Hyattsville, Maryland Clinical Trials

A listing of Hyattsville, Maryland clinical trials actively recruiting patient volunteers.

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Found 50 clinical trials
Proton Therapy vs. IMRT for Low or Intermediate Risk Prostate Cancer

We are studying whether men being treated for prostate cancer have the same amount of side effects from either one of two different external radiation treatments: IMRT or PBT. With IMRT, a number of x-ray beams are used to shape the radiation to the prostate. PBT is another type of …

external beam radiation therapy
adenocarcinoma of prostate
adenocarcinoma
finasteride
digital rectal examination
University of Maryland Medical Center
 (2.8 away) Contact site
  • 173 views
  • 16 Sep, 2020
  • +11 other locations
Study of TGF- Receptor Inhibitor Galunisertib (LY2157299) and Enzalutamide in Metastatic Castration-resistant Prostate Cancer

The primary objective of this study is to compare the progression free survival (PFS) of patients with metastatic castration-resistant prostate cancer treated with enzalutamide in combination with LY2157299 (Arm 1) versus enzalutamide alone (Arm 2).

castration-resistant prostate cancer
abiraterone
metastatic castration-resistant prostate cancer
enzalutamide
Sibley Memorial Hospital
 (8.2 away) Contact site
  • 20 views
  • 03 Aug, 2020
  • +3 other locations
RE-sensitizing With Supraphysiologic Testosterone to Overcome REsistance (The RESTORE Study)

Single-arm, single site, open label study of the effects of parenteral testosterone followed by enzalutamide, abiraterone or castration-only therapy in men with metastatic CRPC who previously progressed on one of these forms of therapy. The study will enroll four cohorts of patients: men with metastatic CRPC who have progressed on …

antiandrogens
adenocarcinoma
neutrophil count
surgical castration
bicalutamide
Sibley Memorial Hospital
 (8.1 away) Contact site
  • 14 views
  • 20 May, 2020
  • +1 other locations
Study of RS1 Ocular Gene Transfer for X-linked Retinoschisis

Background X-linked juvenile retinoschisis (XLRS) is caused by changes in the RS1 gene. These changes cause abnormal function of the eye protein retinoschisin. Without normal retinoschisin, the layers of the retina split and vision is lost. Researchers want to try to introduce a healthy RS1 gene into eye cells, to …

National Institutes of Health Clinical Center, 9000 Rockville Pike
 (9.7 away) Contact site
  • 53 views
  • 03 Aug, 2020
  • 1 location
Study to Compare Capsule and Liquid Formulations of Enzalutamide After Single Dose Administration Under Fasting Conditions in Prostate Cancer

Background Enzalutamide is given to treat metastatic prostate cancer. But it takes 4 pills to deliver the effective dose. This can be difficult for people already taking multiple drugs. And swallowing may be difficult for some people. Researchers want to test out a new way of giving enzalutamide by mouth. …

metastatic prostate cancer
enzalutamide
neutrophil count
prostate cancer metastatic
carcinoma
National Institutes of Health Clinical Center
 (9.7 away) Contact site
  • 31 views
  • 01 Dec, 2020
  • 1 location
PROSTVAC in Combination With Nivolumab in Men With Prostate Cancer

Background The immune system is the cells and organs in the body that recognize and fight infection and cancer. The PROSTVAC vaccine might teach the immune system to find and kill certain prostate cancer cells. Nivolumab is a drug that allows the immune system to fight tumors. Itmight help PROSTVAC …

prostatectomy
progressive disease
bicalutamide
antiandrogen therapy
biopsy of prostate
National Institutes of Health Clinical Center
 (9.7 away) Contact site
  • 38 views
  • 03 Dec, 2020
  • 1 location
Abiraterone Acetate and Antiandrogen Therapy With or Without Cabazitaxel and Prednisone in Treating Patients With Metastatic Castration-Resistant Prostate Cancer Previously Treated With Docetaxel

This randomized phase II trial studies how well abiraterone acetate and antiandrogen therapy, with or without cabazitaxel and prednisone, work in treating patients with castration-resistant prostate cancer previously treated with docetaxel that has spread to other parts of the body. Androgens can cause the growth of prostate cancer cells. Hormone …

antiandrogens
adenocarcinoma
measurable disease
neutrophil count
surgical castration
Sibley Memorial Hospital
 (8.2 away) Contact site
  • 1518 views
  • 27 May, 2020
  • +440 other locations
Combination Immunotherapy in Biochemically Recurrent Prostate Cancer

Background Some people with prostate cancer have a rise in prostate-specific antigen (PSA). This can happen even after treatments like radiation and surgery. Androgen deprivation therapy (ADT) drugs and close monitoring are one standard way to treat this group of people. Another way is to monitor people and their PSA …

bicalutamide
antiandrogen therapy
carcinoma
metastatic prostate cancer
orchiectomy
National Institutes of Health Clinical Center
 (9.7 away) Contact site
  • 56 views
  • 14 Oct, 2020
  • 1 location
Prostate SBRT for Locally Recurrent Prostate Cancer After Prior Radiotherapy

Background Prostate cancer is the second leading cause of cancer death in U.S. men. Radiation is an effective treatment for most patients with localized prostate cancer, but sometimes the tumor returns. Researchers want to see if a highly focused type of radiation can help. It is given in only 5 …

external beam radiation therapy
adenocarcinoma
recurrent prostate cancer
prostate tumor
ct scan
National Institutes of Health Clinical Center
 (9.7 away) Contact site
  • 9 views
  • 26 Oct, 2020
  • 1 location
Study of Human Non-Shivering Thermogenesis and Basal Metabolic Rate

Background Changes in how a person s body burns energy or calories can affect their weight over time. The lowest level of energy the body needs to function is called basal metabolic rate. In the cold, we burn extra energy, even before we start to shiver. This is called non-shivering …

blood test
National Institutes of Health Clinical Center, 9000 Rockville Pike
 (9.7 away) Contact site
  • 321 views
  • 30 Nov, 2020
  • 1 location