Hyattsville, Maryland Clinical Trials

A listing of Hyattsville, Maryland clinical trials actively recruiting patient volunteers.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 989 clinical trials
Phase 1/2 Dose Finding and Safety Study of Ibrutinib in Pediatric Subjects With Chronic Graft Versus Host Disease (cGVHD)

Dose Finding and Safety Study of Ibrutinib in Pediatric Subjects with Chronic Graft Versus Host Disease (cGVHD)

cell transplantation
ibrutinib
immunosuppression
Children's National Medical Center
 (5.4 away) Contact site
  • 47 views
  • 27 May, 2020
  • +49 other locations
A Study of Erdafitinib Compared With Vinflunine or Docetaxel or Pembrolizumab in Participants With Advanced Urothelial Cancer and Selected Fibroblast Growth Factor Receptor (FGFR) Gene Aberrations

The purpose of this study is to evaluate efficacy of erdafitinib versus chemotherapy or pembrolizumab in participants with advanced urothelial cancer harboring selected fibroblast growth factor receptor (FGFR) aberrations who have progressed after 1 or 2 prior treatments, at least 1 of which includes an anti-PD-(L) 1 agent (cohort 1) …

docetaxel
growth factor
pembrolizumab
erdafitinib
carcinoma
Maryland Oncology Hematology, PA
 (4.1 away) Contact site
  • 271 views
  • 12 Oct, 2020
  • +522 other locations
Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction

Heart failure with preserved ejection fraction (HFPEF) is common and deadly but without therapy. Inconclusive studies such as TOPCAT (Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist) suggest spironolactone may be effective in HFPEF, but it is generic and will not be studied by industry. SPIRRIT is …

spironolactone
natriuretic peptide
b-type natriuretic peptide
n-terminal pro-bnp
aldosterone
Howard University Hospital
 (5.1 away) Contact site
  • 46 views
  • 06 Jan, 2020
  • +118 other locations
Study of the Efficacy and Safety of Lonafarnib / Ritonavir With and Without Pegylated Interferon -Alfa-2a

Two LNF-containing regimens will be evaluated in the D-LIVR Phase 3 study: (1) LNF/RTV/PEG IFN-alfa-2a and (2) LNF/RTV. Each of these arms will have efficacy endpoints that measure clinical benefit with regard to viral suppression and alanine aminotransferase (ALT) normalization. For each LNF-containing regimen, a composite endpoint of EOT (48 …

National Institutes of Health
 (9.6 away) Contact site
  • 236 views
  • 04 Dec, 2020
  • +170 other locations
Safety Tolerability and Efficacy of Cilofexor in Non-Cirrhotic Adults With Primary Sclerosing Cholangitis

The primary objective of this study is to evaluate whether cilofexor reduces the risk of fibrosis progression among non-cirrhotic adults with primary sclerosing cholangitis (PSC).

fibrosis
cilofexor
platelet count
MedStar Georgetown University Hospital
 (7.9 away) Contact site
  • 83 views
  • 29 Nov, 2020
  • +217 other locations
A Study of DCC-2618 vs Sunitinib in Advanced GIST Patients After Treatment With Imatinib

This is a 2-arm, randomized, open-label, international, multicenter study comparing the efficacy of DCC-2618 to sunitinib in GIST patients who progressed on or were intolerant to first-line anticancer treatment with imatinib. Approximately 426 patients will be randomized in a 1:1 ratio to DCC-2618 150 mg once daily (QD) (continuous dosing …

measurable disease
amylase
lipase
dcc-2618
sunitinib
Washington Cancer Institute at MedStar Washington Hospital Center
 (5.3 away) Contact site
  • 43 views
  • 28 Oct, 2020
  • +128 other locations
Study of IMMU-132 in HR+/HER2- MBC (TROPICS-02)

This is an open-label, randomized, multicenter Phase 3 study to compare the efficacy and safety of Sacituzumab Govitecan versus TPC in subjects with metastatic or locally recurrent inoperable HR+/HER2- MBC, after failure of at least 2, and no more than 4, prior chemotherapy regimens for metastatic disease.

kidney function tests
capecitabine
eribulin
metastasis
cancer chemotherapy
Georgetown University Medical Center
 (7.9 away) Contact site
  • 66 views
  • 05 Oct, 2020
  • +104 other locations
Efficacy Safety and Tolerability of Atogepant for the Prevention of Chronic Migraine

This study will evaluate the efficacy, safety and tolerability of atogepant in participants with chronic migraine. This study includes a 12-week treatment period.

headache
migraine
GW Medical Faculty Associates
 (7.1 away) Contact site
  • 576 views
  • 01 Nov, 2020
  • +146 other locations
A Phase 3 Multi-Center Randomized Double-Blind Placebo-Controlled Study of Fostamatinib Disodium in the Treatment of wAIHA

The primary objective of this study is to assess the efficacy of fostamatinib in subjects with warm antibody autoimmune hemolytic anemia (wAIHA).

Georgetown University
 (7.8 away) Contact site
  • 113 views
  • 26 Oct, 2020
  • +105 other locations
Evaluation of Long Term Safety and Efficacy of Glepaglutide in Treatment of SBS

The primary objective of the trial is to evaluate the long-term safety of glepaglutide treatment in patients with short bowel syndrome (SBS). Glepaglutide is the International Nonproprietary Name and USAN for ZP1848.

Georgetown University Medical Center
 (7.9 away) Contact site
  • 173 views
  • 28 Nov, 2020
  • +50 other locations