Hyattsville, Maryland Clinical Trials

A listing of Hyattsville, Maryland clinical trials actively recruiting patient volunteers.

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Found 19 clinical trials
Neoadjuvant Androgen Deprivation Therapy Combined With Enzalutamide and Abiraterone Using Multiparametric MRI and 18FDCFPyL PET/CT in Newly Diagnosed Prostate Cancer

Background Prostate cancer is a common cancer among men. There are several ways to treat it, including hormone blocking drugs, radiation therapy, and surgery. Researchers want to combine abiraterone and enzalutamide to see if there is a better way to treat prostate cancer. They also want to study a new …

National Institutes of Health Clinical Center
 (9.7 away) Contact site
  • 16 views
  • 20 Aug, 2020
  • 1 location
GE-148-002: A Phase 2 Open-label Single-Center Study to Assess GE-148 (18F) Injection PET Imaging to Detect Localized Prostate Cancer

Background: - GE-148 (18F) is a new drug that is designed to attach to prostate cancer cells. Researchers are interested in combining the drug with a small amount of radioactive material to allow prostate cancer lesions to appear more clearly on imaging scans. Researchers are also interested in determining whether …

National Institutes of Health Clinical Center, 9000 Rockville Pike
 (9.7 away) Contact site
  • 36 views
  • 08 Nov, 2020
  • 1 location
A Study to Evaluate the Safety and Efficacy of Crizanlizumab in Sickle Cell Disease Related Priapism

The goal of the study is to evaluate the efficacy and safety of crizanlizumab in SCD patients with priapism.

Children s National Hospital SC
 (5.3 away) Contact site
  • 23 views
  • 28 Oct, 2020
  • +16 other locations
Radium-223 in Biochemically Recurrent Prostate Cancer

Background Some men who have been treated for localized prostate cancer with surgery or radiation still show signs of the disease in their blood. This is called biochemically recurrent prostate cancer. Radium-223 is a small molecule. It uses radiation to kill cancer cells and improves survival in advanced prostate cancer. …

National Institutes of Health Clinical Center
 (9.4 away) Contact site
  • 0 views
  • 02 Dec, 2020
  • 1 location
A Study for Subjects With Prostate Cancer Who Previously Participated in an Enzalutamide Clinical Study

The purpose of this study is to collect long term safety data in subjects who are continuing to derive clinical benefit from treatment with Enzalutamide from the subjects participation in an enzalutamide clinical study sponsored by Astellas or Medivation (i.e., parent study) which has completed, at a minimum, the primary …

androgen suppression
androgens
prednisone
antiandrogen therapy
abiraterone
Site US10050
 (7.0 away) Contact site
  • 1404 views
  • 05 Dec, 2020
  • +130 other locations
Combining CRLX101 a Nanoparticle Camptothecin With Enzalutamide in People With Progressive Metastatic Castration Resistant Prostate Cancer Following Prior Enzalutamide Treatment

Background Some prostate cancer keeps growing even when testosterone in the body drops to very low levels. This is called castrate-resistant prostate cancer. One treatment is enzalutamide. This is a modern hormonal therapy. But it only works for a certain amount of time and then the cancer becomes resistant to …

5-alpha reductase inhibitors
androgens
cancer
enzalutamide
bone scan
National Institutes of Health Clinical Center
 (9.7 away) Contact site
  • 14 views
  • 31 Aug, 2020
  • 1 location
Study of I-131-1095 Radiotherapy in Combination With Enzalutamide in Patients With Metastatic Castration-resistant Prostate Cancer Who Are Chemotherapy Naive and Have Progressed on Abiraterone

This is a multicenter, randomized, controlled, phase 2 clinical trial designed to evaluate the safety and efficacy of I-131-1095 radiotherapy in combination with enzalutamide compared to enzalutamide alone in patients with prostate-specific membrane antigen (PSMA)-avid metastatic castration resistant prostate cancer (mCRPC) who have progressed on abiraterone. Patients must be chemotherapy-naive …

adenocarcinoma
soft tissue disease
abiraterone
cancer
pet/ct scan
Medstar Georgetown University Hospital
 (7.9 away) Contact site
  • 23 views
  • 20 Nov, 2020
  • +23 other locations
Multi-Epitope TARP Peptide Autologous Dendritic Cell Vaccination in Men With Stage D0 Prostate Cancer

Background Men who continue to have an elevated or rising prostate specific antigen (PSA) level after their primary prostate cancer treatment are at increased risk for their cancer to progress. The time it takes to progress is highly variable. One way to predict this progression is based on the change …

5-alpha reductase inhibitors
brachytherapy
cancer
definitive treatment
cancer vaccine
National Institutes of Health Clinical Center, 9000 Rockville Pike
 (9.7 away) Contact site
  • 6 views
  • 30 Sep, 2020
  • 1 location
Docetaxel With or Without Ascorbic Acid in Treating Patients With Metastatic Prostate Cancer

This randomized phase II trial studies how well docetaxel works when given with or without ascorbic acid in treating patients with prostate cancer that has spread to other places in the body. Drugs used in chemotherapy, such as docetaxel, work in different ways to stop the growth of tumor cells, …

metastatic prostate cancer
docetaxel
carcinoma
cancer
tumor cells
Sibley Memorial Hospital
 (8.2 away) Contact site
  • 25 views
  • 26 Jul, 2020
  • +5 other locations
Study of TGF- Receptor Inhibitor Galunisertib (LY2157299) and Enzalutamide in Metastatic Castration-resistant Prostate Cancer

The primary objective of this study is to compare the progression free survival (PFS) of patients with metastatic castration-resistant prostate cancer treated with enzalutamide in combination with LY2157299 (Arm 1) versus enzalutamide alone (Arm 2).

metastatic castration-resistant prostate cancer
abiraterone
castration-resistant prostate cancer
enzalutamide
Sibley Memorial Hospital
 (8.2 away) Contact site
  • 20 views
  • 03 Aug, 2020
  • +3 other locations