E Watertown, Massachusetts Clinical Trials

A listing of E Watertown, Massachusetts clinical trials actively recruiting patient volunteers.

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Found 2104 clinical trials
Fabry Disease Registry & Pregnancy Sub-registry

The Fabry Registry is an ongoing, international multi-center, strictly observational program that tracks the routine clinical outcomes for patients with Fabry disease, irrespective of treatment status. No experimental intervention is involved; patients in the Registry undergo clinical assessments and receive care as determined by the patient's treating physician. The primary …

agalsidase beta
Investigational Site Number 840092
 (5.2 away) Contact site
  • 05 Apr, 2021
  • +302 other locations
Pompe Disease Registry Protocol

The Pompe Registry is a global, multicenter, international, longitudinal, observational, and voluntary program for patients with Pompe disease, designed to track the disease's natural history and outcomes in patients, both treated and not. Data from the Registry are also used to fulfill various global regulatory commitments, to support product development/reimbursement, …

gaa gene
replacement therapy
alglucosidase alfa
Investigational Site Number 840092
 (5.2 away) Contact site
  • 28 Jan, 2021
  • +279 other locations
Longitudinal Study of Urea Cycle Disorders

Urea cycle disorders (UCD) are a group of rare inherited metabolism disorders. Infants and children with UCD commonly experience episodes of vomiting, lethargy, and coma. The purpose of this study is to perform a long-term analysis of a large group of individuals with various UCDs. The study will focus on …

argininosuccinic aciduria
argininosuccinic acid
Children's Hospital Boston (UCDC New England Center)
 (5.2 away) Contact site
  • 24 Apr, 2021
  • +15 other locations
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

The main purpose of the Product Performance Report (formerly referred to as System Longevity Study) is to evaluate long-term performance of Medtronic market-released cardiac rhythm products by analyzing product survival probabilities.

 (6.3 away) Contact site
  • 23 Sep, 2021
  • +232 other locations
Molecular and Genetic Studies of Congenital Myopathies

In the Congenital Myopathy Research Program at Boston Children's Hospital and Harvard Medical School, the researchers are studying the congenital myopathies (neuromuscular diseases present from birth), including central core disease, centronuclear/myotubular myopathy, congenital fiber type disproportion, multiminicore disease, nemaline myopathy, rigid spine muscular dystrophy, SELENON (SEPN1) and RYR1 myopathy and …

Genetics Division, Boston Children's Hospital
 (5.2 away) Contact site
  • 18 Sep, 2021
  • 1 location
Varying Characteristics of Atherogenesis and Cardiopulmonary Bypass Inflammatory Response

The purpose of this study is to identify possible correlations between phenotypic variation in genes determining atherosclerotic cardiovascular disease (ASCVD), coagulation, and fibrinolysis genetic and plasma markers of chronic inflammation and hypercoagulability with the severity and extent of atherosclerosis, the inflammatory response to cardiac surgery in patients with ASCVD, and …

inflammatory response
cardiovascular disease
atherosclerotic cardiovascular disease
chronic inflammation
Brigham and Women's Hospital
 (5.2 away) Contact site
  • 07 Nov, 2020
  • 1 location
Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network

Background Without an explanation for severe and sometimes life-threatening symptoms, patients and their families are left in a state of unknown. The NIH helped create a network of medical research centers, called the Undiagnosed Diseases Network (UDN), to provide care and answers for these individuals. Objectives To improve diagnosis and …

genetic testing
skin biopsy
Brigham and Women's Hospital
 (5.2 away) Contact site
  • 11 Jun, 2021
  • +23 other locations
GeneMatch: A Program of the Alzheimer's Prevention Registry to Match Individuals to Studies Based on Apolipoprotein E (APOE) Genotype

The purpose of the Alzheimer's Prevention Registry GeneMatch program is to identify a large group of people interested in participating in research studies or clinical trials based in part on their genetic background. This genetic information will be used to match interested individuals to studies, providing a recruitment resource to …

apolipoprotein e
Boston University School of Medicine Alzheimer's Disease Center
 (6.2 away) Contact site
  • 20 Jun, 2021
  • +33 other locations
Pediatric Pulmonary Hypertension Network (PPHNet) Informatics Registry

Patients are being asked to be in this research study because medical researchers hope that by gathering information about a large number of children with pulmonary hypertension over time, their understanding of the disease process will increase and lead to better treatment. Investigators believe that pulmonary hypertension in children is …

Boston Children's Hospital
 (6.3 away) Contact site
  • 10 Jul, 2021
  • +7 other locations
Adolescent Master Protocol for Participants 18 Years of Age and Older (AMP Up)

This is a prospective cohort study designed to define the impact of HIV infection and antiretroviral therapy (ART) on young adults with perinatal HIV infection as they transition into adulthood. A group of perinatally HIV-exposed, -uninfected (PHEU) young adults from a similar sociodemographic background and age distribution will be enrolled …

HIV Infection
opportunistic infection
antiretroviral agents
antiretroviral therapy
Children's Hospital Boston
 (5.2 away) Contact site
  • 01 Sep, 2021
  • +13 other locations