Hyattsville, Maryland Clinical Trials

A listing of Hyattsville, Maryland clinical trials actively recruiting patient volunteers.

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Found 135 clinical trials
Research Study Utilizing Expanded Multi-antigen Specific Lymphocytes for the Treatment of Solid Tumors

Patients with high-risk solid tumors, those that are refractory to standard up front therapy or relapse after completion of therapy, have a very poor prognosis despite attempts to induce remission with salvage regimen. Novel therapies are critical for this patient population with high-risk cancer. The ability of tumors to be …

conventional therapy
cancer
lymphoma
sarcoma
Children's National Medical Center
 (5.4 away) Contact site
  • 0 views
  • 23 Jan, 2021
  • 1 location
Dopaminergic Modulation of Brain Activation Using Simultaneous PET/Pharmacological MRI

Background Dopamine (DA) is a chemical signal in the brain linked to learning, memory, and habits. Stimulant drugs like methylphenidate can increase DA in the brain. Researchers want to measure DA with and without this drug. They want to learn how methylphenidate and brain dopamine affect body responses, mood, and …

National Institutes of Health Clinical Center
 (9.7 away) Contact site
  • 0 views
  • 15 Oct, 2020
  • 1 location
Cytokine Microdialysis for Real-Time Immune Monitoring in Glioblastoma Patients Undergoing Checkpoint Blockade

Background Glioblastoma (GBM) brain tumors almost always return after treatment. When that happens the tumor can never completely be removed by surgery, so most people also receive drugs. Researchers want to see if combining the drugs nivolumab and BMS-986016 may help. Objectives To study how nivolumab affects the brain s …

MRI
recurrent glioblastoma
brain tumor
National Institutes of Health Clinical Center
 (9.7 away) Contact site
  • 19 views
  • 18 Oct, 2020
  • 1 location
A Single-blind Study to Evaluate the Safety Tolerability and Immunogenicity of a Hantaan Puumala Virus DNA Vaccine

This is a single-center, randomized, single-blinded study of the Hantaan virus HTNV DNA vaccine alone, Puumala virus PUUV DNA vaccine alone, and mixed Hantaan/Puumala HTNV/PUUV DNA vaccines delivered intramuscularly IM by the needle-free PharmaJet Stratus DSJI device.

WRAIR Clinical Trials Center
 (6.2 away) Contact site
  • 17 views
  • 23 Jan, 2021
  • 1 location
Genomic Responses of Human Immune and Non-Immune Cells to Glucocorticoids

Background The immune system defends the body against bacteria and other harmful invaders. But it can overact and attack healthy cells by mistake. The group of drugs called glucocorticoids (GCs) can calm down an overactive immune system. But they often cause negative side effects. Researchers want to learn how human …

National Institutes of Health Clinical Center
 (9.7 away) Contact site
  • 0 views
  • 25 Oct, 2020
  • 1 location
Allogeneic Virus-specific T Cell Lines (VSTs)

The primary purpose of the study is to evaluate whether most closely HLA-matched multivirus-specific T cell lines obtained from a bank of allogeneic virus-specific T cell lines (VSTs) have antiviral activity against three viruses: EBV, CMV and adenovirus. Reconstitution of anti-viral immunity by donor-derived VSTs has shown promise in preventing …

Childrens National Medical Center
 (5.4 away) Contact site
  • 1 views
  • 23 Jan, 2021
  • 1 location
Title: Moxetumomab Pasudotox-tdfk (Lumoxiti ) and Rituximab (Rituxan ) for Relapsed Hairy Cell Leukemia

Background Hairy cell leukemia (HCL) is a rare, slow-growing blood cancer in which the bone marrow makes too many of certain white blood cells. The antibody Rituximab binds to a protein in cancerous white blood cells and is often used to treat HCL. Researchers want to see if combining it …

National Institutes of Health Clinical Center
 (9.7 away) Contact site
  • 1 views
  • 11 Dec, 2020
  • 1 location
A Study to Evaluate the Safety Tolerability of DN1508052-01 in Advanced Solid Tumors

This is a phase I, open-label, multicenter study in adult patients with advanced solid tumors that have progressed despite standard therapy or for which no standard therapy exists. DN1508052-01 will be administered subcutaneously on Day 1, Day 8 and Day 15 in 28-day cycles. Other dose regimens may be explored …

Washington University School of Medicine - Siteman Cancer Center
 (6.7 away) Contact site
  • 30 views
  • 23 Jan, 2021
  • +2 other locations
Safety of Belimumab in People With Idiopathic CD4 Lymphopenia and Autoantibodies (Phoebe)

Background People with Idiopathic CD4 lymphopenia (ICL) have lower numbers of a type of white blood cell called CD4 cells. White blood cells fight against infections. Low levels of CD4 cells may make a person more likely to get sick. There are no approved treatments for ICL. Researchers think a …

National Institutes of Health Clinical Center
 (9.7 away) Contact site
  • 109 views
  • 13 Dec, 2020
  • 1 location
A Phase 1 Open Label Trial of Intravenous Administration of MVA-BN-Brachyury Vaccine in Patients With Advanced Cancer

A Phase 1 open label trial of intravenous administration of MVA-BN-Brachyury vaccine in patients with advanced cancer. Patients with metastatic or unresectable locally advanced malignant solid tumors will be enrolled and treated according to a 3+3 dose escalation scheme. Up to 3 dose levels will be explored. Patients will receive …

National Cancer Institute
 (9.7 away) Contact site
  • 2 views
  • 23 Jan, 2021
  • 1 location