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Waltham, Massachusetts Clinical Trials

A listing of Waltham, Massachusetts clinical trials actively recruiting patient volunteers.

RESULTS

Found (573) clinical trials

An Efficacy and Safety Study of Infliximab Dose Escalation in Pediatric Participants With Inflammatory Bowel Disease

This is a multicenter (when more than one hospital or medical school team work on a medical research study), prospective (study following participants forward in time), open-label (all people know the identity of the intervention) study of infliximab in pediatric participants with inflammatory bowel disease. The study consists of 3 ...

Phase

0.0 miles

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A Phase I Multicenter Open-Label Multi-Part Dose-escalation Study of RAD1901 in Postmenopausal Women With Advanced Estrogen Receptor Positive and HER2-Negative Breast Cancer

The primary objective is to determine the maximum tolerated dose (MTD) and/or recommended Phase 2 dose (RP2D) of elacestrant in patients with advanced ER+HER2-negative breast cancer. The secondary objectives of this study are: To assess the safety and tolerability of elacestrant To evaluate the pharmacokinetics (PK) of elacestrant To evaluate ...

Phase

0.76 miles

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CXL-04 A Study of Collagen Crosslinking With Ultraviolet-A in Asymmetric Corneas

This study will evaluate the results of Corneal Collagen Crosslinking (CXL) in patients with conditions that include Keratoconus, Pellucid Marginal degeneration, Post-LASIK ectasia, and patients with radial keratotomy who experience fluctuation in their vision. This is an outcomes study, all patients receive treatment.

Phase

0.76 miles

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A Phase 3 Study to Evaluate ADX-102 Ophthalmic Solution in Subjects With Non-infectious Anterior-uveitis.

A Phase 3, randomized, double-masked, vehicle-controlled trial to evaluate the safety and efficacy of ADX-102 ophthalmic solution in Subjects with non-infectious anterior-uveitis.

Phase

0.76 miles

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Study to Evaluate the Safety and Efficacy of Epi-on Corneal Cross-linking in Eyes With Progressive Keratoconus

Up to 275 study eyes with progressive keratoconus will be enrolled. Study eyes will be randomized in a 2:1 ratio to receive CXL treatment or sham/control treatment.The primary efficacy endpoint is a difference of 1 diopter between treatment groups in the mean change in Kmax from baseline to Month 6.

Phase

0.76 miles

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A Study of AK002 in Patients With Atopic Keratoconjunctivitis Vernal Keratoconjunctivitis and Perennial Allergic Conjunctivitis

This is a Phase 1b, open-label, study to assess the effects of AK002, given as monthly intravenous infusion, at up to 1 mg/kg for 6 doses.

Phase

0.76 miles

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Evaluation of the Philips Lifeline CareSage Risk Assessment System

The growing elderly population and rising rates of costly chronic disease have led to the development of preventative homecare management opportunities to improve health outcomes and reduce the number of patients who enter costly inpatient care. Partners HealthCare at Home (PHH) is a preventative homecare management system which offers general ...

Phase N/A

0.76 miles

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Using Light Therapy to Treat Toe Nail Fungus

This study is a one year study which includes four treatment sessions of light therapy looking for clinical and mycological improvement.

Phase

1.21 miles

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Cross-linking of Corneal Collagen (CXL) With Ultraviolet-A in Asymmetric Corneas

The purpose of this study is to evaluate the efficacy of ultraviolet-A (UVA)-induced cross-linking of corneal collagen (CXL) as a method to increase the biomechanical and biochemical stability of the cornea by inducing additional cross-links within or between collagen fibers using UVA light and the photo- mediator riboflavin. The purpose ...

Phase N/A

1.6 miles

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Treatment of Adenoviral Conjunctivitis With SHP640 Compared to Povidone-iodine (PVP-I) and Placebo

The purpose of this study is to determine if an investigational treatment is effective compared with placebo and PVP-Iodine in the treatment of adults and children with adenoviral conjunctivitis.

Phase

2.25 miles

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