Brookline, Massachusetts Clinical Trials

A listing of Brookline, Massachusetts clinical trials actively recruiting patient volunteers.

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Found 1915 clinical trials
Pyruvate Kinase (PK) Deficiency Global Longitudinal Registry: Patient-Reported Outcomes (PRO)

The primary objective of this study is to understand and characterize the health-related quality of life (HRQoL) and disease burden of adult participants with PK deficiency receiving routine clinical care. This study is an observational (i.e., noninterventional), longitudinal, multicenter, global registry for participants with PK deficiency, a rare nonspherocytic hemolytic …

anemia
Massachusetts General Hospital
 (4.5 away) Contact site
  • 0 views
  • 25 Jul, 2021
  • 1 location
Early Longitudinal Imaging in Parkinson's Progression Markers Initiative Using [ F] AV-133 and DaTscan

Directly examine whether early (6-month) imaging with DaTscan and [F] AV-133 will provide an early signal of disease progression in recently diagnosed untreated PD patients.

positron emission tomography
datscan
Boston University Medical Center
 (3.3 away) Contact site
  • 0 views
  • 28 Jan, 2021
  • +2 other locations
Sensory and Connectivity Abnormalities in Autism Spectrum Disorders

Study the neural substrates of autism spectrum disorders using neuroimaging methods such as MEG/EEG/MRI.

pervasive developmental disorder
autism
language disorder
Martinos Center or Biomedical Imaging
 (5.1 away) Contact site
  • 0 views
  • 25 Jan, 2021
  • 1 location
Neurofilament Surveillance Project (NSP)

This is a biomarker study designed to collect and analyze blood specimens from individuals carrying known familial frontotemporal lobar degeneration (f-FTLD) mutations compared to a control group of individuals without known f-FTLD mutations. The NSP is an ancillary study to the ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration" (ALLFTD) study, NCT04363684. …

frontotemporal lobar degeneration
Massachusetts General Hospital
 (5.1 away) Contact site
  • 12 views
  • 03 Jul, 2021
  • +7 other locations
Study of Gastrointestinal Dysfunction and Enteric Neural Pathology in Patients With Parkinson's Disease

The goal of this research is to determine (1) the feasibility of tethered capsule OCT esophageal imaging in the Parkinson's Disease population; (2) the morphologic changes in the enteric nervous system of the esophagus in patients with Parkinson's disease.

Massachusetts General Hospital
 (4.5 away) Contact site
  • 0 views
  • 25 Jan, 2021
  • 1 location
Immune Response to SARS-CoV-2 (COVID-19) Vaccines in Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

This study evaluates the immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines in patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). CLL and SLL are types of blood cancer that begin in cells of the immune system. CLL/SLL and the medications used to treat …

lymphoma
chronic lymphocytic leukemia
cancer
Dana-Farber Cancer Center
 (2.3 away) Contact site
  • 0 views
  • 21 Jul, 2021
  • +18 other locations
Tracking Response to Antidepressants in Advance of Investigational Trials

TRAIT is an open-label observational study to evaluate treatment response to selective-serotonin reuptake inhibitors (SSRIs) and selective-norepinephrine reuptake inhibitors (SNRIs) among individuals meeting criteria for Major Depressive Disorder (MDD) and seeking enrollment in investigational trials.

Adams Clinical
 (3.7 away) Contact site
  • 0 views
  • 19 Mar, 2021
  • 1 location
Telemedicine Abdominal Exams & Imaging

A study of patients with abdominal pain being seen by physicians at an academic emergency department and by physicians who are based remotely (telehealth). Hypothesis: When a patient with abdominal pain is examined by a physician at the hospital versus a physician who is remote (i.e. not at the hospital), …

Massachusetts General Hospital
 (4.5 away) Contact site
  • 0 views
  • 05 Mar, 2021
  • 1 location
Breath Biomarkers for Sleep Loss and Circadian Timing

Insufficient sleep has both health and safety risks, but currently there are no quick, accurate and inexpensive ways to measure sleep deficiency. The current study aims to use a cutting-edge technology, small molecule analysis (e.g. metabolomics), to detect compounds in breath that reliably change with sleep-wake state and those whose …

Brigham and Women's Hospital
 (2.3 away) Contact site
  • 0 views
  • 08 Jul, 2021
  • 1 location
Developing a Test for the Detection of Ovarian Cancer

The study aims to develop a test for early detection of ovarian cancer using DNA from a growth involving the ovary found in a washing of the uterus (womb), and proteins found in the blood. The samples of the wash and the blood will be taken before surgery. After surgery, …

Massachusetts General Hospital
 (4.5 away) Contact site
  • 0 views
  • 24 Mar, 2021
  • +5 other locations