Louisville, Kentucky Clinical Trials

A listing of Louisville, Kentucky clinical trials actively recruiting patient volunteers.

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Found 80 clinical trials
LITES Task Order 0005 Prehospital Airway Control Trial (PACT)

The Prehospital Airway Control Trial (PACT) is a proposed 5 year, open label, multi-center, stepped-wedge randomized trial comparing airway management strategies of prehospital trauma patients. The initial airway attempt will be randomized to either usual care (control) or a supraglottic airway management approach (intervention). The primary outcome will be 24 …

University of Louisville
 (5.7 away) Contact site
  • 0 views
  • 15 Jun, 2021
  • +13 other locations
Plant Exosomes +/- Curcumin to Abrogate Symptoms of Inflammatory Bowel Disease

The trial will test the hypothesis that edible structures within plant cells (ginger) will have clinically important anti-inflammatory effects on the gut lining of patients with inflammable bowel disease. To evaluate the safety and tolerability of exosomes with and without curcumin in patients with Inflammatory Bowel Disease (IBD); To estimate …

University of Louisville
 (5.7 away) Contact site
  • 0 views
  • 16 May, 2021
  • 1 location
VNS Prospective Neuromodulation of Autonomic Immune and Gastrointestinal Systems

Vagal nerve stimulation is a neurosurgical procedure consisting of implantation of an impulse generator battery with leads placed into the vagus nerve in the neck. This procedure was FDA approved for epilepsy in the 1990s and is commonly performed as an outpatient surgery. The mechanism of efficacy is not well …

Norton Healthcare
 (5.7 away) Contact site
  • 0 views
  • 09 May, 2021
  • +1 other locations
INVEST Feasibility - Minimally Invasive Endoscopic Surgery With Apollo in Patients With Brain Hemorrhage

The primary objective of this multicenter single arm feasibility study is to provide an assessment of enrollment and follow up feasibility for this patient population being treated with the Apollo Minimally Invasive Surgical Treatment (MIES). Patients who do not qualify for the INVEST Feasibility Study will be referred to the …

University of Louisville
 (5.7 away) Contact site
  • 17 views
  • 27 May, 2021
  • +6 other locations
P-15L Bone Graft in Transforaminal Lumbar Interbody Fusion With Instrumentation

The aim of this trial is to evaluate if P-15L bone graft (investigational device) is not inferior in effectiveness and safety to local autologous bone (and allograft where necessary) as an extender (control device) when applied in instrumented transforaminal lumbar interbody fusion (TLIF) in subjects with degenerative disc disease (DDD). …

diabetes
bone graft
leg pain
disc disease
back pain
Norton Leatherman Spine Center
 (5.7 away) Contact site
  • 251 views
  • 16 Jun, 2021
  • +36 other locations
Auricular Acupuncture vs SOC in Migraine HA

Patients with migraine headache will be offered the opportunity to participate in this randomized study evaluating auricular acupuncture versus standard treatment for migraine headaches for patients in the pediatric emergency department (ED).

headache
metoclopramide
Norton Children's Hospital
 (5.7 away) Contact site
  • 62 views
  • 25 Jan, 2021
  • +1 other locations
Vitamin D Oral Replacement in Asthma

The overall objective of the study is to determine the pharmacokinetics of Vitamin D supplementation in children who have asthma and are overweight or obese.

d vitamin
body mass index
vitamins
cholecalciferol
vitamin d supplementation
West Virginia University
 (321.9 away) Contact site
  • 452 views
  • 25 Jan, 2021
  • +14 other locations
Fibromyalgia Integrative Training for Adolescents With Juvenile Fibromyalgia

This study evaluates whether Fibromyalgia Integrative Training program for Teens (FIT Teens), a combined cognitive behavioral therapy and neuromuscular exercise training program is more effective in reducing disability in adolescents with Juvenile Fibromyalgia compared to cognitive behavioral therapy (CBT) alone or a graded aerobic exercise (GAE) program alone. One third …

cognitive therapy
fibromyalgia
aerobic exercise
behavioral therapy
University of Louisville
 (5.7 away) Contact site
  • 577 views
  • 25 Feb, 2021
  • +7 other locations
Harnessing Neuroplasticity to Enhance Functional Recovery During Chronic Recovery From Upper Extremity Nerve Repair

This study adopts a strategy that has arisen from basic neuroscience research on facilitating adaptive brain plasticity and applies this to rehabilitation to improve functional recovery in peripheral nervous system injuries (including hand transplantation, hand replantation, and surgically repaired upper extremity nerve injuries). The technique involves combining behavioral training with …

Christine Kleinert Institute for Hand & Microsurgery
 (5.7 away) Contact site
  • 20 views
  • 26 Jan, 2021
  • +2 other locations
Electrical Nerve Block for Amputation Pain

The purpose of the clinical trial is to learn whether electrical nerve block via the Altius System is a safe and effective treatment for patients with post-amputation pain.

nerve block
University of Louisville
 (5.7 away) Contact site
  • 131 views
  • 22 Apr, 2021
  • +27 other locations