E Watertown, Massachusetts Clinical Trials

A listing of E Watertown, Massachusetts clinical trials actively recruiting patient volunteers.

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Found 305 clinical trials
Study to Evaluate Viralym-M (ALVR105) for the Treatment of Virus-Associated Hemorrhagic Cystitis (HC)

A study to evaluate ALVR105 (Viralym-M); an allogeneic, off-the-shelf multi-virus specific T cell therapy that targets six viral pathogens: BK virus, cytomegalovirus, adenovirus, Epstein-Barr virus, human herpesvirus 6 and JC virus.

Dana-Farber Cancer Institute
 (4.5 away) Contact site
  • 09 Aug, 2021
  • +24 other locations
Terlipressin for HRS-AKI in Liver Transplant Candidates (INFUSE)

Hepatorenal syndrome-acute kidney injury (HRS-AKI), a potentially reversible renal failure, is a serious, rapidly progressing, often fatal, complication of decompensated cirrhosis. Terlipressin is a synthetic vasopressin analogue that acts as a systemic vasoconstrictor via the vascular vasopressin V1 receptors. In HRS-AKI patients the strong V1 receptor-mediated vasoconstrictor activity of terlipressin, …

renal failure
Beth Israel Deaconess Medical Center
 (4.5 away) Contact site
  • 21 Aug, 2021
  • +5 other locations
A Comparative Study of Sage-217 Plus an Antidepressant (ADT) Versus Placebo Plus an ADT in Adults With Major Depressive Disorder

The primary purpose of this study is to evaluate the efficacy of SAGE-217 plus an ADT in the treatment of major depressive disorder (MDD) compared to placebo plus an ADT.

Sage Investigational Site
 (0.4 away) Contact site
  • 06 Sep, 2021
  • +46 other locations
Efficacy of Amniotic Suspension Allograft in Patients With Osteoarthritis of the Knee

This study is being conducted to evaluate the efficacy and safety of ASA compared to placebo in the management of osteoarthritis (OA) symptoms of the knee.

body mass index
Tufts Medical Center
 (6.4 away) Contact site
  • 17 Jul, 2021
  • +29 other locations
A Study to Assess the Efficacy and Safety of REL-1017 as Adjunctive Treatment for Major Depressive Disorder (MDD)

This is an outpatient, 2-arm, Phase 3, multicenter, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of REL-1017 once daily (QD) as an adjunctive treatment of Major Depressive Disorder. Study participants will continue to take their current antidepressant therapy in addition to the study drug or placebo for …

Relmada Site 117
 (0.4 away) Contact site
  • 02 Aug, 2021
  • +55 other locations
DuRvalumab With chEmotherapy as First Line treAtment in Advanced Pleural Mesothelioma

Patients with malignant pleural mesothelioma (MPM) that cannot be surgically removed will receive first-line treatment with standard chemotherapy of pemetrexed and cisplatin. Two-thirds of the participants in the study will be randomly assigned to also receive a new treatment called durvalumab. Durvalumab is an antibody (a type of human protein) …

neutrophil count
pleural mesothelioma
formalin-fixed paraffin-embedded
measurable disease
Dana Farber Cancer Institute
 (4.5 away) Contact site
  • 06 Sep, 2021
  • +40 other locations
A Study of Baricitinib (LY3009104) in Participants With Moderate to Severe Atopic Dermatitis

This open-label study will evaluate the long-term efficacy and safety of baricitinib in adult participants with moderate to severe atopic dermatitis (AD).

topical agents
Brigham and Women's Hospital
 (4.5 away) Contact site
  • 12 Sep, 2021
  • +76 other locations
Ravulizumab and COVID-19

Ultomiris (Ravulizumab), is a monoclonal antibody that specifically targets terminal complement products and is proposed for the treatment of COVID-19 induced microvasculature injury and endothelial damage leading to thrombotic microangiopathy (TMA) causing acute kidney injury (AKI). Ravulizumab is to be used for participants with a confirmed diagnosis of COVID-19 who …

Brigham and Women's Hospital
 (4.5 away) Contact site
  • 29 Jan, 2021
  • 1 location
A Clinical Trial to Assess the Agent Paclitaxel Coated PTCA Balloon Catheter for the Treatment of Subjects With In-Stent Restenosis (ISR)

AGENT IDE is a Prospective, Randomized (2:1), Multicenter Trial. The purpose of this study is to assess the safety and effectiveness of the Agent Paclitaxel Coated PTCA Balloon Catheter compared to balloon angioplasty (POBA) in patients with in-stent restenosis (ISR) of a previously treated lesion of up to 26 mm …

Beth Israel Deaconess Medical Center
 (4.5 away) Contact site
  • 15 Sep, 2021
  • +10 other locations
PH94B Nasal Spray for Anxiety Induced by a Public Speaking Challenge

This Phase 3 clinical trial is designed to evaluate the efficacy, safety, and tolerability of the acute administration of 3.2 g of PH94B to relieve symptoms of anxiety in adult subjects with social anxiety disorder (SAD) during an induced public speaking challenge. Subject participation in the Study will last a …

VistaGen Clinical Site
 (0.4 away) Contact site
  • 03 Sep, 2021
  • +13 other locations