E Watertown, Massachusetts Clinical Trials

A listing of E Watertown, Massachusetts clinical trials actively recruiting patient volunteers.

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Found 286 clinical trials
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Study of Oral Navitoclax Tablet In Combination With Oral Ruxolitinib Tablet When Compared With Oral Ruxolitinib Tablet To Assess Change In Spleen Volume In Adult Participants With Myelofibrosis

www.MyelofibrosisResearch.com Myelofibrosis is a type of bone marrow cancer that usually develops slowly and disrupts body's normal production of blood cells. It causes bone marrow scarring, leading to severe anemia that can cause weakness and fatigue. It can also cause a low number of blood-clotting cells called platelets, which increases …

Beth Israel Deaconess Medical Center /ID# 224261
 (4.5 away) Contact site
  • 32 views
  • 29 Apr, 2021
  • +148 other locations
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A Study to Evaluate the Efficacy and Safety of Pemigatinib Versus Chemotherapy in Unresectable or Metastatic Cholangiocarcinoma - (FIGHT-302)

The purpose of this study is to evaluate the efficacy and safety of pemigatinib versus gemcitabine plus cisplatin chemotherapy in first-line treatment of participants with unresectable or metastatic cholangiocarcinoma with FGFR2 rearrangement.  

primary cancer
metastatic cancer
cancer
FGFR2
Beth Israel Deaconess Medical Center
 (4.5 away) Contact site
  • 154 views
  • 14 Dec, 2020
  • +154 other locations
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ECOSPOR III: A Phase 3 Multicenter, RandomizeEd, Double Blind, Placebo COntrolled, Parallel Group Study to Evaluate the Safety, Tolerability, & Efficacy of SER-109 vs. Placebo to Reduce Recurrence of ClOstRidium Difficile Infection (CDI) in Adults

ECOSPOR III is a Phase 3, multicenter, randomized, double-blind, placebo-controlled, parallel-group study of the safety, tolerability, and efficacy of SER-109 versus placebo in adult subjects 18 years of age or older with recurrent CDI, defined as: a history of ≥ 3 CDI episodes within 9 months, inclusive of the current …

antibiotic therapy
fidaxomicin
antibiotics
vancomycin
clostridium difficile
Massachusetts General Hospital
 (6.0 away) Contact site
  • 1092 views
  • 21 Dec, 2020
  • +71 other locations
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ECOSPOR IV: An Open-Label Extension of Study SERES-012 and Open-Label Program for Evaluating SER-109 in Adult Subjects with Recurrent Clostridioides difficile Infection (RCDI)

ECOSPOR IV is a Phase 3, multicenter, Open Label study to evaluate the safety and tolerability of SER-109 in adult subjects with recurrent CDI.

clostridium difficile
Beth Israel Deaconess Medical Center
 (4.4 away) Contact site
  • 37 views
  • 21 Dec, 2020
  • +76 other locations
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An Open Label Study to Assess the Safety and Efficacy of COR-003 (2S, 4R ketoconazole) in the Treatment of Endogenous Cushing's Syndrome

An Open Label Study to Assess the Safety and Efficacy of COR-003 (2S, 4R ketoconazole) in the Treatment of Endogenous Cushing's Syndrome

Massachusetts General Hospital
 (6.0 away) Contact site
  • 780 views
  • 25 Mar, 2021
  • +29 other locations
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GRAVITAS-301: A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study of Itacitinib or Placebo in Combination With Corticosteroids for the Treatment of First-Line Acute Graft-Versus-Host Disease

GRAVITAS-301: A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study of Itacitinib or Placebo in Combination With Corticosteroids for the Treatment of First-Line Acute Graft-Versus-Host Disease

graft-versus-host disease
Beth Israel Deaconess Medical Center
 (4.4 away) Contact site
  • 1462 views
  • 08 Dec, 2020
  • +10 other locations
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Corticosteroid Lumbar Epidural Analgesia for Radiculopathy

This is a research study of SP-102, an experimental medication designed to relieve pain in patients with a specific type of leg pain. The mediation is given once by your healthcare professional, with a possibility of a second injection as early as about 1 month after the first treatment. The …

leg pain
sciatica
radicular pain
Semnur Research Site
 (8.1 away) Contact site
  • 1684 views
  • 23 Nov, 2020
  • +23 other locations
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A Phase 2 Study of Sitravatinib in Combination with Nivolumab in Patients with Advanced or Metastatic Urothelial Carcinoma (516-003)

This is a study involving an investigational (experimental) drug called sitravatinib, given in combination with the immunotherapy nivolumab (also known as OPDIVO®).  Sitravatinib is designed to block specific proteins that are thought to cause tumors to grow and to prevent growth of new blood vessels that help cancer tumors to …

nivolumab
tumor cells
platinum-based chemotherapy
advanced urothelial carcinoma
cancer
Dana Farber Cancer Institute
 (4.4 away) Contact site
  • 80 views
  • 02 Jun, 2021
  • +35 other locations
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Intranasal Migraine Treatment Trial

Double-Blind, Randomized, Placebo Controlled, Safety and Efficacy Trial of BHV-3500 (zavegepant) Intranasal (IN) for the Acute Treatment of Migraine

Medvadis Research Corporation
 (4.6 away) Contact site
  • 0 views
  • 10 Jun, 2021
  • +81 other locations
Filgrastim-Mobilized Stem Cells for Transplantation Using Unrelated Donors

The purpose of the study is to: Establish and evaluate a system for collection of filgrastim-mobilized peripheral blood stem cells from National Marrow Donor Program donors (NMDP) donors Assess the safety among NMDP donors of filgrastim administration and PBSC leukapheresis Assess the safety and efficacy of filgrastim-mobilized PBSC in unrelated …

Dana Farber/Partners Cancer Care
 (5.2 away) Contact site
  • 2797 views
  • 21 Mar, 2021
  • +62 other locations