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Brookline, Massachusetts Clinical Trials

A listing of Brookline, Massachusetts clinical trials actively recruiting patient volunteers.

RESULTS

Found (777) clinical trials

Gout: Allopurinol vs. Febuxostat

Gout is the most common form of inflammatory arthritis affecting adults (1), with a disease frequency that continues to increase dramatically (2). Gout is associated with substantial morbidity and mortality which are concentrated in older men and magnified in patients with chronic kidney disease (CKD) (3-6), demographics common to the ...

Phase

1.48 miles

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Neurohormonal Benefits of Exercise in Fibromyalgia and PTSD

This study will compare the effects of a 12-week progressive exercise training program on 1) Fibromyalgia (FM) pain and PTSD symptoms, 2) pain threshold and tolerance, and 3) relevant biomarkers and neuromodulators including: a) anti-stress, anti-nociceptive, immune modulating factors such as neuropeptide Y (NPY) and GABAergic neuroactive steroids such as ...

Phase N/A

1.48 miles

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Low Dose Naltrexone for Chronic Pain From Arthritis

Chronic pain affects over 100 million Americans, and arthritis is the most common cause. Existing treatments for chronic arthritic pain are only mildly effective, and risks of medications used to treat pain are numerous and continue to be discovered. Treatment of chronic is a high priority research area for VA ...

Phase

1.48 miles

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Exercise Therapy to Reduce Heart Failure Symptoms; Sorting Mechanisms of Benefit

Despite decades of research, heart failure (HF) remains a common disease that continues to rise in prevalence, particularly among an expanding senior population. By virtue of age, older adults are prone to higher incidence of HF and worse clinical consequences. Exercise intolerance and dyspnea are common symptoms that portend poor ...

Phase N/A

1.48 miles

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Recovering From Intimate Partner Violence Through Strengths and Empowerment (RISE)

Women are the fastest growing group of VHA patients, with their population recently increasing by 80%. Women Veterans (WV's) are at higher risk for IPV than their non-Veteran peers, with that 1 in 3 WVs report lifetime IPV, compared to 1 in 4 women in the general U.S. population. Research ...

Phase

1.48 miles

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Tai Chi and Wellness Education for Older Veterans

The proposed study will consist of a pilot trial of three 12-week, 24-session Tai Chi intervention groups compared with three 12-week, 24-session wellness education control groups. Participants will be randomly assigned in blocks of 14 to either the Tai Chi or the wellness education condition, half to each. Veterans who ...

Phase N/A

1.48 miles

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Exercise Training to Improve Cognitive Function

Background/Rationale: Alzheimer's disease (AD) afflicts nearly 6 million Americans, a number projected to grow in coming decades. AD is known to have a long preclinical phase in which pathophysiologic processes develop many years, even decades, before the onset of clinical symptoms. During this preclinical phase there is evidence of unremitting ...

Phase

1.48 miles

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Computer Aided Detection of Polyps in the Colon

Length of Study - The duration of the study is expected to be 8-12 months. Enrollment of study patients will cease when approximately 250 patients have been enrolled. Study Design- Design will be a multi-center, prospective, unblinded randomized control trial. Patients referred for either screening or surveillance colonoscopy will be ...

Phase N/A

1.48 miles

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Decentralized Dietary UC Pilot Trial

This study is designed to assess differences in remote and on-site patient study participation in the State of Massachusetts, as well as the significance of dietary interventions and their impact on UC. The study will activate one site with a Principal Investigator who will utilize each subject's local care system ...

Phase N/A

1.56 miles

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Integrative Migraine Pain Alleviation Through Chiropractic Therapy

Chiropractic care is a commonly used therapeutic intervention for the treatment of pain disorders, and some smaller studies have shown that it might be helpful for migraines. This pilot study will use a comprehensive model of chiropractic treatment which can include soft tissue mobilization, spinal manipulation, and postural and spinal ...

Phase N/A

1.56 miles

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