E Watertown, Massachusetts Clinical Trials

A listing of E Watertown, Massachusetts clinical trials actively recruiting patient volunteers.

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Found 305 clinical trials
Multi-Center Study of the Effects of Simvastatin on Hepatic Decompensation and Death in Subjects Presenting With High-Risk Compensated Cirrhosis

This phase III, randomized, double-blind, placebo-controlled, multi-center study seeks to test whether simvastatin, a statin usually used to lower cholesterol to prevent heart problems and strokes, can lower the risk of hepatic decompensation (developing symptoms of cirrhosis) in U.S. Veterans who have compensated cirrhosis (the liver is scarred and damaged …

varices
hypertension
endoscopy
encephalopathy
cirrhosis
VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA
 (5.4 away) Contact site
  • 0 views
  • 26 Aug, 2021
  • +9 other locations
A Study of Lebrikizumab (LY3650150) on Vaccine Response in Adults With Atopic Dermatitis (ADopt-VA)

The reason for this study is to assess the impact of lebrikizumab on vaccine immune response in adult participants with moderate to severe atopic dermatitis (AD).

eczema
topical agents
lebrikizumab
Metro Boston Clinical Partners
 (2.0 away) Contact site
  • 3 views
  • 12 Sep, 2021
  • +95 other locations
RHB-204 for the Treatment of Pulmonary Mycobacterium Avium Complex Disease

A 2-part multi-center, Phase 3, randomized, double-blind, placebo-controlled, parallel group study to evaluate the efficacy and safety of RHB-204 in adult subjects with underlying nodular bronchiectasis and documented MAC lung infection.

respiratory symptom
dyspnea
cough
hemoptysis
Medical Facility
 (6.4 away) Contact site
  • 0 views
  • 18 Aug, 2021
  • +24 other locations
Cryopreserved Human Umbilical Cord (TTAX01) for Late Stage Complex Non-healing Diabetic Foot Ulcers (AMBULATE DFU II)

It is hypothesized that application at 4-week or greater intervals of the human placental umbilical cord tissue TTAX01 to the surface of a well debrided, complex diabetic foot ulcer (DFU) will, with concomitant management of infection, result in a higher rate of wounds showing complete healing within 25 weeks of …

Beth Israel Deaconess Medical Center
 (4.5 away) Contact site
  • 0 views
  • 17 Sep, 2021
  • +21 other locations
Study to Evaluate Viralym-M (ALVR105) for the Treatment of Virus-Associated Hemorrhagic Cystitis (HC)

A study to evaluate ALVR105 (Viralym-M); an allogeneic, off-the-shelf multi-virus specific T cell therapy that targets six viral pathogens: BK virus, cytomegalovirus, adenovirus, Epstein-Barr virus, human herpesvirus 6 and JC virus.

Dana-Farber Cancer Institute
 (4.5 away) Contact site
  • 0 views
  • 09 Aug, 2021
  • +24 other locations
Terlipressin for HRS-AKI in Liver Transplant Candidates (INFUSE)

Hepatorenal syndrome-acute kidney injury (HRS-AKI), a potentially reversible renal failure, is a serious, rapidly progressing, often fatal, complication of decompensated cirrhosis. Terlipressin is a synthetic vasopressin analogue that acts as a systemic vasoconstrictor via the vascular vasopressin V1 receptors. In HRS-AKI patients the strong V1 receptor-mediated vasoconstrictor activity of terlipressin, …

aldosterone
angiotensin
renal failure
ascites
Beth Israel Deaconess Medical Center
 (4.5 away) Contact site
  • 0 views
  • 21 Aug, 2021
  • +5 other locations
A Comparative Study of Sage-217 Plus an Antidepressant (ADT) Versus Placebo Plus an ADT in Adults With Major Depressive Disorder

The primary purpose of this study is to evaluate the efficacy of SAGE-217 plus an ADT in the treatment of major depressive disorder (MDD) compared to placebo plus an ADT.

Sage Investigational Site
 (0.4 away) Contact site
  • 0 views
  • 06 Sep, 2021
  • +46 other locations
Efficacy of Amniotic Suspension Allograft in Patients With Osteoarthritis of the Knee

This study is being conducted to evaluate the efficacy and safety of ASA compared to placebo in the management of osteoarthritis (OA) symptoms of the knee.

analgesics
body mass index
x-rays
Tufts Medical Center
 (6.4 away) Contact site
  • 0 views
  • 17 Jul, 2021
  • +29 other locations
A Study to Assess the Efficacy and Safety of REL-1017 as Adjunctive Treatment for Major Depressive Disorder (MDD)

This is an outpatient, 2-arm, Phase 3, multicenter, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of REL-1017 once daily (QD) as an adjunctive treatment of Major Depressive Disorder. Study participants will continue to take their current antidepressant therapy in addition to the study drug or placebo for …

Relmada Site 117
 (0.4 away) Contact site
  • 56 views
  • 02 Aug, 2021
  • +55 other locations
DuRvalumab With chEmotherapy as First Line treAtment in Advanced Pleural Mesothelioma

Patients with malignant pleural mesothelioma (MPM) that cannot be surgically removed will receive first-line treatment with standard chemotherapy of pemetrexed and cisplatin. Two-thirds of the participants in the study will be randomly assigned to also receive a new treatment called durvalumab. Durvalumab is an antibody (a type of human protein) …

formalin-fixed paraffin-embedded
pleural mesothelioma
gilbert's syndrome
neutrophil count
measurable disease
Dana Farber Cancer Institute
 (4.5 away) Contact site
  • 0 views
  • 06 Sep, 2021
  • +40 other locations