Metairie, Louisiana Clinical Trials

A listing of Metairie, Louisiana clinical trials actively recruiting patient volunteers.

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Found 29 clinical trials
A Dose Escalation Study to Evaluate Safety Reactogenicity and Immunogenicity of mRNA-1345 in Healthy Adults and in Children Who Are Respiratory Syncytial Virus (RSV)-Seropositive

The primary objectives of this study are to evaluate the tolerability and reactogenicity of a single injection of 1 of up to 5 dose levels of mRNA-1345 in younger adults, women of child-bearing potential, and older adults; of 3 injections of the middle dose level of mRNA-1345 given 56 days …

body mass index
 (3.1 away) Contact site
  • 04 Jul, 2021
  • +20 other locations
Study of AMG 509 in Subjects With Metastatic Castration-Resistant Prostate Cancer

Evaluate the safety and tolerability of AMG 509 in adult subjects and determine the maximum tolerated dose (MTD) or recommended phase 2 dose (RP2D).

metastatic castration-resistant prostate cancer
progressive disease
neutrophil count
castration-resistant prostate cancer
Research Site
 (4.9 away) Contact site
  • 08 Sep, 2021
  • +33 other locations
A Study of RGX-104 in Patients With Advanced Solid Malignancies and Lymphoma

Study RGX-104-001 is a Phase 1, first-in-human, dose escalation and expansion study of RGX-104, an oral small molecule targeting the liver X receptor (LXR), as a single agent and in combination with nivolumab, ipilimumab, docetaxel, or pembrolizumab plus carboplatin/pemetrexed. RGX-104 activates LXR, resulting in depletion of both myeloid-derived suppressor cells …

neutrophil count
lung cancer
treatment regimen
Ochsner Clinic Foundation
 (1.6 away) Contact site
  • 12 Feb, 2021
  • +23 other locations
A Study of PRT543 in Participants With Advanced Solid Tumors and Hematologic Malignancies

This is a Phase 1 cohort, dose-escalation, dose-expansion study of PRT543 in patients with advanced cancers who have exhausted available treatment options. The purpose of this study is to define a safe dose and schedule to be used in subsequent development of PRT543.

Ochsner Clinic Foundation
 (1.6 away) Contact site
  • 07 Aug, 2021
  • +22 other locations
Study Evaluating GZ17-6.02 in Patients With Advanced Solid Tumors or Lymphoma

This study will evaluate the safety, pharmacokinetics, and pharmacodynamic effects of a novel anti-cancer drug, GZ17-6.02 administered to patients with advanced solid tumors or lymphoma, which have progressed after receiving standard/approved therapy or where there is no approved therapy.

cancer drug
chemotherapy regimen
kidney function tests
Ochsner Clinic Foundation
 (1.6 away) Contact site
  • 08 May, 2021
  • +2 other locations
A Study of an Intratumoral Oncolytic Virus in Patients With Advanced Metastatic Solid Tumors

The purpose of this study is to assess the safety and tolerability of ASP9801 and to determine the recommended phase 2 dose (RP2D). The study will also evaluate antitumor activity, objective response rate, pharmacokinetics and virus shedding of ASP9801.

solid neoplasm
solid tumor
measurable disease
Ochsner Clinic Foundation
 (1.6 away) Contact site
  • 17 Sep, 2021
  • +19 other locations
A Study of SHP655 (rADAMTS13) in Sickle Cell Disease

SHP655 is a medicine used to treat sickle cell disease (SCD). The main aim of the study is to measure the safety and tolerability of SHP655 in SCD participants. Study participants will receive SHP655 or placebo on Day 1. Their SCD will be treated by their doctor according to their …

vaso-occlusive crisis
Ochsner Health System
 (1.6 away) Contact site
  • 30 Aug, 2021
  • +14 other locations
Assessment of KAN-101 in Celiac Disease (ACeD)

A safety study of KAN-101 in patients with celiac disease. The study has two parts: Part A - first in human study in which patients receive a single dose of KAN-101 Part B - patients will receive three doses of either KAN-101 or placebo

serologic test
villous atrophy
Tandem Clinical Research
 (8.9 away) Contact site
  • 08 Aug, 2021
  • +12 other locations
Trial of Intravesical Measles Virotherapy in Patients With Bladder Cancer Who Are Undergoing Radical Cystectomy

This is a Phase 1 study designed to test the tolerability and feasibility of intravesical therapy with an attenuated Measles virus (MV-NIS) in patients with urothelial carcinoma who are undergoing radical cystectomy but are ineligible or do not desire neoadjuvant chemotherapy.

bladder cancer
radical cystectomy
Ochsner Health
 (1.8 away) Contact site
  • 27 Jun, 2021
  • +2 other locations
Pembrolizumab in Treating Patients With HIV and Relapsed Refractory or Disseminated Malignant Neoplasms

This phase I trial studies the side effects of pembrolizumab in treating patients with human immunodeficiency virus (HIV) and malignant neoplasms that have come back (relapsed), do not respond to treatment (refractory), or have distributed over a large area in the body (disseminated). Immunotherapy with monoclonal antibodies, such as pembrolizumab, …

lung cancer
antibody therapy
solid tumors
direct bilirubin
Louisiana State University Health Science Center
 (4.9 away) Contact site
  • 16 Aug, 2021
  • +4 other locations