E Watertown, Massachusetts Clinical Trials

A listing of E Watertown, Massachusetts clinical trials actively recruiting patient volunteers.

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Found 302 clinical trials
Artisan Aphakia Lens for the Correction of Aphakia in Children

The purpose of this study is to determine the safety and effectiveness of the Artisan Aphakia Lens in the treatment of aphakia in children.

Harvard University, Boston Children's Hospital
 (5.2 away) Contact site
  • 26 views
  • 02 Mar, 2021
  • +19 other locations
A Prospective Controlled Treatment Trial for Post-Traumatic Headaches

Post-traumatic headaches (PTH) are the most common complaint after traumatic brain injury, possibly generated by a number of stressors to the trigeminovascular and cervical plexus networks, including inflammation of the high cervical facet joints, traumatic cranial neuralgias, migraines, and myofascial injuries. To date, no treatment guidelines exist for PTH management …

Beth Israel Deaconess Medical Center
 (4.5 away) Contact site
  • 13 views
  • 15 Jun, 2021
  • +1 other locations
Safety and Efficacy Study of ICXP007 With Compression Bandaging for the Treatment of Non-Infected Venous Leg Ulcers

The main purpose of the study is to compare treatment of non-infected venous leg ulcers using ICXP007 combined with four-layer compression bandaging, placebo combined with four-layer compression bandaging and four-layer compression bandaging alone.

ankle brachial pressure index
venous stasis
reflux
arterial disease
compression bandaging
Boston Medical Center, Department of Vascular Surgery
 (6.2 away) Contact site
  • 358 views
  • 07 Nov, 2020
  • +30 other locations
MultiStem Administration for Stroke Treatment and Enhanced Recovery Study

A Phase 3 study to examine the safety and effectiveness of the allogeneic, adult stem cell investigational product, MultiStem, in adults who have suffered an acute ischemic stroke in the previous 18-36 hours.

stroke
Athersys Investigational Site 113
 (6.0 away) Contact site
  • 272 views
  • 16 Sep, 2021
  • +21 other locations
The GUARD Trial - Part 1: A Phase 3 Clinical Trial for Prevention of Proliferative Vitreoretinopathy

The GUARD Trial is a multi-center, randomized, controlled, adaptive Phase 3 clinical trial of repeated intravitreal injections of ADX-2191 versus standard-of-care for the prevention of proliferative vitreoretinopathy.

Massachusetts Eye and Ear
 (6.3 away) Contact site
  • 3 views
  • 28 Jan, 2021
  • +21 other locations
Vitamin D3 With Chemotherapy and Bevacizumab in Treating Patients With Advanced or Metastatic Colorectal Cancer

This phase III trial studies how well vitamin D3 given with standard chemotherapy and bevacizumab works in treating patients with colorectal cancer that has spread to other parts of the body. Vitamin D3 helps the body use calcium and phosphorus to make strong bones and teeth. Drugs used in chemotherapy, …

oxaliplatin
liver metastasis
vitamin d
metastasis
solid tumors
Steward Saint Elizabeth's Medical Center
 (2.0 away) Contact site
  • 83 views
  • 22 Aug, 2021
  • +978 other locations
Study to Investigate the Efficacy and Safety of Dupilumab in Pediatric Patients With Active Eosinophilic Esophagitis (EoE)

The Primary objective is to demonstrate the efficacy of dupilumab treatment compared with placebo in pediatric patients with active eosinophilic esophagitis (EoE) based on histologic improvement meeting validated histologic criteria. The Secondary objectives are: To demonstrate the efficacy of dupilumab compared to placebo in pediatric patients with active EoE after …

Regeneron Study Site
 (6.4 away) Contact site
  • 0 views
  • 26 Sep, 2021
  • +20 other locations
Study of Elafibranor in Patients With Primary Biliary Cholangitis (PBC)

The main objective of the study is to evaluate the effect of daily oral administration of 80mg elafibranor on cholestasis (impairment of bile formation and/or bile accumulation) in patients with PBC and inadequate response or intolerance to Ursodeoxycholic Acid (UCDA)

cholestasis
elafibranor
biopsy of liver
cholangitis
ursodiol
Massachusetts General Hospital
 (6.0 away) Contact site
  • 0 views
  • 15 Sep, 2021
  • +74 other locations
A Study of Osimertinib With or Without Chemotherapy Versus Chemotherapy Alone as Neoadjuvant Therapy for Patients With EGFRm Positive Resectable Non-Small Cell Lung Cancer

This is a Phase III, randomised, controlled, 3-arm, multi-centre study of neoadjuvant osimertinib as monotherapy or in combination with chemotherapy, versus SoC chemotherapy alone, for the treatment of patients with resectable EGFRm Non-Small Cell Lung Cancer

osimertinib
cancer chemotherapy
EGFR
pemetrexed
carboplatin
Research Site
 (2.0 away) Contact site
  • 0 views
  • 12 Sep, 2021
  • +151 other locations
Randomized Study in Children and Adolescents With Migraine: Acute Treatment

The purpose of this study is to test the safety and efficacy of BHV-3000 versus placebo in the acute treatment of moderate or severe migraine in children and adolescents.

erenumab
migraine in children
acute treatment
MedVadis Research Corp
 (4.3 away) Contact site
  • 0 views
  • 27 Sep, 2021
  • +109 other locations