Zion, Illinois Clinical Trials

A listing of Zion, Illinois clinical trials actively recruiting patient volunteers.

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Found 117 clinical trials
Testing the Addition of Ruxolitinib to the Usual Treatment (Tyrosine Kinase Inhibitors) for Chronic Myeloid Leukemia

This randomized phase II trial studies how well ruxolitinib phosphate, and bosutnib, dasatinib, or nilotinib, work in treating patients with chronic myeloid leukemia. Chronic myeloid leukemia cells produce a protein called BCR-ABL. The BCR-ABL protein helps chronic myeloid leukemia cells to grow and divide. Tyrosine kinase inhibitors, such as bosutinib, …

Aurora Cancer Care-Kenosha South
 (7.9 away) Contact site
  • 38 views
  • 11 May, 2021
  • +441 other locations
An Extension Study for Treatment of Moderately to Severely Active Ulcerative Colitis

The purpose of this open-label extension (OLE) study is to evaluate the safety and efficacy of etrasimod in participants with moderately to severely active ulcerative colitis (UC) who previously received double-blinded treatment (either etrasimod 2 mg per day or placebo) during participation in one of two Phase 3 double-blinded, placebo-controlled …

Illinois Gastroenterology Group
 (6.9 away) Contact site
  • 133 views
  • 05 Aug, 2021
  • +391 other locations
Derazantinib and Atezolizumab in Patients With Urothelial Cancer

The purpose of this study is to evaluate efficacy of derazantinib monotherapy or derazantinib-atezolizumab in combination in patients with advanced urothelial cancer harboring fibroblast growth factor receptor (FGFR) genetic aberrations (GA) of various clinical stages of disease progression and prior treatments.

cancer
FGFR3
growth factor
renal function
advanced urothelial carcinoma
Midwestern Regional Medical Center, Inc. DBA CTCA, Chicago
 (0.3 away) Contact site
  • 9 views
  • 30 Jul, 2021
  • +112 other locations
A Study to Evaluate Dostarlimab Plus Carboplatin-paclitaxel Versus Placebo Plus Carboplatin-paclitaxel in Participants With Recurrent or Primary Advanced Endometrial Cancer

This is a 2 part study. Part 1 is to evaluate the efficacy and safety of dostarlimab plus carboplatin-paclitaxel followed by dostarlimab versus placebo plus carboplatin-paclitaxel followed by placebo; and Part 2 is to evaluate the efficacy and safety of dostarlimab plus carboplatin-paclitaxel followed by dostarlimab plus niraparib versus placebo …

cancer
serum pregnancy test
recurrent disease
carboplatin/paclitaxel
recurrent endometrial cancer
GSK Investigational Site
 (0.3 away) Contact site
  • 78 views
  • 05 Aug, 2021
  • +154 other locations
An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Ulcerative Colitis

The present study D5272C00001 (Legacy # 3151-201-008) seeks to evaluate the efficacy and safety of brazikumab versus placebo in patients with moderately to severely active UC and will include assessments of clinical responses as demonstrated by improvement of symptoms and of colonic mucosal appearance as observed on endoscopy.

Research Site
 (7.6 away) Contact site
  • 0 views
  • 29 Jan, 2021
  • +67 other locations
Etrasimod Versus Placebo for the Treatment of Moderately Active Ulcerative Colitis

The purpose of this study is to determine whether oral etrasimod is a safe and effective treatment for moderately active ulcerative colitis in adult participants.

endoscopy
Illinois Gastroenterology Group
 (6.9 away) Contact site
  • 0 views
  • 09 Sep, 2021
  • +94 other locations
Filgotinib in the Induction and Maintenance of Remission in Adults With Moderately to Severely Active Crohn's Disease

The primary objectives of this study are to evaluate the safety and efficacy of filgotinib during induction and maintenance treatment of moderately to severely active Crohn's disease (CD) in participants who are biologic-naive and biologic-experienced. Participants who complete the study, or do not meet protocol response or remission criteria at …

tumour necrosis
tumor necrosis factor
corticosteroids
immunomodulators
maintenance treatment
Illinois Gastroenterology Group
 (6.9 away) Contact site
  • 12 views
  • 04 Jul, 2021
  • +551 other locations
A Study of Tirzepatide (LY3298176) in Participants With Obesity or Overweight for the Maintenance of Weight Loss

This is a study of tirzepatide in participants with obesity or overweight. The main purpose is to learn more about how tirzepatide maintains body weight loss. The study has two phases: a lead-in phase in which all participants take tirzepatide and a treatment phase in which participants will either continue …

dyslipidemia
hypertension
body mass index
cardiovascular disease
Clinical Investigation Specialists
 (6.9 away) Contact site
  • 98 views
  • 12 Sep, 2021
  • +78 other locations
A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes Who Have Obesity or Are Overweight

This is a study of tirzepatide in participants with type 2 diabetes who have obesity or are overweight. The main purpose is to learn more about how tirzepatide affects body weight. The study will last 79 weeks (22 visits).

glucagon-like peptide-1
hemoglobin a1c
diabetes
glucagon
Clinical Investigation Specialists
 (7.9 away) Contact site
  • 31 views
  • 12 Sep, 2021
  • +91 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

hemoglobin a1c
body mass index
cardiovascular disease
Clinical Investigation Specialists Inc
 (6.9 away) Contact site
  • 597 views
  • 12 Sep, 2021
  • +895 other locations