E Watertown, Massachusetts Clinical Trials

A listing of E Watertown, Massachusetts clinical trials actively recruiting patient volunteers.

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Found 302 clinical trials
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Study of Oral Navitoclax Tablet In Combination With Oral Ruxolitinib Tablet When Compared With Oral Ruxolitinib Tablet To Assess Change In Spleen Volume In Adult Participants With Myelofibrosis

www.MyelofibrosisResearch.com Myelofibrosis is a type of bone marrow cancer that usually develops slowly and disrupts body's normal production of blood cells. It causes bone marrow scarring, leading to severe anemia that can cause weakness and fatigue. It can also cause a low number of blood-clotting cells called platelets, which increases …

Beth Israel Deaconess Medical Center /ID# 224261
 (4.5 away) Contact site
  • 83 views
  • 29 Apr, 2021
  • +148 other locations
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A Study to Evaluate the Efficacy and Safety of Pemigatinib Versus Chemotherapy in Unresectable or Metastatic Cholangiocarcinoma - (FIGHT-302)

The purpose of this study is to evaluate the efficacy and safety of pemigatinib versus gemcitabine plus cisplatin chemotherapy in first-line treatment of participants with unresectable or metastatic cholangiocarcinoma with FGFR2 rearrangement.  

FGFR2
metastatic cancer
primary cancer
cancer
Beth Israel Deaconess Medical Center
 (4.5 away) Contact site
  • 173 views
  • 25 Aug, 2021
  • +145 other locations
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ECOSPOR IV: An Open-Label Extension of Study SERES-012 and Open-Label Program for Evaluating SER-109 in Adult Subjects with Recurrent Clostridioides difficile Infection (RCDI)

ECOSPOR IV is a Phase 3, multicenter, Open Label study to evaluate the safety and tolerability of SER-109 in adult subjects with recurrent CDI.

clostridium difficile
Beth Israel Deaconess Medical Center
 (4.4 away) Contact site
  • 41 views
  • 21 Dec, 2020
  • +76 other locations
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ECOSPOR III: A Phase 3 Multicenter, RandomizeEd, Double Blind, Placebo COntrolled, Parallel Group Study to Evaluate the Safety, Tolerability, & Efficacy of SER-109 vs. Placebo to Reduce Recurrence of ClOstRidium Difficile Infection (CDI) in Adults

ECOSPOR III is a Phase 3, multicenter, randomized, double-blind, placebo-controlled, parallel-group study of the safety, tolerability, and efficacy of SER-109 versus placebo in adult subjects 18 years of age or older with recurrent CDI, defined as: a history of ≥ 3 CDI episodes within 9 months, inclusive of the current …

antibiotics
clostridium difficile
fidaxomicin
antibiotic therapy
vancomycin
Massachusetts General Hospital
 (6.0 away) Contact site
  • 1107 views
  • 21 Dec, 2020
  • +71 other locations
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An Open Label Study to Assess the Safety and Efficacy of COR-003 (2S, 4R ketoconazole) in the Treatment of Endogenous Cushing's Syndrome

An Open Label Study to Assess the Safety and Efficacy of COR-003 (2S, 4R ketoconazole) in the Treatment of Endogenous Cushing's Syndrome

Massachusetts General Hospital
 (6.0 away) Contact site
  • 786 views
  • 25 Mar, 2021
  • +29 other locations
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GRAVITAS-301: A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study of Itacitinib or Placebo in Combination With Corticosteroids for the Treatment of First-Line Acute Graft-Versus-Host Disease

GRAVITAS-301: A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study of Itacitinib or Placebo in Combination With Corticosteroids for the Treatment of First-Line Acute Graft-Versus-Host Disease

graft-versus-host disease
Beth Israel Deaconess Medical Center
 (4.4 away) Contact site
  • 1462 views
  • 08 Dec, 2020
  • +10 other locations
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Intranasal Migraine Treatment Trial

Double-Blind, Randomized, Placebo Controlled, Safety and Efficacy Trial of BHV-3500 (zavegepant) Intranasal (IN) for the Acute Treatment of Migraine

Medvadis Research Corporation
 (4.6 away) Contact site
  • 14 views
  • 10 Jun, 2021
  • +81 other locations
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A Phase 2 Study of Sitravatinib in Combination with Nivolumab in Patients with Advanced or Metastatic Urothelial Carcinoma (516-003)

This is a study involving an investigational (experimental) drug called sitravatinib, given in combination with the immunotherapy nivolumab (also known as OPDIVO®).  Sitravatinib is designed to block specific proteins that are thought to cause tumors to grow and to prevent growth of new blood vessels that help cancer tumors to …

metastatic urothelial carcinoma
platinum-based chemotherapy
urothelial carcinoma
advanced urothelial cancer
nivolumab
Dana Farber Cancer Institute
 (4.4 away) Contact site
  • 80 views
  • 02 Jun, 2021
  • +35 other locations
Assess the Long Term Efficacy and Safety of Ruxolitinib Cream in Participants With Vitiligo

The purpose of this study is to evaluate the duration of response following withdrawal of ruxolitinib cream (Cohort A vehicle group), safety and maintenance of response with continued use of ruxolitinib cream in participants who have completed either Study NCT04052425 or NCT04057573 (parent studies) in which the participants will have …

Metro Boston Clinical Partners
 (2.0 away) Contact site
  • 182 views
  • 04 Jul, 2021
  • +83 other locations
Study to Assess the Efficacy Safety and Tolerability of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type

This study will be conducted to evaluate the efficacy, safety, and tolerability of AVP-786 (deudextromethorphan hydrobromide [d6-DM]/quinidine sulfate [Q]) compared to placebo for the treatment of agitation in participants with dementia of the Alzheimer's type.

Clinical Research Site
 (4.7 away) Contact site
  • 0 views
  • 02 Sep, 2021
  • +37 other locations