E Watertown, Massachusetts Clinical Trials

A listing of E Watertown, Massachusetts clinical trials actively recruiting patient volunteers.

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Found 285 clinical trials
Sickle Cell Disease and CardiovAscular Risk - Red Cell Exchange Trial (SCD-CARRE)

The SCD-CARRE trial is a Phase 3, prospective, randomized, multicenter, controlled, parallel two-arm study aimed to determine if automated exchange blood transfusion and standard of care administered to high mortality risk adult SCD patients reduces the total number of episodes of clinical worsening of SCD requiring acute health care encounters …

hemoglobin s
blood transfusion
anti-thymocyte globulin
exchange transfusion
sickle hemoglobin
Boston Medical Center
 (6.2 away) Contact site
  • 28 Jul, 2021
  • +14 other locations
Efficacy Safety and Tolerability of Valbenazine for the Treatment of Chorea Associated With Huntington Disease

This is a Phase 3, randomized, double-blind, placebo-controlled study to evaluate the efficacy, safety, and tolerability of valbenazine to treat chorea in subjects with Huntington disease.

Neurocrine Clinical Site
 (6.0 away) Contact site
  • 21 May, 2021
  • +39 other locations
Alvimopan Versus Placebo in Patients Undergoing Radical Cystectomy on an Enhanced Recovery Protocol

To determine if Alvimopan during open or robotic radical cystectomy with urinary diversion results in quicker return of bowel function (GI-2 recovery = time to upper [first toleration of solid food] and lower [first bowel movement] gastrointestinal recovery) compared to placebo.

urinary diversion
ileal conduit
radical cystectomy
Brigham and Women's Hospital
 (5.2 away) Contact site
  • 26 Jul, 2021
  • 1 location
A Study to Evaluate the Efficacy Safety and Drug Concentration of Certolizumab Pegol (CZP) in Children and Adolescent Study Participants With Moderate to Severe Chronic Plaque Psoriasis (PSO)

The purpose of the study is to demonstrate the efficacy and safety of certolizumab pegol in the treatment of moderate to severe chronic plaque psoriasis in study participants aged 6 to 11 and 12 to 17 years.

Ps0007 50158
 (2.0 away) Contact site
  • 17 Jun, 2021
  • +46 other locations
A Study to Evaluate Mavacamten in Adults With Symptomatic Obstructive HCM Who Are Eligible for Septal Reduction Therapy

This is a randomized, double-blind, placebo-controlled, multi-center study in the United States (U.S.) that will evaluate the effect of mavacamten treatment on reducing the number of septal reduction therapy (SRT) procedures performed in subjects with symptomatic obstructive hypertrophic cardiomyopathy (oHCM [also known as HOCM]) who are eligible for SRT based …

Brigham and Women's Hospital
 (4.5 away) Contact site
  • 18 Jun, 2021
  • +17 other locations