Brookline, Massachusetts Clinical Trials

A listing of Brookline, Massachusetts clinical trials actively recruiting patient volunteers.

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Found 2059 clinical trials
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Study of Oral Navitoclax Tablet In Combination With Oral Ruxolitinib Tablet When Compared With Oral Ruxolitinib Tablet To Assess Change In Spleen Volume In Adult Participants With Myelofibrosis

www.MyelofibrosisResearch.com Myelofibrosis is a type of bone marrow cancer that usually develops slowly and disrupts body's normal production of blood cells. It causes bone marrow scarring, leading to severe anemia that can cause weakness and fatigue. It can also cause a low number of blood-clotting cells called platelets, which increases …

Beth Israel Deaconess Medical Center /ID# 224261
 (2.3 away) Contact site
  • 83 views
  • 29 Apr, 2021
  • +148 other locations
featured
The RADIANCE II Pivotal Study: A Study of the ReCor Medical Paradise System in Stage II Hypertension

The objective of the RADIANCE II Pivotal study is to demonstrate the effectiveness and safety of the Paradise System in subjects with Stage 2 hypertension on 0-2 medications at the time of consent. Prior to randomization, subjects will be hypertensive in the absence of hypertension medication.

angiography
hypertensive medication
renal angiogram
antihypertensive therapy
hypertension
The Brigham and Women's Hospital
 (1.8 away) Contact site
  • 897 views
  • 10 Sep, 2021
  • +82 other locations
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INCB001158 Combined With Subcutaneous (SC) Daratumumab, Compared to Daratumumab SC, in Relapsed or Refractory Multiple Myeloma

The purpose of this study is to evaluate the safety and antitumor activity of INCB001158 in combination with daratumumab SC, compared with daratumumab SC alone, in participants with relapsed or refractory multiple myeloma who have received at least 3 but not more than 5 prior lines of multiple myeloma therapy. …

daratumumab
refractory multiple myeloma
Dana Farber Cancer Institute
 (2.3 away) Contact site
  • 73 views
  • 28 May, 2020
  • +27 other locations
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C3671008 Matisse

This randomized, double-blinded, placebo-controlled Phase 3 study is designed to evaluate the efficacy and safety of maternal immunization with RSVpreF against medically attended lower respiratory tract illness (MA-LRTI) in infants.

Boston Medical Center
 (3.3 away) Contact site
  • 140 views
  • 16 Sep, 2021
  • +159 other locations
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A Study to Evaluate the Efficacy and Safety of Pemigatinib Versus Chemotherapy in Unresectable or Metastatic Cholangiocarcinoma - (FIGHT-302)

The purpose of this study is to evaluate the efficacy and safety of pemigatinib versus gemcitabine plus cisplatin chemotherapy in first-line treatment of participants with unresectable or metastatic cholangiocarcinoma with FGFR2 rearrangement.  

primary cancer
cancer
FGFR2
metastatic cancer
Beth Israel Deaconess Medical Center
 (2.3 away) Contact site
  • 173 views
  • 25 Aug, 2021
  • +145 other locations
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ECOSPOR IV: An Open-Label Extension of Study SERES-012 and Open-Label Program for Evaluating SER-109 in Adult Subjects with Recurrent Clostridioides difficile Infection (RCDI)

ECOSPOR IV is a Phase 3, multicenter, Open Label study to evaluate the safety and tolerability of SER-109 in adult subjects with recurrent CDI.

clostridium difficile
Beth Israel Deaconess Medical Center
 (2.2 away) Contact site
  • 41 views
  • 21 Dec, 2020
  • +76 other locations
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[ONLINE] SPEECH BIOMARKERS: NEUROCOGNITIVE FUNCTIONING IN HEALTHY ADULTS

The Frontotemporal Degeneration Center and the Linguistic Data Consortium at the University of Pennsylvania are working to develop simple, easy, and effective ways to track neurocognitive health through short interactions with a web app. You can help us create a large open dataset, which researchers all over the world will …

Online253
 (3.1 away) Contact site
  • 792 views
  • 22 Oct, 2020
  • +251 other locations
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[Remote] Beyond Listening: A music-based intervention

1.This study is for people with dementia and their family caregiver. 2. The intervention is a 6-week psychoeducational, music-based workshop designed for caregivers of PWD. The caregiver will attend a one-hour, online session for 6 consecutive weeks. Caregivers will implement a daily caregiving routine that incorporates singing, music with movement and …

[Remote] Beyond Listening: A music-based intervention
 (3.1 away) Contact site
  • 32 views
  • 16 Jun, 2021
  • +241 other locations
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The RADIANCE II Pivotal Study: A Study of the ReCor Medical Paradise System in Stage II Hypertension

RADIANCE-II is a pivotal trial, currently enrolling patients, to study the safety and effectiveness of the Paradise System to reduce blood pressure in patients with hypertension, in the absence of antihypertensive medications. RADIANCE-II is currently enrolling patients with uncontrolled blood pressure on 0-2 medications.  

The Brigham and Women's Hospital
 (4.5 away) Contact site
  • 317 views
  • 30 Mar, 2021
  • +20 other locations
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Have you been a part of or witnessed a traumatic event?

Has this traumatic event that has caused lingering effects like anxiety, insomnia or nightmares? Boston Clinical Trials is conducting a new study for post traumatic stress disorder (PTSD.)

Boston Clinical Trials
 (3.0 away) Contact site
  • 541 views
  • 23 Nov, 2020
  • 1 location