Hyattsville, Maryland Clinical Trials

A listing of Hyattsville, Maryland clinical trials actively recruiting patient volunteers.

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Found 135 clinical trials
A Study of TSR-022 in Participants With Advanced Solid Tumors (AMBER)

This is a multicenter, open-label, first-in-human Phase 1 study evaluating the anti-T cell immunoglobulin and mucin containing protein-3 (TIM-3) antibody TSR-022. The study will be conducted in 2 parts: with Part 1 consisting of dose escalation and Part 2 dose expansion. Part 1 will determine the recommended Phase 2 dose …

pd-l1
carboplatin
docetaxel
metastatic solid tumor
carcinoma
GSK Investigational Site
 (7.8 away) Contact site
  • 0 views
  • 03 Dec, 2020
  • +119 other locations
Vincristine Sulfate Liposome Injection (Marqibo ) in Combination With UK ALL R3 Induction Chemotherapy for Children Adolescents and Young Adults With Relapsed ALL

This is a pilot study utilizing Marqibo (vincristine sulfate liposome injection) combined with dexamethasone, mitoxantrone and asparaginase (UK ALL R3) for relapsed acute lymphoblastic leukemia (ALL).

residual tumor
acute leukemia
left ventricular fractional shortening
hydroxyurea
vincristine
Children's National Medical Center
 (5.4 away) Contact site
  • 0 views
  • 06 May, 2020
  • +32 other locations
Walking Therapy In Hemiparetic Stroke Patients Using Robotic-Assisted Treadmill Training

The overall goal of this study is to determine whether robotic-assisted gait training is better than standard physical therapy treatments for improving walking ability in hemiparetic stroke patients.

other therapy
hemiparesis
gait training
stroke
National Rehabilitation Hospital
 (5.4 away) Contact site
  • 19 views
  • 07 Nov, 2020
  • 1 location
Selinexor (KPT-330) in Combination With Temozolomide and Radiation Therapy in Patients With Newly Diagnosed Glioblastoma

Background Glioblastoma is a type of brain cancer. Treatments include radiation, chemotherapy, and surgery. But survival rates are poor. Researchers think that the drug selinexor, when combined with chemotherapy and radiation, might help. Objective To learn the highest dose of selinexor that people with brain cancer can tolerate when given …

cancer
MRI
glioblastoma multiforme
ct scan
platelet count
National Institutes of Health Clinical Center
 (9.7 away) Contact site
  • 43 views
  • 04 Dec, 2020
  • 1 location
Virtual Reality Mobility Assessment of Functional Vision in Retinal Disease

Background The retina is a thin layer of tissue at the back of the eye. Retinal disease usually reduces a person s mobility because it affects how he or she moves through familiar and unfamiliar environments. Researchers want to see if a virtual reality (VR) tool can provide an easier …

other disease
electroretinogram
eye drops
eye exam
National Institutes of Health Clinical Center
 (9.7 away) Contact site
  • 8 views
  • 27 Dec, 2020
  • +1 other locations
PET Imaging of Cyclooxygenases in Dementia

Background About 5 million adults in the U.S. have Alzheimer s disease or another adult-onset neurodegenerative disorder. Many studies have found that inflammation in the brain contributes to these diseases. Researchers want to find a better way to measure this inflammation. Objective To learn if two new radiolabeled drugs, [11C]PS13 …

alzheimer's disease
cognitive impairment
neurodegenerative disorders
positron emission tomography
neuropsychological test
National Institutes of Health Clinical Center
 (9.4 away) Contact site
  • 0 views
  • 18 Jan, 2021
  • 1 location
Effect of Acute Alcohol Intoxication on Neural Processes During Decisions to Engage in HIV Risk Behaviors

Background People who binge drink are more likely to have risky sexual encounters, and alcohol changes brain activity associated with reward decisions related to those behaviors. Researchers want to better understand how alcohol s effects on risky sexual behavior that might lead people to contract sexually transmitted diseases (STDs) like …

National Institutes of Health Clinical Center
 (9.4 away) Contact site
  • 0 views
  • 17 Jan, 2021
  • 1 location
Safety Tolerability Pharmacokinetics and Pharmacodynamics of Fx-5A in Healthy Volunteers

Background Heart disease is the leading cause of death, disability, and healthcare expense in the United States. Researchers think a new drug called Fx-5A may be useful to treat different cardiovascular diseases and inflammation. Objective To understand the safety, tolerability, and effects of Fx-5A. Eligibility Healthy people ages 18 and …

heart disease
National Institutes of Health Clinical Center
 (9.4 away) Contact site
  • 0 views
  • 17 Jan, 2021
  • 1 location
Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms

The primary objective of this phase 1 trial is to determine the maximum tolerated dose (MTD), food effect, safety and tolerability of oral ONC206 in patients with recurrent, primary CNS neoplasms.

cancer
MRI
astrocytoma
ependymoma
oligodendroglioma
National Institutes of Health
 (9.4 away) Contact site
  • 0 views
  • 04 Nov, 2020
  • 1 location
Evaluating the Safety Tolerability Pharmacokinetics and Antiviral Activity of the Monoclonal Antibody PGT121.414.LS Administered Alone and in Combination With VRC07-523LS Via Intravenous or Subcutaneous Infusions in Healthy HIV-uninfected Adult Participants

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics, and antiviral activity of the monoclonal antibody PGT121.414.LS administered alone and in combination with VRC07-523LS via intravenous or subcutaneous infusions in healthy, HIV-uninfected adult participants.

HIV Vaccine
hiv test
artificial insemination
antiviral drugs
hormonal contraception
George Washington Univ. CRS
 (7.0 away) Contact site
  • 0 views
  • 07 Sep, 2020
  • +4 other locations