Zion, Illinois Clinical Trials

A listing of Zion, Illinois clinical trials actively recruiting patient volunteers.

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Found 117 clinical trials
A Study to Evaluate Dostarlimab Plus Carboplatin-paclitaxel Versus Placebo Plus Carboplatin-paclitaxel in Participants With Recurrent or Primary Advanced Endometrial Cancer

This is a 2 part study. Part 1 is to evaluate the efficacy and safety of dostarlimab plus carboplatin-paclitaxel followed by dostarlimab versus placebo plus carboplatin-paclitaxel followed by placebo; and Part 2 is to evaluate the efficacy and safety of dostarlimab plus carboplatin-paclitaxel followed by dostarlimab plus niraparib versus placebo …

neutrophil count
anticoagulant
direct bilirubin
carcinoma
carboplatin/paclitaxel
GSK Investigational Site
 (0.3 away) Contact site
  • 78 views
  • 05 Aug, 2021
  • +154 other locations
Maintenance Chemotherapy With or Without Local Consolidative Therapy in Treating Patients With Stage IV Non-small Cell Lung Cancer

This randomized phase II/III trial studies how well giving maintenance chemotherapy with or without local consolidation therapy works in treating patients with stage IV non-small cell lung cancer. Drugs used in maintenance chemotherapy, such as docetaxel, pemetrexed disodium, erlotinib hydrochloride, and gemcitabine work in different ways to stop the growth …

neutrophil count
systemic therapy
lung cancer
tumor cells
systemic chemotherapy
Aurora Cancer Care-Kenosha South
 (7.9 away) Contact site
  • 238 views
  • 26 Sep, 2021
  • +199 other locations
A Study to Evaluate the Effect of Testosterone Replacement Therapy (TRT) on the Incidence of Major Adverse Cardiovascular Events (MACE) and Efficacy Measures in Hypogonadal Men

This is a blinded and placebo-controlled study of topical testosterone replacement therapy (TRT) in symptomatic hypogonadal men with increased risk for cardiovascular (CV) disease.

replacement therapy
serum testosterone
testosterone
testosterone topical
testosterone level
Clinical Investigation Specialists, Inc. /ID# 170631
 (7.6 away) Contact site
  • 16902 views
  • 26 Sep, 2021
  • +495 other locations
Testing the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung Cancer

This phase III trial studies whether pembrolizumab alone as a first-line treatment, followed by pemetrexed and carboplatin with or without pembrolizumab after disease progression is superior to induction with pembrolizumab, pemetrexed and carboplatin followed by pembrolizumab and pemetrexed maintenance in treating patients with stage IV non-squamous non-small cell lung cancer. …

chronic hepatitis b
immunodeficiency
lung cancer
hcv viral load
systemic chemotherapy
Aurora Cancer Care-Kenosha South
 (8.9 away) Contact site
  • 213 views
  • 26 Sep, 2021
  • +832 other locations
Study of Pembrolizumab (MK-3475) Versus Placebo in Combination With Neoadjuvant Chemotherapy & Adjuvant Endocrine Therapy in the Treatment of Early-Stage Estrogen Receptor-Positive Human Epidermal Growth Factor Receptor 2-Negative (ER+/HER2-) Breast Cancer (MK-3475-756/KEYNOTE-756)

The purpose of this study is to assess the efficacy and safety of pembrolizumab (MK-3475) versus placebo in combination with neoadjuvant (pre-surgery) chemotherapy and adjuvant (post-surgery) endocrine therapy in the treatment of adults who have high-risk early-stage estrogen receptor-positive, human epidermal growth factor receptor 2-negative (ER+/HER2-) breast cancer. The primary …

EGFR
progesterone receptor
inflammatory breast cancer
cancer treatment
core needle biopsy
Midwestern Regional Medical Center, Inc. ( Site 0077)
 (0.0 away) Contact site
  • 188 views
  • 26 Sep, 2021
  • +287 other locations
Multiparametric MRI in Evaluating Cancer Stage and Helping Treatment Planning in Patients With Prostate Cancer

This phase II trial studies how well multiparametric magnetic resonance imaging (MRI) works in evaluating cancer stage and helping treatment planning in patients with prostate cancer. Multiparametric MRI may be useful for evaluating the type of cancer in finding aggressive disease.

multiparametric magnetic resonance imaging
Midwestern Regional Medical Center
 (0.3 away) Contact site
  • 113 views
  • 24 Jan, 2021
  • +14 other locations
Semaglutide Effects on Heart Disease and Stroke in Patients With Overweight or Obesity

The researchers are doing the study to see if semaglutide may reduce the risk of having cardiovascular events in patients with overweight or obesity and with prior cardiovascular disease. The participant will either get semaglutide (active medicine) or placebo ("dummy" medicine). Which treatment the participants get is decided by chance. …

cardiovascular disease
body mass index
overweight or obesity
Novo Nordisk Investigational Site
 (7.9 away) Contact site
  • 7790 views
  • 25 Sep, 2021
  • +1166 other locations
An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Crohn's Disease

This study seeks to evaluate the safety and efficacy of brazikumab versus placebo (Stage I) and versus an active comparator (Stage 2) in participants with moderately to severely active CD and will include assessments of clinical response as demonstrated by improvement of symptoms and colonic mucosal appearance as observed on …

antibiotics
immunomodulators
mercaptopurine
conventional treatment
azathioprine
Illinois Gastroenterology Group, LLC
 (7.6 away) Contact site
  • 418 views
  • 20 Sep, 2021
  • +320 other locations
A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes

The researchers are doing this study to look whether the type 2 diabetes medicine, semaglutide, has a positive effect on heart disease. Participants will either get semaglutide tablets or placebo tablets ("dummy" medicine) - which treatment is decided by chance. Participants must take one tablet with water every morning on …

stroke
semaglutide
chronic disease
Novo Nordisk Investigational Site
 (7.6 away) Contact site
  • 1280 views
  • 12 Aug, 2021
  • +557 other locations
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

This screening and multi-sub-study randomized phase II/III trial will establish a method for genomic screening of similar large cancer populations followed by assigning and accruing simultaneously to a multi-sub-study hybrid Master Protocol (Lung-MAP). The type of cancer trait (biomarker) will determine to which sub-study, within this protocol, a participant will …

Midwestern Regional Medical Center
 (0.0 away) Contact site
  • 193 views
  • 10 May, 2021
  • +876 other locations