E Watertown, Massachusetts Clinical Trials

A listing of E Watertown, Massachusetts clinical trials actively recruiting patient volunteers.

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Found 303 clinical trials
A Trial to Evaluate the Safety Efficacy and Tolerability of Brexpiprazole in Treating Agitation Associated With Dementia of the Alzheimer's Type

This study compares the efficacy of 2 doses of brexpiprazole with placebo in subjects with agitation associated with dementia of the Alzheimer's type.

agitation
dementia
alzheimer's disease
mini-mental state examination
Alzheimer Disease Center
 (6.1 away) Contact site
  • 58 views
  • 01 May, 2021
  • +65 other locations
Mino-Lok Therapy (MLT) for the Treatment of CRBSI/CLABSI

This is a Phase 3, multi-center, randomized, open-label, assess-blind study to determine the efficacy and safety of MLT, a novel antibiotic lock therapy that combines minocycline with edetate disodium in 25% ethanol solution as an adjuctive therapy for the treatment of catheter-related or central line associated bloodstream infection (CRBSI/CLABSI). Approximately …

antibiotics
venipuncture
antibiotic therapy
fever
minocycline
Massachusetts General Hospital
 (6.0 away) Contact site
  • 67 views
  • 11 Jul, 2021
  • +33 other locations
A 12-week Extension Trial to Evaluate the Safety and Tolerability of Brexpiprazole in the Treatment of Subjects With Agitation Associated With Dementia of the Alzheimer's Type

Active treatment extension study of the 331-14-213 trial, to assess the long-term safety and tolerability of oral brexpiprazole as treatment in adult subjects with agitation associated with dementia of the Alzheimer's type (AAD).

agitation
dementia
Alzheimer Disease Center
 (6.1 away) Contact site
  • 21 views
  • 28 Apr, 2021
  • +26 other locations
A Study to Evaluate the Safety of STS101 in the Acute Treatment of Migraine

Study STS101-003 is a multi-center, multiple dose (PRN), open-label, 12-month study to evaluate the safety and tolerability of STS101 (dihydroergotamine nasal powder) in the acute treatment of migraine.

acute treatment
dihydroergotamine
headache
Medvadis Research at Boston PainCare Center
 (4.3 away) Contact site
  • 303 views
  • 09 Sep, 2021
  • +42 other locations
Stereotactic Body Radiation Therapy (SBRT) vs Trans-Arterial Chemoembolization (TACE) as Bridge to Transplant

This study will compare stereotactic body radiation therapy (SBRT) to trans-arterial chemoembolization (TACE) as a bridging strategy for patients with HCC undergoing liver transplantation. We propose that SBRT will be associated with longer time intervals between initial treatment and the need for retreatment, compared to TACE, as a "bridge" to …

liver transplant
chemoembolization
stereotactic body radiation therapy
hepatoma
TACE
Lahey Hospital & Medical Center
 (8.1 away) Contact site
  • 0 views
  • 23 Sep, 2021
  • 1 location
Testing the Addition of the Drug Atezolizumab to the Usual Radiation Treatment for Patients With Early Non-small Cell Lung Cancer

This trial studies how well atezolizumab added to the usual radiation therapy works in treating patients with stage I-IIA non-small cell lung cancer. Immunotherapy with monoclonal antibodies, such as atezolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow …

kidney function test
ct scan
stereotactic body radiation therapy
neutrophil count
atezolizumab
Lahey Hospital and Medical Center
 (8.1 away) Contact site
  • 0 views
  • 23 Sep, 2021
  • +148 other locations
A Multi-Site Phase 3 Study of MDMA-Assisted Psychotherapy for PTSD

Posttraumatic stress disorder (PTSD) is a debilitating psychiatric disorder that can develop after a traumatic life experience that severely reduces quality of life. This multi-site, double-blind, placebo-controlled, randomized Phase 3 study will assess the efficacy and safety of 3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy compared to psychotherapy with placebo in participants diagnosed with …

psychotherapy
mdma
suicidal
psychiatric disorder
Trauma Research Foundation
 (3.6 away) Contact site
  • 807 views
  • 28 Jun, 2021
  • +14 other locations
A Study to Evaluate Mavacamten in Adults With Symptomatic Obstructive HCM Who Are Eligible for Septal Reduction Therapy

This is a randomized, double-blind, placebo-controlled, multi-center study in the United States (U.S.) that will evaluate the effect of mavacamten treatment on reducing the number of septal reduction therapy (SRT) procedures performed in subjects with symptomatic obstructive hypertrophic cardiomyopathy (oHCM [also known as HOCM]) who are eligible for SRT based …

Brigham and Women's Hospital
 (4.5 away) Contact site
  • 0 views
  • 16 Sep, 2021
  • +17 other locations
RAndomized Therapy In Status Epilepticus

This study will evaluate the effectiveness and safety of an investigational product, IV ganaxolone, to treat subjects with status epilepticus.

status epilepticus
Marinus Research Site
 (6.2 away) Contact site
  • 0 views
  • 17 Jun, 2021
  • +51 other locations
Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

This phase III trial compares the effect of bevacizumab and osimertinib combination vs. osimertinib alone for the treatment of non-small cell lung cancer that has spread outside of the lungs (stage IIIB-IV) and has a change (mutation) in a gene called EGFR. The EGFR protein is involved in cell signaling …

Winchester Hospital
 (6.1 away) Contact site
  • 0 views
  • 23 Sep, 2021
  • +382 other locations