Yorkville, Illinois Clinical Trials

A listing of Yorkville, Illinois clinical trials actively recruiting patient volunteers.

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Found 77 clinical trials
Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction

Heart failure with preserved ejection fraction (HFPEF) is common and deadly but without therapy. Inconclusive studies such as TOPCAT (Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist) suggest spironolactone may be effective in HFPEF, but it is generic and will not be studied by industry. SPIRRIT is …

aldosterone antagonists
nt-probnp
pro-brain natriuretic peptide
b-type natriuretic peptide
aldosterone
Fox Valley Clinical Research Center, LLC
 (9.5 away) Contact site
  • 46 views
  • 02 Jul, 2021
  • +147 other locations
Testing the Addition of Ruxolitinib to the Usual Treatment (Tyrosine Kinase Inhibitors) for Chronic Myeloid Leukemia

This randomized phase II trial studies how well ruxolitinib phosphate, and bosutnib, dasatinib, or nilotinib, work in treating patients with chronic myeloid leukemia. Chronic myeloid leukemia cells produce a protein called BCR-ABL. The BCR-ABL protein helps chronic myeloid leukemia cells to grow and divide. Tyrosine kinase inhibitors, such as bosutinib, …

Rush - Copley Medical Center
 (12.8 away) Contact site
  • 38 views
  • 11 May, 2021
  • +441 other locations
Vitamin D3 With Chemotherapy and Bevacizumab in Treating Patients With Advanced or Metastatic Colorectal Cancer

This phase III trial studies how well vitamin D3 given with standard chemotherapy and bevacizumab works in treating patients with colorectal cancer that has spread to other parts of the body. Vitamin D3 helps the body use calcium and phosphorus to make strong bones and teeth. Drugs used in chemotherapy, …

major surgery
rifampin
metastasis
adjuvant therapy
vitamin d
Edward Hospital/Cancer Center?Plainfield
 (11.6 away) Contact site
  • 65 views
  • 22 Jul, 2021
  • +978 other locations
Hypofractionated Radiation Therapy After Mastectomy in Preventing Recurrence in Patients With Stage IIa-IIIa Breast Cancer

This randomized phase III trial studies how well hypofractionated radiation therapy works in preventing recurrence in patients with stage IIa-IIIa cancer who have undergone mastectomy. Hypofractionated radiation therapy delivers higher doses of radiation therapy over a shorter period of time and may kill more tumor cells that remain after surgery …

human chorionic gonadotropin
skin carcinoma
lobular carcinoma in situ
tumor cells
ductal carcinoma in situ
Rush-Copley Healthcare Center
 (0.2 away) Contact site
  • 335 views
  • 21 Jul, 2021
  • +903 other locations
A Phase II/III Trial of Nivolumab Ipilimumab and GM-CSF in Patients With Advanced Melanoma

This phase II/III trial studies the side effects of nivolumab and ipilimumab when given together with or without sargramostim and to see how well they work in treating patients with stage III-IV melanoma that cannot be removed by surgery (unresectable). Immunotherapy with monoclonal antibodies, such as ipilimumab and nivolumab, may …

metastasis
metastatic melanoma
advanced melanoma
gm-csf
tumor cells
Rush-Copley Healthcare Center
 (0.2 away) Contact site
  • 46 views
  • 09 Jul, 2021
  • +429 other locations
Testing the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung Cancer

This phase III trial studies whether pembrolizumab alone as a first-line treatment, followed by pemetrexed and carboplatin with or without pembrolizumab after disease progression is superior to induction with pembrolizumab, pemetrexed and carboplatin followed by pembrolizumab and pemetrexed maintenance in treating patients with stage IV non-squamous non-small cell lung cancer. …

squamous non-small cell lung carcinoma
pd-l1
lung cancer
adjuvant therapy
metastasis
Rush-Copley Healthcare Center
 (0.2 away) Contact site
  • 206 views
  • 15 Jul, 2021
  • +830 other locations
Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer The PDIGREE Study

This phase III trial compares the usual treatment (treatment with ipilimumab and nivolumab followed by nivolumab alone) to treatment with ipilimumab and nivolumab, followed by nivolumab with cabozantinib in patients with untreated renal cell carcinoma that has spread to other parts of the body. The addition of cabozantinib to the …

karnofsky performance status
pd-l1
metastasis
metastatic renal cell carcinoma
cabozantinib
Edward Hospital/Cancer Center?Plainfield
 (11.6 away) Contact site
  • 157 views
  • 17 Jul, 2021
  • +675 other locations
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

This screening and multi-sub-study randomized phase II/III trial will establish a method for genomic screening of similar large cancer populations followed by assigning and accruing simultaneously to a multi-sub-study hybrid Master Protocol (Lung-MAP). The type of cancer trait (biomarker) will determine to which sub-study, within this protocol, a participant will …

Advocate Good Samaritan Hospital
 (24.8 away) Contact site
  • 193 views
  • 10 May, 2021
  • +876 other locations
Testing MK-3475 (Pembrolizumab) After Surgery for Localized Muscle-Invasive Bladder Cancer and Locally Advanced Urothelial Cancer

This phase III trial studies how well pembrolizumab works in treating patients with bladder cancer that has spread into the deep muscle of the bladder wall (muscle-invasive) or urothelial cancer that has spread from where it started to nearby tissue or lymph nodes (locally advanced). Monoclonal antibodies recognizing and blocking …

Rush - Copley Medical Center
 (12.8 away) Contact site
  • 836 views
  • 21 Jul, 2021
  • +755 other locations
S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer

This randomized research trial studies how well serum tumor marker directed disease monitoring works in monitoring patients with hormone receptor positive Her2 negative breast cancer that has spread to other places in the body. Using markers to prompt when scans should be ordered may be as good as the usual …

Rush - Copley Medical Center
 (12.8 away) Contact site
  • 139 views
  • 19 May, 2021
  • +481 other locations