Hyattsville, Maryland Clinical Trials

A listing of Hyattsville, Maryland clinical trials actively recruiting patient volunteers.

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Found 1700 clinical trials
A Phase 3 Study to Evaluate the Efficacy and Safety of Benralizumab in Patients With Hypereosinophilic Syndrome (HES)

This is a multicentre, randomised, double-blind (DB), parallel-group, placebo-controlled, 24-week Phase 3 study to compare the efficacy and safety of benralizumab versus placebo administered by SC injection Q4W in patients with hypereosinophilic syndrome (HES). This study comprises 2 distinct periods (together defined as the 'main study'): A 24-week, DB treatment …

Research Site
 (9.4 away) Contact site
  • 0 views
  • 04 Nov, 2020
  • +37 other locations
Traditional Versus Early Aggressive Therapy for Multiple Sclerosis Trial

FDA-approved multiple sclerosis (MS) disease-modifying therapies (DMTs) target the relapsing phase of MS but have minimal impact once the progressive phase has begun. It is unclear if, in the relapsing phase, there is an advantage of early aggressive therapy with respect to preventing long-term disability. The infectious risks and other …

Georgetown University
 (7.9 away) Contact site
  • 219 views
  • 29 Nov, 2020
  • +47 other locations
Dose Escalation and Expansion Study of FLX475 Monotherapy and in Combination With Pembrolizumab

This clinical trial is a Phase 1/2, open-label, sequential-group, dose-escalation and cohort expansion study to determine the safety and preliminary anti-tumor activity of FLX475 as monotherapy and in combination with pembrolizumab. The study will be conducted in 2 parts, a dose-escalation phase (Part 1) and a cohort expansion phase (Part …

lung cancer
lymphoma
squamous cell carcinoma
breast cancer
carcinoma
Georgetown - Lombardi Comprehensive Cancer Center
 (7.9 away) Contact site
  • 50 views
  • 29 Nov, 2020
  • +30 other locations
A Study to Confirm Safety and Efficacy of Lecanemab in Participants With Early Alzheimer's Disease

This study will be conducted to evaluate the efficacy of lecanemab in participants with early Alzheimer's disease (EAD) by determining the superiority of lecanemab compared with placebo on the change from baseline in the Clinical Dementia Rating-Sum of Boxes (CDR-SB) at 18 months of treatment in the Core Study. This …

Georgetown University Hospital
 (5.8 away) Contact site
  • 242 views
  • 29 Nov, 2020
  • +266 other locations
A Study to Investigate the Efficacy and Safety of ZX008 (Fenfluramine Hydrochloride) as an Adjunctive Therapy in Children and Adults With Lennox-Gastaut Syndrome

This is a two-part, multicenter, double-blind, parallel-group, placebo controlled study to evaluate the effect of ZX008 when used as adjunctive therapy for the treatment of uncontrolled seizures in children and adults with Lennox-Gastaut syndrome (LGS).

Childrens National Medical Center
 (5.4 away) Contact site
  • 112 views
  • 24 Sep, 2020
  • +98 other locations
Phase 2 Study of Poziotinib in Patients With NSCLC Having EGFR or HER2 Exon 20 Insertion Mutation

This is a Phase 2, open-label, multi-center study to evaluate the efficacy and the safety/tolerability of poziotinib in seven patient cohorts for up to 603 previously treated and treatment-nave NSCLC patients. Cohorts 3 and 4 were added with Amendment 1 and three additional cohorts were added with Amendment 2 (Cohorts …

osimertinib
EGFR
HER2
stage iv non-small cell lung cancer
Georgetown University Medical Center
 (7.9 away) Contact site
  • 320 views
  • 20 Sep, 2020
  • +67 other locations
Understanding and Predicting Breast Cancer Events After Treatment

This study is being done to see if patients receiving chemotherapy for breast cancer affects the heart, the ability to exercise and fatigue when compared to patients who do not have cancer.

stage iv breast cancer
female breast cancer
MedStar Washington Hospital Center
 (5.3 away) Contact site
  • 280 views
  • 18 Oct, 2020
  • +64 other locations
Safety and Efficacy Study of Viaskin Peanut in Peanut-allergic Young Children 1-3 Years of Age

The study aims to assess the safety and efficacy of Viaskin Peanut to induce desensitization to peanut in peanut-allergic children 1 to 3 years of age after a 12-month treatment by EPicutaneous ImmunoTherapy (EPIT).

a 12
Children's national Health System
 (5.4 away) Contact site
  • 246 views
  • 01 Nov, 2020
  • +50 other locations
A Trial of Lopinavir/Ritonavir Dosed According to the Who Pediatric Weight Band Dosing Guidelines

The main purpose of this study is to measure the amount of lopinavir/ritonavir (two anti-HIV medications) in the blood. Results from this study will be compared to the levels of the drugs that have been found in other studies that showed that these medications were safe and effective.

HIV Vaccine
lopinavir
ritonavir
kaletra
lopinavir/ritonavir
Howard University Washington, DC NICHD CRS (5044)
 (5.1 away) Contact site
  • 340 views
  • 08 Nov, 2020
  • +55 other locations
The iCat2 GAIN (Genomic Assessment Informs Novel Therapy) Consortium Study

This research study is evaluating the use of specialized testing of solid tumors including sequencing. The process of performing these specialized tests is called tumor profiling. The tumor profiling may result in identifying changes in genes of the tumor that indicate that a particular therapy may have activity. This is …

Children's National Medical Center
 (5.4 away) Contact site
  • 16 views
  • 23 Dec, 2019
  • +8 other locations