Hyattsville, Maryland Clinical Trials

A listing of Hyattsville, Maryland clinical trials actively recruiting patient volunteers.

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Found 139 clinical trials
Caregiver-Provided Life Review for Persons with Dementia in Care Facilities

Five percent of community‐dwelling older Americans experience depression. The rate is higher among persons with dementia (PWD)(30%). One in 10 older adults (5.6 million) has Alzheimer’s dementia (2019) and 70% are cared for by their families. This public health issue will worsen as the aging baby boomers grow from 55 …

 (3.6 away) Contact site
  • 21 Oct, 2020
  • +252 other locations
A Study to Evaluate MEDI5752 and Axitinib in Subjects With Advanced Renal Cell Carcinoma

The purpose of this study is to evaluate MEDI5752 in combination with subjects with advanced renal cell carcinoma.

Research Site
 (7.8 away) Contact site
  • 05 Nov, 2020
  • +16 other locations
Technical Development of Cardiovascular Magnetic Resonance Imaging

The goal of this study is to develop advances in cardiovascular diagnostic and treatment methods using magnetic resonance imaging (MRI), a test that uses a strong magnetic field and radio waves to show anatomic detail. For the scan, the patient lies on a table in a cylinder containing a magnetic …

National Institutes of Health Clinical Center, 9000 Rockville Pike
 (9.7 away) Contact site
  • 07 Nov, 2020
  • 1 location
Genomic Responses of Human Immune and Non-Immune Cells to Glucocorticoids

Background The immune system defends the body against bacteria and other harmful invaders. But it can overact and attack healthy cells by mistake. The group of drugs called glucocorticoids (GCs) can calm down an overactive immune system. But they often cause negative side effects. Researchers want to learn how human …

National Institutes of Health Clinical Center
 (9.7 away) Contact site
  • 25 Oct, 2020
  • 1 location
A Single-blind Study to Evaluate the Safety Tolerability and Immunogenicity of a Hantaan Puumala Virus DNA Vaccine

This is a single-center, randomized, single-blinded study of the Hantaan virus HTNV DNA vaccine alone, Puumala virus PUUV DNA vaccine alone, and mixed Hantaan/Puumala HTNV/PUUV DNA vaccines delivered intramuscularly IM by the needle-free PharmaJet Stratus DSJI device.

WRAIR Clinical Trials Center
 (6.2 away) Contact site
  • 02 Mar, 2020
  • 1 location
ESP1/SARC025 Global Collaboration: A Phase I Study of a Combination of the PARP Inhibitor Niraparib and Temozolomide and/or Irinotecan Patients With Previously Treated Incurable Ewing Sarcoma

The purpose of this study is to define the dose-limiting toxicities and maximum tolerated dose of the poly ADP-ribose polymerase inhibitor niraparib and escalating doses of temozolomide and/or irinotecan in patients with pre-treated incurable Ewing sarcoma.

cell transplantation
measurable disease
cancer chemotherapy
National Cancer Institute
 (9.7 away) Contact site
  • 18 Nov, 2020
  • +4 other locations
Experimental Infection of Hookworm-na ve Adults With Dermally-applied Infectious Necator Americanus Hookworm Larvae

An experimental hookworm infection model is being developed to provide early proof-of-concept that a hookworm vaccine targeting the blood-feeding pathway of adult hookworms is feasible and efficacious. The proposed model consists of vaccinating healthy, hookworm-nave adults with a candidate hookworm vaccine, followed by challenging them with the investigational product, Necator …

George Washington University Medical Faculty Associates
 (7.1 away) Contact site
  • 10 Feb, 2020
  • 1 location
VRC 609 Study: A Phase I Open-Label Dose-Escalation Study of the Safety and Pharmacokinetics of a Human Monoclonal Antibody VRC-HIVMAB091-00-AB (N6LS) Administered Intravenously or Subcutaneously With or Without Recombinant Human Hyaluronidase PH...

Background The experimental product in this study, N6LS, is a human monoclonal antibody. Antibodies are one way that the human body fights infection. Monoclonal means that all the antibodies in the product are the same. N6LS is directed against the HIV virus. There is no HIV in the N6LS study …

National Institutes of Health Clinical Center
 (9.7 away) Contact site
  • 07 Jun, 2020
  • 1 location
Research Study Utilizing Expanded Multi-antigen Specific Lymphocytes for the Treatment of Solid Tumors

Patients with high-risk solid tumors, those that are refractory to standard up front therapy or relapse after completion of therapy, have a very poor prognosis despite attempts to induce remission with salvage regimen. Novel therapies are critical for this patient population with high-risk cancer. The ability of tumors to be …

conventional therapy
Children's National Medical Center
 (5.4 away) Contact site
  • 08 Nov, 2020
  • 1 location
Nicotinic Receptor Genetic Variation and Alcohol Reward

Background People with the brain disease AUD (alcohol use disorder) have a serious problem with drinking. Researchers want to study how different people react to alcohol, and how genes affect this. They will focus on a nicotine receptor gene that may increase a person s AUD risk. Objectives To see …

National Institutes of Health Clinical Center
 (9.4 away) Contact site
  • 23 Nov, 2020
  • 1 location