Hyattsville, Maryland Clinical Trials

A listing of Hyattsville, Maryland clinical trials actively recruiting patient volunteers.

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Found 142 clinical trials
Microbial Immune and Metabolic Perturbations by Antibiotics (MIME Study)

More than 250 million courses of antibiotics are prescribed annually in the ambulatory care setting in the United States alone, including more than 40 million in children under 18 years of age. The perception that antibiotic use has minimal attendant adverse side effects contributes to the over-utilization of antibiotics in …

National Institutes of Health Clinical Center, 9000 Rockville Pike
 (9.7 away) Contact site
  • 0 views
  • 18 Jan, 2021
  • 1 location
Phase 1 Study of Ibrutinib and Immuno-Chemotherapy Using Temozolomide Etoposide Doxil Dexamethasone Ibrutinib Rituximab (TEDDI-R) in Primary CNS Lymphoma

BACKGROUND Primary CNS lymphoma (PCNSL) is a rare subtype of diffuse large B-cell lymphoma. The outcome for patients with this diagnosis is significantly worse than for that of systemic DLBCL. Most treatment approaches in the past have included high dose methotrexate and radiation treatment. Most PCNSLs appear to be of …

etoposide
oophorectomy
platelet count
methotrexate
dexamethasone
National Institutes of Health Clinical Center, 9000 Rockville Pike
 (9.7 away) Contact site
  • 1 views
  • 18 Jan, 2021
  • 1 location
MR-guided High Intensity Focused Ultrasound (HIFU) on Pediatric Solid Tumors

The purpose of this study is to determine if Magnetic Resonance guided High Intensity Focused Ultrasound ablative therapy is safe and feasible for children, adolescents, and young adults with refractory or relapsed solid tumors.

biological products
filgrastim
hepatoma
stem cell transplantation
biologic agent
Children's National Medical Center
 (5.4 away) Contact site
  • 274 views
  • 01 Oct, 2020
  • +1 other locations
Administration of Anti-CD19-chimeric-antigen-receptor-transduced T Cells From the Original Transplant Donor to Patients With Recurrent or Persistent B-cell Malignancies After Allogeneic Stem Cell Transplantation

Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is a procedure that transplants bone marrow cells (stem cells) from a matching donor into a recipient in order to allow the donor stem cells to produce cells that will attack the recipient s cancer cells. AlloHSCT is performed when chemotherapy, immunotherapy, or …

high grade lymphoma
chemotherapy regimen
flow cytometry
monoclonal antibodies
chronic lymphocytic leukemia
National Institutes of Health Clinical Center, 9000 Rockville Pike
 (9.7 away) Contact site
  • 9 views
  • 18 Jan, 2021
  • +2 other locations
Impact of Once-Weekly Rifapentine and Isoniazid on the Steady State Pharmacokinetics of Dolutegravir and Darunavir Boosted With Cobicistat in Healthy Volunteers

People with human immunodeficiency virus (HIV) often take several medicines to control HIV. Dolutegravir and darunavir boosted with cobicistat are HIV medicines that people may take. They may also need to take medicines for an infection called latent tuberculosis (TB). Researchers think a once-weekly treatment for latent TB would be …

National Institutes of Health Clinical Center
 (9.7 away) Contact site
  • 41 views
  • 17 Jan, 2021
  • 1 location
Niraparib Plus Carboplatin in Patients With Homologous Recombination Deficient Advanced Solid Tumor Malignancies

This is a multi-institutional Phase I dose-escalation and dose-expansion trial for patients with advanced, solid tumor malignancies who have pre-identified deleterious germline or somatic mutations in the homologous recombination deoxyribonucleic acid (DNA) repair pathway (HR deficient). The trial is designed to assess the efficacy and safety of niraparib plus carboplatin …

renal function
serum pregnancy test
cancer
solid tumor
advanced solid tumor
Lombardi Comprehensive Cancer Center
 (5.8 away) Contact site
  • 7 views
  • 23 Jan, 2021
  • +1 other locations
Title: Therapeutic Targets in African-American Youth With Type 2 Diabetes

Background The pill metformin treats diabetes. But it does not work for all youth, especially African-Americans. The injectable Liraglutide treats type 2 diabetes in adults. Researchers want to understand how these drugs work and if they decrease excess sugar made by the liver in youth with type 2 diabetes. Objective …

sugars
liraglutide
hypoglycemic agents
metformin
continuous glucose monitoring
National Institutes of Health Clinical Center
 (9.7 away) Contact site
  • 9 views
  • 30 Aug, 2020
  • 1 location
Combination Therapy With 3BNC117 and 10-1074 in HIV-Infected Individuals

Background Human immunodeficiency virus (HIV) affects the immune system. The main function of the immune system is protect you from infections and other diseases such as cancer. HIV attacks and cripples the immune system making people more susceptible to a variety of infections and cancers. Currently, the standard treatment for …

antibody test
hiv-1 rna measurement
hiv antibody
HIV Vaccine
cancer
National Institutes of Health Clinical Center
 (9.7 away) Contact site
  • 32 views
  • 17 Jan, 2021
  • 1 location
Trial of Panobinostat in Children With Diffuse Intrinsic Pontine Glioma

This phase I trial studies the side effects and best dose of panobinostat in treating younger patients with diffuse intrinsic pontine glioma (DIPG). Panobinostat may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Stratum 1 treats patients with DIPG that has returned …

panobinostat
dipg
malignant glioma
monoclonal antibodies
corticosteroids
Children's National Medical Center
 (5.4 away) Contact site
  • 27 views
  • 23 Jan, 2021
  • +9 other locations
Physiological Responses and Adaptation of Brown Adipose Tissue to Chronic Treatment With Beta 3-Adrenergic Receptor Agonists

Background Brown adipose tissue (BAT) is a type of fat in the body. It may prevent weight gain, improve insulin sensitivity, and reduce fatty liver. Researchers want to see if BAT helps the body burn energy. Objective To learn more about how BAT works to burn energy. Eligibility Healthy people …

hysterectomy
body mass index
vitamins
insulin resistance
insulin sensitivity
National Institutes of Health Clinical Center
 (9.7 away) Contact site
  • 257 views
  • 01 Jan, 2021
  • 1 location