Brookline, Massachusetts Clinical Trials

A listing of Brookline, Massachusetts clinical trials actively recruiting patient volunteers.

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Found 2062 clinical trials
Analysis of Both Sex and Device Specific Factors on Outcomes in Patients With Non-Ischemic Cardiomyopathy

The purpose of this registry is to prospectively assess outcomes of device-treated ventricular tachyarrhythmias and all-cause mortality in non-ischemic cardiomyopathy patients indicated for ICD or CRT-D implantation for the primary prevention of sudden cardiac death. Differences in outcomes will be evaluated by sex and by device type.

ischemic cardiomyopathy
sudden cardiac death
Massachusetts General Hospital
 (4.5 away) Contact site
  • 21 Aug, 2021
  • +51 other locations
Observational Study Investigating Clinical & Anthropometric Characteristics of Children With Achondroplasia.

This is a registry study in children with achondroplasia, age 0-10 years, to be conducted at multiple clinical centers in several countries. Information collected will include in anthropometric characteristics, related symptoms, tests, & treatments Children's information will be collected in the registry for a maximum of 5 years.

Boston Children's Hospital
 (2.5 away) Contact site
  • 20 Jun, 2021
  • +51 other locations
A 5-year Longitudinal Observational Study of Patients Undergoing Therapy for IMISC

TARGET-DERM is a 5-year, longitudinal, observational study of adult and pediatric patients being managed for Atopic Dermatitis and other Immune-Mediated Inflammatory Skin Conditions (IMISC) in usual clinical practice. TARGET-DERM will create a research registry of patients with IMISC within academic and community real-world practices in order to assess the safety …

skin disease
skin disorder
Integrated Dermatology of Massachusetts
 (8.7 away) Contact site
  • 13 Aug, 2021
  • +49 other locations
Observational Study of Long Acting Injectable Medications (LAIs) in Schizophrenia (OASIS)

The objectives of this study are to describe characteristics, treatment patterns, and outcomes of patients with schizophrenia newly initiated on 1 of 4 FDA-approved atypical Long Acting Injectable (LAI) antipsychotics (ABILIFY MAINTENA, ARISTADA, INVEGA SUSTENNA or RISPERDAL CONSTA)

Alkermes Investigational Site
 (2.3 away) Contact site
  • 11 May, 2021
  • +50 other locations
Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort

Enroll-HD is a longitudinal, observational, multinational study that integrates two former Huntington's disease (HD) registries-REGISTRY in Europe, and COHORT in North America and Australasia-while also expanding to include sites in Latin America. More than 20,000 participants have now enrolled into the study. With annual assessments and no end date, Enroll-HD …

Beth Israel Deaconess Medical Center
 (2.3 away) Contact site
  • 20 May, 2021
  • +255 other locations
TRC-PAD Program: In-Clinic Trial-Ready Cohort

The purpose of the TRC-PAD study is to develop a large, well-characterized, biomarker-confirmed, trial-ready cohort to facilitate rapid enrollment into AD prevention trials utilizing the APT Webstudy and subsequent referral to in-clinic evaluation and biomarker confirmation. Participants with known biomarker status may have direct referral to the Trial-Ready Cohort. If …

neuropsychological test
positron emission tomography
Brigham & Women's Hospital
 (4.5 away) Contact site
  • 04 Sep, 2021
  • +51 other locations
Evaluation of Patient Outcomes From the Kidney Allograft Outcomes AlloSure Registry

This is an observational study to evaluate safety and efficacy outcomes in renal transplant recipients in whom post-transplant care is managed using AlloSure. AlloSure is a non-invasive test to measure donor-derived cell-free DNA (dd-cfDNA). The AlloSure test is intended to assess the probability of allograft rejection in kidney transplant recipients …

gene expression
kidney biopsy
kidney transplant
Beth Israel Deaconess Medical Center
 (2.3 away) Contact site
  • 03 Sep, 2021
  • +72 other locations
Precision-Based Genomics in Prostate Cancer

Background Prostate cancer is the most common cancer and the second leading cause of death in males in the United States. Researchers want to find additional gene mutations that may increase a man s risk for prostate cancer and may affect how aggressive the disease is. Objective To look at …

Dana Farber Cancer Institute
 (2.3 away) Contact site
  • 24 Sep, 2021
  • +11 other locations
Personalized CRT - PSR

The purpose of this study is to evaluate the cardiac resynchronization therapy (CRT) response in a real-world patient population and evaluate options to address non-response and patient management.

cardiac resynchronization therapy
 (4.5 away) Contact site
  • 26 Jan, 2021
  • +119 other locations
Apple Heart & Movement Study

This study will look for factors that affect heart health and potentially cause deterioration in mobility or heart function. Participant's Apple Watch and iPhone can help researchers gain a better understanding of potential early warning signs. This can lead to new interventions and products that will help millions lead longer, …

Brigham and Women's Hospital
 (2.5 away) Contact site
  • 02 Aug, 2021
  • 1 location