Warrenville, Illinois Clinical Trials

A listing of Warrenville, Illinois clinical trials actively recruiting patient volunteers.

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Found 86 clinical trials
A Randomized Study of Olaparib or Placebo in Patients With Surgically Removed Pancreatic Cancer Who Have a BRCA1 BRCA2 or PALB2 Mutation The APOLLO Trial

This phase II trial investigates how well the addition of olaparib following completion of surgery and chemotherapy works in treating patients with pancreatic cancer that has been surgically removed (resected) and has a pathogenic mutation in BRCA1, BRCA2, or PALB2. Olaparib is an inhibitor of PARP, an enzyme that helps …

BRCA2
neutrophil count
adenocarcinoma
palb2
cancer chemotherapy
Rush - Copley Medical Center
 (5.9 away) Contact site
  • 0 views
  • 19 Sep, 2021
  • +217 other locations
Ovarian Suppression Evaluating Subcutaneous Leuprolide Acetate in Breast Cancer

This is a phase 3, single arm, open-label study evaluating the effectiveness of TOL2506 to suppress ovarian function in premenopausal women with HR+, HER2-negative breast cancer. The study will also aim to assess administration of TOL2506 in men with HR+ breast cancer. Study duration, for individual subjects, will be up …

estradiol
letrozole
erbb2
tamoxifen
anastrozole
Revive Research Institute, Inc.
 (251.5 away) Contact site
  • 0 views
  • 19 Sep, 2021
  • +5 other locations
Brentuximab Vedotin and Nivolumab With or Without Ipilimumab in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma

This phase I/II trial studies the side effects and best dose of ipilimumab and nivolumab when given together with brentuximab vedotin, and how well they work in treating patients with Hodgkin lymphoma that has returned after a period of improvement (recurrent) or has not responded to previous treatment (refractory). Immunotherapy …

Rush - Copley Medical Center
 (5.9 away) Contact site
  • 158 views
  • 19 Sep, 2021
  • +370 other locations
Testing the Addition of a New Anti-Cancer Drug Triapine to the Usual Chemotherapy Treatment (Cisplatin) During Radiation Therapy for Advanced-stage Cervical and Vaginal Cancers

This randomized phase III trial studies radiation therapy and cisplatin with triapine to see how well they work compared to the standard radiation therapy and cisplatin alone in treating patients with newly diagnosed stage IB2, II, or IIIB-IVA cervical cancer or stage II-IVA vaginal cancer. Radiation therapy uses high energy …

fludeoxyglucose
cervical carcinoma
neutrophil count
brachytherapy
antiretroviral
Northwestern Medicine Cancer Center Delnor
 (7.3 away) Contact site
  • 606 views
  • 19 Sep, 2021
  • +79 other locations
Pegylated Liposomal Doxorubicin Hydrochloride With Atezolizumab and/or Bevacizumab in Treating Patients With Recurrent Ovarian Fallopian Tube or Primary Peritoneal Cancer

This phase II/III trial studies how well pegylated liposomal doxorubicin hydrochloride with atezolizumab and/or bevacizumab work in treating patients with ovarian, fallopian tube, or primary peritoneal cancer that has come back (recurrent). Chemotherapy drugs, such as pegylated liposomal doxorubicin hydrochloride, work in different ways to stop the growth of tumor …

bevacizumab
pleural effusion
hormone therapy
neutrophil count
primary peritoneal carcinoma
Rush - Copley Medical Center
 (5.9 away) Contact site
  • 185 views
  • 19 Sep, 2021
  • +757 other locations
Testing the Addition of the Immunotherapy Drug Pembrolizumab to the Usual Radiation Treatment for Newly Diagnosed Early Stage High Intermediate Risk Endometrial Cancer

This phase III trial compares whether the addition of pembrolizumab to radiation therapy is more effective than radiation therapy alone in reducing the risk of cancer coming back (recurrence) in patients with newly diagnosed stage I-II endometrial cancer. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune …

Northwestern Medicine Cancer Center Warrenville
 (1.4 away) Contact site
  • 1 views
  • 19 Sep, 2021
  • +145 other locations
Testing the Addition of Pembrolizumab an Immunotherapy Cancer Drug to Olaparib Alone as Therapy for Patients With Pancreatic Cancer That Has Spread With Inherited BRCA Mutations

This phase II trial studies whether adding pembrolizumab to olaparib (standard of care) works better than olaparib alone in treating patients with pancreatic cancer with germline BRCA1 or BRCA2 mutations that has spread to other places in the body (metastatic). BRCA1 and BRCA2 are human genes that produce tumor suppressor …

Rush - Copley Medical Center
 (5.9 away) Contact site
  • 0 views
  • 19 Sep, 2021
  • +422 other locations
Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

This phase III trial compares the effect of bevacizumab and osimertinib combination vs. osimertinib alone for the treatment of non-small cell lung cancer that has spread outside of the lungs (stage IIIB-IV) and has a change (mutation) in a gene called EGFR. The EGFR protein is involved in cell signaling …

Rush - Copley Medical Center
 (5.9 away) Contact site
  • 0 views
  • 19 Sep, 2021
  • +382 other locations
A Study Testing the Effect of Immunotherapy (Ipilimumab and Nivolumab) in Patients With Recurrent Glioblastoma With Elevated Mutational Burden

This phase II trial studies the effect of immunotherapy drugs (ipilimumab and nivolumab) in treating patients with glioblastoma that has come back (recurrent) and carries a high number of mutations. Cancer is caused by changes (mutations) to genes that control the way cells function. Tumors with high number of mutations …

Rush - Copley Medical Center
 (5.9 away) Contact site
  • 0 views
  • 19 Sep, 2021
  • +311 other locations
Testing the Effects of Early Treatment With Venetoclax and Obinutuzumab Versus Delayed Treatment With Venetoclax and Obinutuzumab for Newly Diagnosed Patients With High-Risk Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Who Do Not Have Symptoms the EVOLVE CLL/SLL Study

This phase III trial compares early treatment with venetoclax and obinutuzumab versus delayed treatment with venetoclax and obinutuzumab in patients with newly diagnosed high-risk chronic lymphocytic leukemia or small lymphocytic lymphoma. Venetoclax may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Immunotherapy …

platelet count
corticosteroids
thrombocytopenia
monoclonal antibodies
hormone therapy
Rush - Copley Medical Center
 (5.9 away) Contact site
  • 0 views
  • 19 Sep, 2021
  • +384 other locations