Hyattsville, Maryland Clinical Trials

A listing of Hyattsville, Maryland clinical trials actively recruiting patient volunteers.

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Found 6 clinical trials
A Study of Androgen Annihilation in High-Risk Biochemically Relapsed Prostate Cancer

This is a randomized, open-label, three-arm, phase 3 study in men with biochemically recurrent prostate cancer and PSA doubling time 9 months at the time of study entry.

serum testosterone
apalutamide
abiraterone
gonadorelin
immunological adjuvant
Georgetown University Medical Center
 (7.8 away) Contact site
  • 496 views
  • 03 Jun, 2019
  • +67 other locations
Efficacy and Safety of Pembrolizumab (MK-3475) Plus Enzalutamide Plus Androgen Deprivation Therapy (ADT) Versus Placebo Plus Enzalutamide Plus ADT in Participants With Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) (MK-3475-991/KEYNOTE-991)

This study will assess the efficacy and safety of pembrolizumab plus enzalutamide plus ADT versus placebo plus enzalutamide plus ADT in participants with mHSPC. The primary hypothesis is that in participants with mHSPC, the combination of pembrolizumab plus enzalutamide plus ADT is superior to placebo plus enzalutamide plus ADT with …

Sibley Memorial Hospital ( Site 0275)
 (8.1 away) Contact site
  • 272 views
  • 05 Dec, 2020
  • +184 other locations
Muscadine Plus (MPX) In Men With Prostate Cancer

This research is being done to determine if men with rising PSA after initial therapy for localized prostate cancer who display the Alanine/Alanine SOD2 genotype of MnSOD and supplement their diet with MPX have greater decrease in PSA slope following treatment compared to men that do not supplement with MPX.

definitive treatment
cancer
prostate tumor
brachytherapy
testosterone level
Sibley Memorial Hospital
 (8.2 away) Contact site
  • 22 views
  • 20 Jul, 2020
  • +13 other locations
Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

This phase III trial studies how well standard systemic therapy with or without definitive treatment (prostate removal surgery or radiation therapy) works in treating participants with prostate cancer that has spread to other places in the body. Addition of prostate removal surgery or radiation therapy to standard systemic therapy for …

MedStar Washington Hospital Center
 (5.4 away) Contact site
  • 247 views
  • 28 Nov, 2020
  • +270 other locations
Study of Pembrolizumab (MK-3475) Plus Olaparib Versus Abiraterone Acetate or Enzalutamide in Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-7339-010/KEYLYNK-010)

The purpose of this study is to assess the efficacy and safety of the combination of the polyadenosine 5'-diphosphoribose poly(ADP-ribose) polymerase (PARP) inhibitor olaparib and pembrolizumab in the treatment of participants with mCRPC who have failed to respond to either abiraterone acetate or enzalutamide (but not both) and to chemotherapy. …

antiandrogen therapy
serum testosterone
diphosphonates
ct scan
bisphosphonate
Sibley Memorial Hospital ( Site 0096)
 (8.1 away) Contact site
  • 394 views
  • 04 Dec, 2020
  • +202 other locations
Phase 3 Study of ProstAtak Immunotherapy With Standard Radiation Therapy for Localized Prostate Cancer

The purpose of this study is to evaluate the effectiveness of ProstAtak immunotherapy in combination with radiation therapy for patients with intermediate-high risk localized prostate cancer. ProstAtak kills tumor cells and stimulates a cancer vaccine effect. Killing tumor cells in an immune stimulatory environment induces the body's immune system to …

antiandrogen therapy
androgen suppression
external beam radiation therapy
cancer vaccine
androgens
Sibley Memorial Hospital
 (8.2 away) Contact site
  • 1420 views
  • 05 Dec, 2020
  • +76 other locations