 Aug, 2020
  • +10 other locations
GE-148-002: A Phase 2 Open-label Single-Center Study to Assess GE-148 (18F) Injection PET Imaging to Detect Localized Prostate Cancer

Background: - GE-148 (18F) is a new drug that is designed to attach to prostate cancer cells. Researchers are interested in combining the drug with a small amount of radioactive material to allow prostate cancer lesions to appear more clearly on imaging scans. Researchers are also interested in determining whether …

National Institutes of Health Clinical Center, 9000 Rockville Pike
 (9.7 away) Contact site
  • 36 views
  • 08 Nov, 2020
  • 1 location
Palbociclib With Fulvestrant for Metastatic Breast Cancer After Treatment With Palbociclib and an Aromatase Inhibitor

This study is being done to look at the role of continuing palbociclib treatment in combination with another type of hormonal therapy (fulvestrant) after disease progression of palbociclib in combination with an aromatase inhibitor.

breast cancer
kidney function tests
metastasis
locally advanced breast cancer
hormone therapy
Kimmel Cancer Center at Johns Hopkins at Sibley Memorial Hospital
 (8.2 away) Contact site
  • 0 views
  • 16 Feb, 2020
  • +4 other locations
Cladribine With Simultaneous or Delayed Rituximab to Treat Hairy Cell Leukemia

Background Hairy cell leukemia (HCL) is highly responsive to but not curable by cladribine (CdA). HCL responds to rituximab, which is not yet standard therapy for HCL. Patients with the CD25-negative variant (HCLv) respond poorly to initial cladribine but do respond to rituximab in anecdotal reports. Deoxycytidine kinase phosphorylates cladribine …

National Institutes of Health Clinical Center, 9000 Rockville Pike
 (9.7 away) Contact site
  • 38 views
  • 12 Nov, 2020
  • 1 location
Feasibility Study of CDDP + CPT-11 + PSK for Extensive-Stage Disease (ED) Small Cell Lung Cancer

The purpose of this study is to examine whether setting test groups of cisplatin + irinotecan + Krestin therapy as first-line treatment and chemotherapy (radiotherapy or radiotherapy + chemotherapy also allowed) combined with Krestin as second-line treatment after exacerbation and comparing with historical control or community control is appropriate as …

neutrophil count
metastasis
irinotecan
platelet count
Toho University Sakura Medical Center
 (5.3 away) Contact site
  • 22 views
  • 07 Nov, 2020
  • +13 other locations
HKI-272 for HER2-Positive Breast Cancer and Brain Metastases

The purpose of this research study is to determine how well neratinib works in treating breast cancer that has spread to the brain. Neratinib is a recently discovered oral drug that may stop breast cancer cells from growing abnormally by inhibiting (or blocking) members of a family of proteins that …

hormone therapy
invasive breast cancer
HER2
endocrine therapy
erbb2
MedStar Georgetown Univeristy Hospital
 (7.9 away) Contact site
  • 47 views
  • 11 Nov, 2020
  • +9 other locations
Safety and Efficacy of Subcutaneous Sarilumab in Improving the Quality of Life in People With Indolent Systemic Mastocytosis

Background Mast cells help the body fight disease and heal wounds. People with indolent systemic mastocytosis (ISM) make too many mast cells. This causes pain, tiredness, digestive problems, and other symptoms. Researchers think the drug sarilumab could help. Objective To see if sarilumab is a safe and effective treatment for …

National Institutes of Health Clinical Center
 (9.7 away) Contact site
  • 8 views
  • 14 Oct, 2020
  • 1 location
Cockroach Immunotherapy in Children and Adolescents

Scientific evidence has shown that, over the past two decades, the combination of cockroach allergy and cockroach exposure is one of the most important factors contributing to the dramatic increase in asthma morbidity seen in inner city children with asthma. Therefore, a major goal of the Inner City Asthma Consortium …

Children's National Medical Center - IMPACT DC
 (5.4 away) Contact site
  • 53 views
  • 19 Jan, 2020
  • +8 other locations
The AVIATOR Study: Trastuzumab and Vinorelbine With Avelumab OR Avelumab & Utomilumab in Advanced HER2+ Breast Cancer

This research study is studying a combination of drugs as a possible treatment for breast cancer. The drugs involved in this study are: Group A: Trastuzumab (Herceptin) + Vinorelbine (Navelbine) Group B: Trastuzumab + Vinorelbine + Avelumab Group C: Trastuzumab + Vinorelbine + Avelumab + Utomilumab (PF-05082566)

trastuzumab
metastasis
HER2
erbb2
herceptin
Georgetown University Medical Center
 (7.9 away) Contact site
  • 16 views
  • 26 Jan, 2020
  • +14 other locations
Dysport in Vulvodynia Phase II Study

This study is designed to define optimal doses of Dysport and evaluate its efficacy and safety compared with placebo for the treatment of vulvodynia. The study will consist of a dose escalation stage (Stage 1) and a dose expansion stage (Stage 2). Both Stage 1 and Stage 2 will consist …

botulinum toxin type a
dysport
James A. Simon, MD, PC
 (6.4 away) Contact site
  • 396 views
  • 02 Nov, 2020
  • +23 other locations