Creve Coeur, Maryland Clinical Trials

A listing of Creve Coeur, Maryland clinical trials actively recruiting patient volunteers.

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Found 5 clinical trials
Neuroimaging in Healthy Aging and Senile Dementia (HASD IND)

The purpose of this research study is to evaluate the structure and function of the brain in healthy aging and early Alzheimer's disease using positron emission tomography (PET), magnetic resonance imaging (MRI), and computed tomography (CT) imaging. The study involves imaging the brain to detect the presence of amyloid deposits …

alzheimer's disease
senile plaques
pittsburgh compound b
dementia
amyloid
Washington University School of Medicine
 (9.4 away) Contact site
  • 0 views
  • 27 Jul, 2021
  • 1 location
The PROMISE Pediatric Study 6 to 11 Years Old

This is a prospective, multi-center observational study. The study is designed to measure the clinical effectiveness of elexacaftor, tezacaftor and ivacaftor (ETI) triple combination therapy in children (6-11 years of old) with one or more copies of the F508del mutation, study the effects of ETI across a number of CF …

tezacaftor
ivacaftor
fibrosis
elexacaftor
Washington University School of Medicine
 (9.4 away) Contact site
  • 0 views
  • 25 Jul, 2021
  • +19 other locations
Imaging of Brain Structural/Functional Connectivity and Amyloid and Tau Lesions in APOE4 Carriers.

This is a multi-center study at Washington University (WASH U), University of Southern California (USC), and Huntington Medical Research Institute (HMRI).The overall goal of both the AA program and the PPG program is to advance current knowledge on the vascular contributions to dementia particularly in individuals with the major genetic …

flortaucipir
amyloid
apolipoprotein e
dementia
cognitive decline
Washington University School of Medicine
 (9.4 away) Contact site
  • 0 views
  • 30 Jul, 2021
  • 1 location
Cognitive Changes of IDH-mutant and IDH-wildtype Glioma Patients After Chemoradiotherapy With Radiation Dose to the Resting State Networks

Neurocognitive decline after radiation therapy is one of the most concerning complication for brain tumor patients and neuro-oncologists. There are increasing technological advances in evaluating the brain's neural connections responsible for the neurocognitive processes. For example, resting-state functional MRI (RS-fMRI) is an advanced imaging method that can identify the spatiotemporal …

brain tumor
immunohistochemistry
oligodendroglioma
ganglioglioma
karnofsky performance status
Washington University School of Medicine
 (9.4 away) Contact site
  • 0 views
  • 29 Jul, 2021
  • 1 location
Study of Tau Imaging With the Use of [18F]MK-6240 Tracer

The recent development of a PET tracer,[18F]MK-6240(an[18F]tau imaging agent,CerveauTechnologies)that has high affinity for the human phosphorylated tau deposits in AD brain offers new opportunities to investigate tau pathology. The investigators will evaluate this imaging agent in individuals from families with a known Autosomal Dominant Alzheimer's Disease (ADAD) mutation. This study …

alzheimer's disease
dementia
mild dementia
Washington University School of Medicine
 (9.4 away) Contact site
  • 0 views
  • 24 Jul, 2021
  • 1 location