Brookline, Massachusetts Clinical Trials

A listing of Brookline, Massachusetts clinical trials actively recruiting patient volunteers.

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Found 2050 clinical trials
Longitudinal Study of the Porphyrias

The objective of this protocol is to conduct a longitudinal multidisciplinary investigation of the human porphyrias including the natural history, morbidity, pregnancy outcomes, and mortality in people with these disorders.

Massachusetts General Hospital
 (4.5 away) Contact site
  • 26 Jan, 2021
  • +14 other locations
Genetics of Severe Early Onset Epilepsies

Investigators at Boston Children's Hospital are conducting research in order to better understand the genetic factors which may contribute to disorders related to epilepsy. These findings may help explain the broad spectrum of clinical characteristics and outcomes seen in people with epilepsy.

Boston Children's Hospital
 (2.5 away) Contact site
  • 05 Aug, 2021
  • 1 location
Genetic Studies of Strabismus Congenital Cranial Dysinnervation Disorders (CCDDs) and Their Associated Anomalies

The purpose of this study is to identify genes associated with impaired development and function of the cranial nerves and brainstem, which may result in misalignment of the eyes (strabismus) and related conditions.

Boston Children's Hospital
 (2.5 away) Contact site
  • 15 Sep, 2021
  • 1 location
Prospective Global Registry for the Study of Chronic Total Occlusion Intervention

Percutaneous coronary intervention (PCI) of chronic total occlusions (CTOs) is increasingly being performed in patients with advanced coronary artery disease, but there is limited information on the techniques utilized and the procedural outcomes. The goal of this multicenter, investigator initiated registry is to collect information on treatment strategies and outcomes …

arterial disease
percutaneous coronary intervention
Beth Israel Deaconess Medical Center
 (2.3 away) Contact site
  • 14 Mar, 2021
  • +47 other locations
Lysosomal Acid Lipase (LAL) Deficiency Registry

This is an observational, multi-center, international disease registry designed to collect longitudinal data and create a knowledge base that will be utilized to improve the care and treatment of patients with LAL Deficiency. Participation in the Registry by both physicians and patients is voluntary.

 (2.5 away) Contact site
  • 01 Feb, 2021
  • +27 other locations
Natural History Study of Synucleinopathies

Synucleinopathies are a group of rare diseases associated with worsening neurological deficits and the abnormal accumulation of the protein -synuclein in the nervous system. Onset is usually in late adulthood at age 50 or older. Usually, synucleinopathies present clinically with slowness of movement, coordination difficulties or mild cognitive impairment. Development …

mild cognitive impairment
sexual dysfunction
lewy body dementia
Beth Israel Deaconess Medical Center
 (4.5 away) Contact site
  • 05 Feb, 2021
  • +9 other locations
Parkinson's Foundation Quality Improvement Initiative

In a recent study it was found that neurologist care for Parkinson's provides a 20% reduction in nursing home placement, hip fracture, and death (Willis 2011). However, as the authors recognized, the investigators don't know what it is about expert care that delivers this benefit. The Parkinson's Foundation's Quality Improvement …

Beth Israel Deaconess Medical Center Parkinson's Disease Movement Disorder Center
 (4.5 away) Contact site
  • 23 Jan, 2021
  • +23 other locations
DECAMP-2: Screening of Patients With Early Stage Lung Cancer or at High Risk for Developing Lung Cancer

The goal of this project is to improve lung cancer screening in high-risk individuals by identifying biomarkers of preclinical disease and disease risk that are measured in minimally invasive and non-invasive biospecimens. Existing biomarkers for lung cancer diagnosis as well as new biomarkers discovered specifically in this clinical setting will …

fiberoptic bronchoscopy
lung cancer
lung cancer screening
Boston University Medical Center
 (3.3 away) Contact site
  • 01 May, 2021
  • +14 other locations
Identification of Biomarkers for Patients With Vascular Anomalies

The study will use blood (serum and plasma) and tissue obtained from participants undergoing prescribed surgical resection of vascular anomalies of interest proposed in this study. The study will also use blood (serum and plasma) and tissue collected and stored in a tissue bank maintained by the Department of Hematology/Oncology.

Boston Children's Hospital
 (2.5 away) Contact site
  • 15 Feb, 2021
  • +1 other locations
Barrett's Esophagus Patient Registry

The ultimate goal of the Barrett's Esophagus Patient Registry is to help develop more effective targeted screening strategies and treatment options for Barrett's esophagus and esophageal adenocarcinoma (EAC). We plan to do by developing a registry that will serve as a platform. Examples of analyses could include identifying genetic determinants …

esophageal dysmotility
course of illness
esophageal adenocarcinoma
gastroesophageal reflux
Massachusetts General Hospital
 (4.5 away) Contact site
  • 07 Nov, 2020
  • 1 location