Zion, Illinois Clinical Trials

A listing of Zion, Illinois clinical trials actively recruiting patient volunteers.

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Found 117 clinical trials
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

body mass index
cardiovascular disease
hemoglobin a1c
Clinical Investigation Specialists Inc
 (6.9 away) Contact site
  • 597 views
  • 12 Sep, 2021
  • +895 other locations
Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

PREVENTABLE is a multi-center, randomized, parallel group, placebo-controlled superiority study. Participants will be randomized 1:1 to atorvastatin 40 mg or placebo. This large study conducted in community-dwelling older adults without cardiovascular disease (CVD) or dementia will demonstrate the benefit of statins for reducing the primary composite of death, dementia, and …

mild cognitive impairment
hmg-coa reductase inhibitor
atorvastatin
dementia
primary prevention
North Chicago VA Medical Center
 (8.1 away) Contact site
  • 104 views
  • 26 Jun, 2021
  • +86 other locations
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

This phase II trial studies nivolumab and ipilimumab in treating patients with rare tumors. Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. This trial enrolls participants for …

pheochromocytoma
cancer of the ovary
neuroendocrine tumor
lepidic predominant adenocarcinoma
thyroidectomy
Midwestern Regional Medical Center
 (0.0 away) Contact site
  • 6048 views
  • 16 Sep, 2021
  • +817 other locations
An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Ulcerative Colitis

The present study D5272C00001 (Legacy # 3151-201-008) seeks to evaluate the efficacy and safety of brazikumab versus placebo in patients with moderately to severely active UC and will include assessments of clinical responses as demonstrated by improvement of symptoms and of colonic mucosal appearance as observed on endoscopy.

Research Site
 (7.6 away) Contact site
  • 0 views
  • 29 Jan, 2021
  • +67 other locations
Etrasimod Versus Placebo for the Treatment of Moderately Active Ulcerative Colitis

The purpose of this study is to determine whether oral etrasimod is a safe and effective treatment for moderately active ulcerative colitis in adult participants.

endoscopy
Illinois Gastroenterology Group
 (6.9 away) Contact site
  • 0 views
  • 09 Sep, 2021
  • +94 other locations
Filgotinib in the Induction and Maintenance of Remission in Adults With Moderately to Severely Active Crohn's Disease

The primary objectives of this study are to evaluate the safety and efficacy of filgotinib during induction and maintenance treatment of moderately to severely active Crohn's disease (CD) in participants who are biologic-naive and biologic-experienced. Participants who complete the study, or do not meet protocol response or remission criteria at …

vedolizumab
immunomodulators
corticosteroids
remission
tumor necrosis factor
Illinois Gastroenterology Group
 (6.9 away) Contact site
  • 12 views
  • 04 Jul, 2021
  • +551 other locations
A Study of Tirzepatide (LY3298176) in Participants With Obesity or Overweight for the Maintenance of Weight Loss

This is a study of tirzepatide in participants with obesity or overweight. The main purpose is to learn more about how tirzepatide maintains body weight loss. The study has two phases: a lead-in phase in which all participants take tirzepatide and a treatment phase in which participants will either continue …

hypertension
body mass index
cardiovascular disease
dyslipidemia
Clinical Investigation Specialists
 (6.9 away) Contact site
  • 98 views
  • 12 Sep, 2021
  • +78 other locations
A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes Who Have Obesity or Are Overweight

This is a study of tirzepatide in participants with type 2 diabetes who have obesity or are overweight. The main purpose is to learn more about how tirzepatide affects body weight. The study will last 79 weeks (22 visits).

glucagon
diabetes
hemoglobin a1c
glucagon-like peptide-1
Clinical Investigation Specialists
 (7.9 away) Contact site
  • 31 views
  • 12 Sep, 2021
  • +91 other locations
A Study of Abemaciclib (LY2835219) Plus Hormone Therapy in Participants With Early Breast Cancer

The main purpose of this study is to measure how well abemaciclib works in participants with early breast cancer who are taking hormone therapy after surgery. Participants must have breast cancer that is hormone receptor positive (HR+) and human epidermal receptor 2 positive (HER2+). Your participation could last up to …

trastuzumab
pertuzumab
invasive breast cancer
hormone therapy
erbb2
Cancer Treatment Centers of America
 (0.0 away) Contact site
  • 0 views
  • 12 Sep, 2021
  • +566 other locations
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer ALCHEMIST Chemo-IO Study

This phase III ALCHEMIST trial compares the addition of pembrolizumab to usual chemotherapy versus usual chemotherapy for the treatment of stage IB, II, or IIIA non-small cell lung cancer that has been removed by surgery. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the …

carcinoma
pemetrexed
gemcitabine
pembrolizumab
carboplatin
Aurora Cancer Care-Kenosha South
 (8.9 away) Contact site
  • 136 views
  • 15 Sep, 2021
  • +812 other locations