E Watertown, Massachusetts Clinical Trials

A listing of E Watertown, Massachusetts clinical trials actively recruiting patient volunteers.

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Found 2086 clinical trials
Human Epilepsy Genetics--Neuronal Migration Disorders Study

The purpose of this study is to identify genes responsible for epilepsy and disorders of human cognition.

autism
epilepsy
neuronal migration disorders
Children's Hospital Boston, CLS15070, Walsh Lab
 (5.2 away) Contact site
  • 45 views
  • 10 Mar, 2021
  • +1 other locations
Investigation of Anatomical Correlates of Speech Discrimination

Understanding speech is essential for good communication. Individuals with hearing loss and poor speech discrimination often have little success with hearing aids because amplifying sound improves audibility, but not clarity of the speech signal. The purpose of this study is to determine the relative importance of the sensory cells of …

deafness
audiogram
sensorineural hearing loss
fit hearing aid
fitting
Steward St. Elizabeth's Medical Center
 (2.0 away) Contact site
  • 220 views
  • 17 Jun, 2021
  • 1 location
Establishing a Tumor Bank in Families With Multiple Lymphoproliferative Malignancies

The purpose of this study is to investigate possible genetic factors that contribute to the development of lymphomas. The databank will be used to determine whether familial lymphomas have unique genetic characteristics different from sporadic lymphomas and to attempt to identify a gene that confers an increased risk of lymphoma.

lymphoma
hodgkin's disease
chronic lymphocytic leukemia
lymphoproliferative disorder
leukemia
Dana-Farber Cancer Institute
 (5.2 away) Contact site
  • 14 views
  • 25 Jul, 2021
  • 1 location
Mucopolysaccharidosis I (MPS I) Registry

The Mucopolysaccharidosis I (MPS I) Registry is an ongoing, observational database that tracks the outcomes of patients with MPS I. The data collected by the MPS I Registry will provide information to better characterize the natural history and progression of MPS I as well as the clinical responses of patients …

Investigational Site Number 840093
 (5.2 away) Contact site
  • 398 views
  • 30 Mar, 2021
  • +210 other locations
Fabry Disease Registry & Pregnancy Sub-registry

The Fabry Registry is an ongoing, international multi-center, strictly observational program that tracks the routine clinical outcomes for patients with Fabry disease, irrespective of treatment status. No experimental intervention is involved; patients in the Registry undergo clinical assessments and receive care as determined by the patient's treating physician. The primary …

replacement therapy
alpha-galactosidase
fabrazyme
agalsidase beta
deficiency
Investigational Site Number 840092
 (5.2 away) Contact site
  • 456 views
  • 05 Apr, 2021
  • +302 other locations
Pompe Disease Registry Protocol

The Pompe Registry is a global, multicenter, international, longitudinal, observational, and voluntary program for patients with Pompe disease, designed to track the disease's natural history and outcomes in patients, both treated and not. Data from the Registry are also used to fulfill various global regulatory commitments, to support product development/reimbursement, …

myozyme
replacement therapy
alglucosidase alfa
deficiency
gaa gene
Investigational Site Number 840092
 (5.2 away) Contact site
  • 367 views
  • 28 Jan, 2021
  • +279 other locations
Longitudinal Study of Urea Cycle Disorders

Urea cycle disorders (UCD) are a group of rare inherited metabolism disorders. Infants and children with UCD commonly experience episodes of vomiting, lethargy, and coma. The purpose of this study is to perform a long-term analysis of a large group of individuals with various UCDs. The study will focus on …

deficiency
arginine
ornithine
citrullinemia type ii
citrullinemia
Children's Hospital Boston (UCDC New England Center)
 (5.2 away) Contact site
  • 98 views
  • 24 Apr, 2021
  • +15 other locations
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

The main purpose of the Product Performance Report (formerly referred to as System Longevity Study) is to evaluate long-term performance of Medtronic market-released cardiac rhythm products by analyzing product survival probabilities.

 (6.3 away) Contact site
  • 1269 views
  • 22 Aug, 2021
  • +230 other locations
Molecular and Genetic Studies of Congenital Myopathies

In the Congenital Myopathy Research Program at Boston Children's Hospital and Harvard Medical School, the researchers are studying the congenital myopathies (neuromuscular diseases present from birth), including central core disease, centronuclear/myotubular myopathy, congenital fiber type disproportion, multiminicore disease, nemaline myopathy, rigid spine muscular dystrophy, SELENON (SEPN1) and RYR1 myopathy and …

Genetics Division, Boston Children's Hospital
 (5.2 away) Contact site
  • 83 views
  • 15 Sep, 2021
  • 1 location
Varying Characteristics of Atherogenesis and Cardiopulmonary Bypass Inflammatory Response

The purpose of this study is to identify possible correlations between phenotypic variation in genes determining atherosclerotic cardiovascular disease (ASCVD), coagulation, and fibrinolysis genetic and plasma markers of chronic inflammation and hypercoagulability with the severity and extent of atherosclerosis, the inflammatory response to cardiac surgery in patients with ASCVD, and …

inflammatory response
chronic inflammation
atherosclerotic cardiovascular disease
atherosclerosis
cardiovascular disease
Brigham and Women's Hospital
 (5.2 away) Contact site
  • 10 views
  • 07 Nov, 2020
  • 1 location