Hyattsville, Maryland Clinical Trials

A listing of Hyattsville, Maryland clinical trials actively recruiting patient volunteers.

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Found 1574 clinical trials
Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction

Heart failure with preserved ejection fraction (HFPEF) is common and deadly but without therapy. Inconclusive studies such as TOPCAT (Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist) suggest spironolactone may be effective in HFPEF, but it is generic and will not be studied by industry. SPIRRIT is …

nt-probnp
b-type natriuretic peptide
aldosterone
pro-brain natriuretic peptide
spironolactone
Howard University Hospital
 (5.1 away) Contact site
  • 46 views
  • 06 Jan, 2020
  • +118 other locations
Study of the Efficacy and Safety of Lonafarnib / Ritonavir With and Without Pegylated Interferon -Alfa-2a

Two LNF-containing regimens will be evaluated in the D-LIVR Phase 3 study: (1) LNF/RTV/PEG IFN-alfa-2a and (2) LNF/RTV. Each of these arms will have efficacy endpoints that measure clinical benefit with regard to viral suppression and alanine aminotransferase (ALT) normalization. For each LNF-containing regimen, a composite endpoint of EOT (48 …

National Institutes of Health
 (9.6 away) Contact site
  • 236 views
  • 04 Dec, 2020
  • +170 other locations
Safety Tolerability and Efficacy of Cilofexor in Non-Cirrhotic Adults With Primary Sclerosing Cholangitis

The primary objective of this study is to evaluate whether cilofexor reduces the risk of fibrosis progression among non-cirrhotic adults with primary sclerosing cholangitis (PSC).

fibrosis
platelet count
cilofexor
MedStar Georgetown University Hospital
 (7.9 away) Contact site
  • 83 views
  • 29 Nov, 2020
  • +217 other locations
A Study of DCC-2618 vs Sunitinib in Advanced GIST Patients After Treatment With Imatinib

This is a 2-arm, randomized, open-label, international, multicenter study comparing the efficacy of DCC-2618 to sunitinib in GIST patients who progressed on or were intolerant to first-line anticancer treatment with imatinib. Approximately 426 patients will be randomized in a 1:1 ratio to DCC-2618 150 mg once daily (QD) (continuous dosing …

imatinib
dcc-2618
sunitinib
measurable disease
amylase
Washington Cancer Institute at MedStar Washington Hospital Center
 (5.3 away) Contact site
  • 43 views
  • 28 Oct, 2020
  • +128 other locations
Study of IMMU-132 in HR+/HER2- MBC (TROPICS-02)

This is an open-label, randomized, multicenter Phase 3 study to compare the efficacy and safety of Sacituzumab Govitecan versus TPC in subjects with metastatic or locally recurrent inoperable HR+/HER2- MBC, after failure of at least 2, and no more than 4, prior chemotherapy regimens for metastatic disease.

capecitabine
cancer chemotherapy
kidney function tests
eribulin
HER2
Georgetown University Medical Center
 (7.9 away) Contact site
  • 66 views
  • 05 Oct, 2020
  • +104 other locations
Efficacy Safety and Tolerability of Atogepant for the Prevention of Chronic Migraine

This study will evaluate the efficacy, safety and tolerability of atogepant in participants with chronic migraine. This study includes a 12-week treatment period.

headache
migraine
GW Medical Faculty Associates
 (7.1 away) Contact site
  • 576 views
  • 01 Nov, 2020
  • +146 other locations
A Phase 3 Multi-Center Randomized Double-Blind Placebo-Controlled Study of Fostamatinib Disodium in the Treatment of wAIHA

The primary objective of this study is to assess the efficacy of fostamatinib in subjects with warm antibody autoimmune hemolytic anemia (wAIHA).

Georgetown University
 (7.8 away) Contact site
  • 113 views
  • 26 Oct, 2020
  • +105 other locations
Evaluation of Long Term Safety and Efficacy of Glepaglutide in Treatment of SBS

The primary objective of the trial is to evaluate the long-term safety of glepaglutide treatment in patients with short bowel syndrome (SBS). Glepaglutide is the International Nonproprietary Name and USAN for ZP1848.

Georgetown University Medical Center
 (7.9 away) Contact site
  • 173 views
  • 28 Nov, 2020
  • +50 other locations
Clinical Effect of Ampreloxetine (TD-9855) for Treating Symptomatic nOH in Subjects With Primary Autonomic Failure

A Phase 3 study to evaluate efficacy, safety, and tolerability of ampreloxetine (TD-9855) in subjects with primary autonomic failures (MSA, PD, or PAF) and symptomatic nOH with up to 4 weeks of treatment.

Georgetown University Hospital, Dept. of Neurology
 (7.8 away) Contact site
  • 283 views
  • 04 Dec, 2020
  • +169 other locations
A Study of INCMGA00012 in Metastatic Merkel Cell Carcinoma (POD1UM-201)

The purpose of this study is to assess the clinical activity and safety of INCMGA00012 in participants with advanced/metastatic Merkel cell carcinoma (MCC).

Georgetown University - Lombardi Comprehensive Cancer Center
 (7.9 away) Contact site
  • 21 views
  • 11 Nov, 2020
  • +74 other locations