Brookline, Massachusetts Clinical Trials

A listing of Brookline, Massachusetts clinical trials actively recruiting patient volunteers.

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Found 1836 clinical trials
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A Study Evaluating Tolerability and Efficacy of Navitoclax Alone or in Combination With Ruxolitinib in Participants With Myelofibrosis

www.MyelofibrosisResearch.com This is a Phase 2 open-label, multicenter study evaluating tolerability and efficacy of navitoclax alone or when added to ruxolitinib in participants with myelofibrosis.

Dana-Farber Cancer Institute /ID# 162675
 (2.3 away) Contact site
  • 251 views
  • 29 Apr, 2021
  • +134 other locations
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Study of Oral Navitoclax Tablet In Combination With Oral Ruxolitinib Tablet When Compared With Oral Ruxolitinib Tablet To Assess Change In Spleen Volume In Adult Participants With Myelofibrosis

www.MyelofibrosisResearch.com Myelofibrosis is a type of bone marrow cancer that usually develops slowly and disrupts body's normal production of blood cells. It causes bone marrow scarring, leading to severe anemia that can cause weakness and fatigue. It can also cause a low number of blood-clotting cells called platelets, which increases …

Beth Israel Deaconess Medical Center /ID# 224261
 (2.3 away) Contact site
  • 32 views
  • 29 Apr, 2021
  • +148 other locations
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The RADIANCE II Pivotal Study: A Study of the ReCor Medical Paradise System in Stage II Hypertension

The objective of the RADIANCE II Pivotal study is to demonstrate the effectiveness and safety of the Paradise System in subjects with Stage 2 hypertension on 0-2 medications at the time of consent. Prior to randomization, subjects will be hypertensive in the absence of hypertension medication.

antihypertensive drugs
angiography
antihypertensive therapy
hypertension
hypertensive medication
The Brigham and Women's Hospital
 (1.8 away) Contact site
  • 877 views
  • 13 Jun, 2021
  • +82 other locations
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A Study to Evaluate the Efficacy and Safety of Pemigatinib Versus Chemotherapy in Unresectable or Metastatic Cholangiocarcinoma - (FIGHT-302)

The purpose of this study is to evaluate the efficacy and safety of pemigatinib versus gemcitabine plus cisplatin chemotherapy in first-line treatment of participants with unresectable or metastatic cholangiocarcinoma with FGFR2 rearrangement.  

cancer
metastatic cancer
primary cancer
FGFR2
Beth Israel Deaconess Medical Center
 (2.3 away) Contact site
  • 154 views
  • 14 Dec, 2020
  • +154 other locations
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INCB001158 Combined With Subcutaneous (SC) Daratumumab, Compared to Daratumumab SC, in Relapsed or Refractory Multiple Myeloma

The purpose of this study is to evaluate the safety and antitumor activity of INCB001158 in combination with daratumumab SC, compared with daratumumab SC alone, in participants with relapsed or refractory multiple myeloma who have received at least 3 but not more than 5 prior lines of multiple myeloma therapy. …

daratumumab
refractory multiple myeloma
Dana Farber Cancer Institute
 (2.3 away) Contact site
  • 71 views
  • 28 May, 2020
  • +27 other locations
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ECOSPOR III: A Phase 3 Multicenter, RandomizeEd, Double Blind, Placebo COntrolled, Parallel Group Study to Evaluate the Safety, Tolerability, & Efficacy of SER-109 vs. Placebo to Reduce Recurrence of ClOstRidium Difficile Infection (CDI) in Adults

ECOSPOR III is a Phase 3, multicenter, randomized, double-blind, placebo-controlled, parallel-group study of the safety, tolerability, and efficacy of SER-109 versus placebo in adult subjects 18 years of age or older with recurrent CDI, defined as: a history of ≥ 3 CDI episodes within 9 months, inclusive of the current …

vancomycin
clostridium difficile
antibiotic therapy
fidaxomicin
antibiotics
Massachusetts General Hospital
 (4.5 away) Contact site
  • 1092 views
  • 21 Dec, 2020
  • +71 other locations
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ECOSPOR IV: An Open-Label Extension of Study SERES-012 and Open-Label Program for Evaluating SER-109 in Adult Subjects with Recurrent Clostridioides difficile Infection (RCDI)

ECOSPOR IV is a Phase 3, multicenter, Open Label study to evaluate the safety and tolerability of SER-109 in adult subjects with recurrent CDI.

clostridium difficile
Beth Israel Deaconess Medical Center
 (2.2 away) Contact site
  • 37 views
  • 21 Dec, 2020
  • +76 other locations
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The RADIANCE II Pivotal Study: A Study of the ReCor Medical Paradise System in Stage II Hypertension

RADIANCE-II is a pivotal trial, currently enrolling patients, to study the safety and effectiveness of the Paradise System to reduce blood pressure in patients with hypertension, in the absence of antihypertensive medications. RADIANCE-II is currently enrolling patients with uncontrolled blood pressure on 0-2 medications.  

The Brigham and Women's Hospital
 (4.5 away) Contact site
  • 315 views
  • 30 Mar, 2021
  • +20 other locations
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Have you been a part of or witnessed a traumatic event?

Has this traumatic event that has caused lingering effects like anxiety, insomnia or nightmares? Boston Clinical Trials is conducting a new study for post traumatic stress disorder (PTSD.)

Boston Clinical Trials
 (3.0 away) Contact site
  • 526 views
  • 23 Nov, 2020
  • 1 location
featured
Do you often feel sad, down and unmotivated? Have you been taking medication for depression but still have symptoms?

Do you often feel sad, down and unmotivated? Have you been taking medication for depression but still have symptoms?

Boston Clinical Trials
 (3.0 away) Contact site
  • 2056 views
  • 07 Nov, 2020
  • 1 location