Hyattsville, Maryland Clinical Trials

A listing of Hyattsville, Maryland clinical trials actively recruiting patient volunteers.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 1569 clinical trials
A Study to Assess Whether Macitentan Delays Disease Progression in Children With Pulmonary Arterial Hypertension (PAH)

This is a prospective, multicenter, open-label, randomized, controlled, parallel group, group-sequential, event-driven Phase 3 study to evaluate efficacy, safety and pharmacokinetics (PK) of macitentan in children.

connective tissue disease
macitentan
hypertension
heart disease
Children's National Medical Center
 (5.4 away) Contact site
  • 172 views
  • 29 Nov, 2020
  • +104 other locations
A Study of Bendamustine and Rituximab Alone Versus in Combination With Acalabrutinib in Subjects With Previously Untreated Mantle Cell Lymphoma

This study is evaluating the efficacy of acalabrutinib in combination with bendamustine and rituximab (BR) compared with placebo plus BR in subjects with previously untreated mantle cell lymphoma.

cyclin d1
rituximab
bendamustine
acalabrutinib
Research Site
 (7.8 away) Contact site
  • 1270 views
  • 30 Jul, 2020
  • +212 other locations
Effect of Tumor Treating Fields (TTFields) (150 kHz) Concurrent With Standard of Care Therapies for Treatment of Stage 4 Non-small Cell Lung Cancer (NSCLC) Following Platinum Failure (LUNAR)

The study is a prospective, randomized controlled phase III trial aimed to test the efficacy and safety of TTFields, using the NovoTTF-100L System, concurrent with standard therapies for stage 4 NSCLC patients, following progression while on or after platinum based treatment.The device is an experimental, portable, battery operated device for …

docetaxel
Washington Cancer Institute at MedStar Washington Hospital Center
 (5.4 away) Contact site
  • 644 views
  • 19 Oct, 2020
  • +164 other locations
Study Assessing the Efficacy and Safety of Alpelisib Plus Fulvestrant or Letrozole Based on Prior Endocrine Therapy in Patients With PIK3CA Mutation With Advanced Breast Cancer Who Have Progressed on or After Prior Treatments

Study assessing the efficacy and safety of alpelisib plus fulvestrant or letrozole, based on prior endocrine therapy, in patients with PIK3CA mutation with advanced breast cancer who have progressed on or after prior treatments

measurable disease
gonadotropin releasing hormone
estradiol
advanced breast cancer
endocrine therapy
Holy Cross Hospital Pharmacy
 (6.2 away) Contact site
  • 506 views
  • 19 Aug, 2020
  • +118 other locations
Baroreflex Activation Therapy for Heart Failure

The purpose of this clinical trial (NCT02627196) is to develop valid scientific evidence for safety and effectiveness of Baroreflex Activation Therapy with the BAROSTIM NEO System in subjects with heart failure, defined as New York Heart Association (NYHA) functional Class III, left ventricular ejection fraction (LVEF) 35% and NT-proBNP<1600 pg/ml …

ejection fraction
cardiac resynchronization therapy
medical therapy
diuretics
nt-probnp
George Washington University
 (7.1 away) Contact site
  • 0 views
  • 22 Dec, 2019
  • +121 other locations
Study of OSE2101 Versus Standard Treatment as 2nd or 3rd Line in HLA-A2 Positive Patients With Advanced NSCLC After Failure of Immune Checkpoint Inhibitor

The aim of this study is to determine if the Investigational Medicinal Product Tedopi (OSE2101) is more effective than standard treatment in treating patients with stage IIIB NSCLC unsuitable for radiotherapy or metastatic NSCLC in second- or third-line treatment after failure of immune checkpoint-inhibitor regimens.

stage iv non-small cell lung cancer
secondary malignant neoplasm of liver
neutrophil count
pemetrexed
platinum-based chemotherapy
Georgetown University Hospital
 (7.9 away) Contact site
  • 0 views
  • 16 Dec, 2019
  • +130 other locations
Treatment of Hemochromatosis

This study will evaluate the effectiveness of a test called MCV in guiding phlebotomy (blood drawing) therapy in patients with hemochromatosis an inherited disorder that causes too much iron to be absorbed by the intestine. The excess damages body tissues, most severely in the liver, heart, pancreas and joints. Because …

National Institutes of Health Clinical Center, 9000 Rockville Pike
 (9.7 away) Contact site
  • 4 views
  • 05 Nov, 2020
  • 1 location
Active Reference (Fluoxetine) Fixed-dose Study of Vortioxetine in Paediatric Patients Aged 7 to 11 Years With Major Depressive Disorder (MDD)

Investigation of the efficacy and safety of a new potential treatment of Major depressive disorder (MDD) in paediatric patients (age 7 to 11 years)

major depressive disorder
fluoxetine
vortioxetine
Children's National Medical Center (US1133)
 (5.3 away) Contact site
  • 0 views
  • 02 Aug, 2020
  • +182 other locations
Randomized Trial of the Neochord DS1000 System Versus Open Surgical Repair

The objective of this trial is to assess the safety and effectiveness of the study device in subjects with degenerative mitral valve disease receiving a mitral valve repair without cardiopulmonary bypass (treatment group) when compared to subjects receiving mitral valve repair using standard surgical techniques with cardiopulmonary bypass (control group).

prolapse
cardiopulmonary bypass
mitral valve repair
mitral valve disease
MedStar Washington Hospital Center
 (5.4 away) Contact site
  • 0 views
  • 08 Dec, 2019
  • +16 other locations
Vinblastine +/- Bevacizumab in Children With Unresectable or Progressive Low Grade Glioma (LGG)

This is an open-label, randomized, multi-center, comparator Phase II trial looking at the addition of Bevacizumab to Vinblastine in chemotherapy nave pediatric patients with progressive Low Grade Glioma aged 6 months to less than18 years of age at the time of initiation of therapy. Participants will be randomized to Arm …

auditory test
neutrophil count
vinblastine
progressive disease
BRAF
Children's National Medical Center
 (5.4 away) Contact site
  • 0 views
  • 16 Mar, 2020
  • +22 other locations