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Houston, Louisiana Clinical Trials

A listing of Houston, Louisiana clinical trials actively recruiting patient volunteers.

RESULTS

Found (20) clinical trials

Study of Olaparib Maintenance Following Cabazitaxel-Carbo in Men With AVPC

Study Groups: If you are found to be eligible to take part in this study, you will be randomly assigned (as in a roll of dice) to 1 of 2 study groups. This is done because no one knows if one study group is better, the same, or worse than ...

Phase

4.11 miles

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H-22411: BOTOX for Peyronie's Disease

Treatments for this disease have been limited and often unsuccessful. The goal of treatment is to reduce pain and maintain sexual function. Oral medicines that prevent plaque formation and promote plaque breakdown have not been effective. Many patients with the disease will require injections of medicines directly into the plaque. ...

Phase

4.11 miles

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A Randomized Phase 2 Trial of Combining Sipuleucel-T With Immediate vs. Delayed CTLA-4 Blockade for Prostate Cancer

This is an open-label randomized multicenter Phase 2 clinical trial combining SipT with ipilimumab in patients with chemotherapy-nave metastatic castration resistant prostate cancer (CRPC). All patients will be treated with standard SipT (Q2wks x 3). Patients will be randomized to one of two arms: Arm 1 (Immediate Treatment): Ipilimumab Q3wks ...

Phase

4.11 miles

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Study to Evaluate the Testicular Safety of Filgotinib in Adult Males With Moderately to Severely Active Ulcerative Colitis

The primary objective of this study is to evaluate the testicular safety of filgotinib in adult males with moderately to severely active ulcerative colitis.

Phase

4.11 miles

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A Study of Rucaparib in Patients With Metastatic Castration-resistant Prostate Cancer and Homologous Recombination Gene Deficiency

The purpose of this study is to determine how patients with metastatic castration-resistant prostate cancer, and evidence of a homologous recombination gene deficiency, respond to treatment with rucaparib.

Phase

4.11 miles

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A Study for Subjects With Prostate Cancer Who Previously Participated in an Enzalutamide Clinical Study

Subjects should continue on the treatment regimen that the subject was receiving in the prior study. Dose changes of any of the prior therapies subjects were receiving on the previous protocol are allowed after medical monitor approval. The day 1 visit for this study should coincide with the last treatment ...

Phase

4.11 miles

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A Dynamic Allocation Modular Sequential Trial of Approved and Promising Therapies in Men With Metastatic Castrate Resistant Prostate Cancer (DynaMO)

Study Groups: If you are found to be eligible to take part in this study, you will be assigned to Group 1 and receive apalutamide, abiraterone, and prednisone. After 8 weeks of receiving treatment in Group 1, you will then have blood (about 4 teaspoons) drawn for biomarker testing. The ...

Phase

4.11 miles

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Trial of Pembrolizumab for Advanced Penile Squamous Cell Carcinoma

This is a multicenter trial to evaluate Pembrolizumab for patients with advanced penile squamous cell carcinoma following prior chemotherapy. Participating institutions are the University of Alabama at Birmingham (coordinating center), M.D. Anderson Cancer Center, University of Michigan, University of Minnesota, and Emory University. Patients will receive intravenous Pembrolizumab every 3 ...

Phase

4.11 miles

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Hypofractionated Proton Beam Therapy for Localized Prostate Cancer

PRIMARY OBJECTIVES: I. Estimate the incidence of grade 2 gastrointestinal toxicity following the proposed treatment regimens at 2 years post-treatment. SECONDARY OBJECTIVES: I. Estimate the change in health related quality of life (HRQOL) following the proposed treatment regimen compared to pre-treatment assessment as defined by Expanded Prostate Cancer Index Composite ...

Phase

4.11 miles

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Effectiveness of onaBoNT-A vs Oral Tamsulosin in Men With Benign Prostatic Hyperplasia and Lower Urinary Track Symptoms (BPH)

This proposed intervention is the first randomized clinical trial comparing the effects of onaBoNT-A prostate injection versus alpha adrenergic antagonist medication for LUTS associated with BPH. Up to this point, clinical studies using onaBoNT-A in the prostate has been limited to patient's refractory to -1 adrenoceptor blocker therapy. The study ...

Phase

4.11 miles

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