Yorkville, Illinois Clinical Trials

A listing of Yorkville, Illinois clinical trials actively recruiting patient volunteers.

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Found 49 clinical trials
Vitamin D3 With Chemotherapy and Bevacizumab in Treating Patients With Advanced or Metastatic Colorectal Cancer

This phase III trial studies how well vitamin D3 given with standard chemotherapy and bevacizumab works in treating patients with colorectal cancer that has spread to other parts of the body. Vitamin D3 helps the body use calcium and phosphorus to make strong bones and teeth. Drugs used in chemotherapy, …

irinotecan
tumor cells
cancer treatment
rifampin
measurable disease
Edward Hospital/Cancer Center?Plainfield
 (11.6 away) Contact site
  • 65 views
  • 27 Jul, 2021
  • +978 other locations
T-DM1 and Tucatinib Compared With T-DM1 Alone in Preventing Relapses in People With High Risk HER2-Positive Breast Cancer the CompassHER2 RD Trial

This phase III trial studies how well trastuzumab emtansine (T-DM1) and tucatinib work in preventing breast cancer from coming back (relapsing) in patients with high risk, HER2 positive breast cancer. T-DM1 is a monoclonal antibody, called trastuzumab, linked to a chemotherapy drug, called DM1. Trastuzumab is a form of targeted …

Rush - Copley Medical Center
 (12.8 away) Contact site
  • 0 views
  • 26 Jul, 2021
  • +762 other locations
Hypofractionated Radiation Therapy After Mastectomy in Preventing Recurrence in Patients With Stage IIa-IIIa Breast Cancer

This randomized phase III trial studies how well hypofractionated radiation therapy works in preventing recurrence in patients with stage IIa-IIIa cancer who have undergone mastectomy. Hypofractionated radiation therapy delivers higher doses of radiation therapy over a shorter period of time and may kill more tumor cells that remain after surgery …

invasive breast cancer
diabetes
beta-human chorionic gonadotropin
tumor cells
carcinoma in situ
Rush-Copley Healthcare Center
 (0.2 away) Contact site
  • 335 views
  • 28 Jul, 2021
  • +911 other locations
A Phase II/III Trial of Nivolumab Ipilimumab and GM-CSF in Patients With Advanced Melanoma

This phase II/III trial studies the side effects of nivolumab and ipilimumab when given together with or without sargramostim and to see how well they work in treating patients with stage III-IV melanoma that cannot be removed by surgery (unresectable). Immunotherapy with monoclonal antibodies, such as ipilimumab and nivolumab, may …

colony-stimulating factors
diabetes
tumor cells
interferon
immunomodulators
Rush-Copley Healthcare Center
 (0.2 away) Contact site
  • 46 views
  • 01 Aug, 2021
  • +430 other locations
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

This phase II trial studies nivolumab and ipilimumab in treating patients with rare tumors. Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. This trial enrolls participants for …

cancer other
germ cell tumor of ovary
gastrointestinal stromal tumor
beta-human chorionic gonadotropin
tubal ligation
Rush - Copley Medical Center
 (12.8 away) Contact site
  • 6047 views
  • 01 Aug, 2021
  • +814 other locations
Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)

This ALCHEMIST trial studies genetic testing in screening patients with stage IB-IIIA non-small cell lung cancer that has been or will be removed by surgery. Studying the genes in a patient's tumor cells may help doctors select the best treatment for patients that have certain genetic changes.

tumor cells
paclitaxel
crizotinib
adenocarcinoma
metastasis
Edward Hospital/Cancer Center?Plainfield
 (11.6 away) Contact site
  • 1103 views
  • 01 Aug, 2021
  • +1138 other locations
Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors Lymphomas or Multiple Myeloma (The MATCH Screening Trial)

This phase II MATCH trial studies how well treatment that is directed by genetic testing works in patients with solid tumors or lymphomas that have progressed following at least one line of standard treatment or for which no agreed upon treatment approach exists. Genetic tests look at the unique genetic …

gnrh
dasatinib
tubal ligation
pertuzumab
biomarker analysis
Edward Hospital/Cancer Center?Plainfield
 (11.6 away) Contact site
  • 6087 views
  • 01 Aug, 2021
  • +1020 other locations
Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer The PDIGREE Study

This phase III trial compares the usual treatment (treatment with ipilimumab and nivolumab followed by nivolumab alone) to treatment with ipilimumab and nivolumab, followed by nivolumab with cabozantinib in patients with untreated renal cell carcinoma that has spread to other parts of the body. The addition of cabozantinib to the …

karnofsky performance status
tumor cells
calcium
measurable disease
pd-l1
Edward Hospital/Cancer Center?Plainfield
 (11.6 away) Contact site
  • 157 views
  • 01 Aug, 2021
  • +677 other locations
Testing the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung Cancer

This phase III trial studies whether pembrolizumab alone as a first-line treatment, followed by pemetrexed and carboplatin with or without pembrolizumab after disease progression is superior to induction with pembrolizumab, pemetrexed and carboplatin followed by pembrolizumab and pemetrexed maintenance in treating patients with stage IV non-squamous non-small cell lung cancer. …

aptt
international normalized ratio
tubal ligation
systemic chemotherapy
stage iv non-small cell lung cancer
Rush-Copley Healthcare Center
 (0.2 away) Contact site
  • 206 views
  • 01 Aug, 2021
  • +831 other locations
Testing the Addition of Ixazomib to Lenalidomide in Patients With Evidence of Residual Multiple Myeloma OPTIMUM Trial

This phase III trial studies how well lenalidomide in combination with ixazomib works compared to lenalidomide alone in treating patients with evidence of residual multiple myeloma after stem cell transplantation. Lenalidomide may help shrink or slow the growth of multiple myeloma. Ixazomib may stop the growth of cancer cells by …

bone marrow procedure
neutrophil count
cell transplantation
cancer
chemotherapy regimen
Rush - Copley Medical Center
 (12.8 away) Contact site
  • 0 views
  • 01 Aug, 2021
  • +84 other locations