Brookline, Massachusetts Clinical Trials

A listing of Brookline, Massachusetts clinical trials actively recruiting patient volunteers.

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Found 1915 clinical trials
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Fox Insight - Online Parkinson's Health and Genetic Study

Fox Insight is an online study gathering health information from tens of thousands of people with and without Parkinson’s disease.  Study participation does not require any travel and all you need is an internet connection to start today at www.foxinsight.org Fox Insight volunteers are invited to take part in virtual …

www.foxinsight.org
 (3.5 away) Contact site
  • 3557 views
  • 29 Mar, 2021
  • +333 other locations
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GRAVITAS-301: A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study of Itacitinib or Placebo in Combination With Corticosteroids for the Treatment of First-Line Acute Graft-Versus-Host Disease

GRAVITAS-301: A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study of Itacitinib or Placebo in Combination With Corticosteroids for the Treatment of First-Line Acute Graft-Versus-Host Disease

graft-versus-host disease
Beth Israel Deaconess Medical Center
 (2.2 away) Contact site
  • 1462 views
  • 08 Dec, 2020
  • +10 other locations
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An Open Label Study to Assess the Safety and Efficacy of COR-003 (2S, 4R ketoconazole) in the Treatment of Endogenous Cushing's Syndrome

An Open Label Study to Assess the Safety and Efficacy of COR-003 (2S, 4R ketoconazole) in the Treatment of Endogenous Cushing's Syndrome

Massachusetts General Hospital
 (4.5 away) Contact site
  • 780 views
  • 25 Mar, 2021
  • +29 other locations
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A Phase 2 Study of Sitravatinib in Combination with Nivolumab in Patients with Advanced or Metastatic Urothelial Carcinoma (516-003)

This is a study involving an investigational (experimental) drug called sitravatinib, given in combination with the immunotherapy nivolumab (also known as OPDIVO®).  Sitravatinib is designed to block specific proteins that are thought to cause tumors to grow and to prevent growth of new blood vessels that help cancer tumors to …

metastatic urothelial carcinoma
advanced urothelial carcinoma
platinum-based chemotherapy
tumor cells
cancer
Dana Farber Cancer Institute
 (2.2 away) Contact site
  • 80 views
  • 02 Jun, 2021
  • +35 other locations
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A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients With Advanced Solid Tumors With KRAS G12C Mutation

Evaluates the safety, tolerability, pharmacokinetics, metabolites, pharmacodynamics, and clinical activity of MRTX849 in patients with advanced solid tumors with a KRAS G12C mutation. MRTX849 is an orally-available small molecule inhibitor of KRAS G12C.

solid tumor
malignant solid tumor
advanced solid tumor
Mirati Research Site
 (2.3 away) Contact site
  • 405 views
  • 08 Jul, 2021
  • +72 other locations
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A Phase 1/2 Trial of MRTX849 in Combination with TNO155 in Patients with Advanced Solid Tumors with KRAS G12C Mutation

Characterize the safety and tolerability, and evaluate Pharmacokinetics of MRTX849 in combination with TNO155 in patients with advanced solid tumor malignancies with KRAS G12C mutation. MRTX849 is an orally available small molecute inhibitor of KRASG12C. TNO155 is a selective, orally bioavailable allosteric inhibitor of wild type SHP2.

solid tumor
solid tumors
malignant solid tumor
advanced solid tumor
Dana Farber
 (2.2 away) Contact site
  • 114 views
  • 19 Feb, 2021
  • +9 other locations
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Caregiver-Provided Life Review for Persons with Dementia in Care Facilities

Five percent of community‐dwelling older Americans experience depression. The rate is higher among persons with dementia (30%). One in 10 older adults (5.6 million) had Alzheimer’s dementia in 2019 and 70% are cared for by their families. This public health issue will worsen as the aging baby boomers grow from …

dementia
depression
Online253
 (3.1 away) Contact site
  • 208 views
  • 07 Jul, 2021
  • +252 other locations
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[Online] The Neureka Project

The Neureka Project aims to develop new ways of detecting disorders of the brain early. From mental health conditions to dementia, we want to find out who is at risk and why, so we can develop preventative interventions that can be used the world over. To do this, we are taking …

[Online] The Neureka Project
 (3.5 away) Contact site
  • 0 views
  • 29 Apr, 2021
  • +240 other locations
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We are currently recruiting participants for the BLUEPRINT study. This study investigates the effectiveness, safety, and tolerability of the drug BLU-5937 for chronic itch in people with eczema.

The BLUEPRINT study consists of taking two tablets orally, twice a day, for a period of 4 weeks. This treatment is experimental. You will have 50% chance to receive BLU-5937 and 50% chance to receive the placebo. There will be a total of 5 visits at the clinic and 2 …

adult atopic dermatitis
dermatitis
atopic dermatitis
eczema
atopic dermatitis/eczema
Beacon Clinical Research
 (8.6 away) Contact site
  • 0 views
  • 10 Dec, 2020
  • +24 other locations
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[Remote] The Impact of Emotions on Social Distancing Adherence and Caregiver Self-efficacy among Caregivers for individuals with Alzheimer’s disease or related dementias during the COVID-19 Pandemic

The purpose of this research study is to understand the factors (e.g., feeling unhappy, lonely, frustrated) that influence compliance with social distancing recommendations during the COVID-19 pandemic. In addition, this study aims to understand how negative emotions (e.g., feeling unhappy, lonely, frustrated) along with social distancing requirements influence family caregivers’ …

[Remote] The Impact of Emotions on Social Distancing Adherence and Caregiver Self-efficacy among Caregivers for individuals with Alzheimer’s disease or related dementias during the COVID-19 Pandemic
 (3.5 away) Contact site
  • 0 views
  • 29 Apr, 2021
  • +243 other locations