Skokie, Illinois Clinical Trials

A listing of Skokie, Illinois clinical trials actively recruiting patient volunteers.

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Found 156 clinical trials
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Phase 2 Trial of MRTX849 in Combination with Pembrolizumab in Patients with Advanced Non-Small Cell Lung Cancer with KRAS G12C Mutation (KRYSTAL-7)

This Phase 2 study evaluates the clinical activity and safety of MRTX849 in combination with pembrolizumab in cohorts of patients with advanced NSCLC with KRAS G12C mutation and any PD-L1 TPS.

KRAS
pembrolizumab
USOR - Illinois Cancer Specialists - Niles
 (4.2 away) Contact site
  • 0 views
  • 28 Jul, 2021
  • +40 other locations
featured
A Randomized Phase 3 Study of Sitravatinib in Combination with Nivolumab Versus Docetaxel in Patients with Advanced Non-Squamous Non-Small Cell Lung Cancer with Disease Progression On or After Platinum-Based Chemotherapy and Checkpoint Inhibitor Therapy (SAPPHIRE)

This is an open-label, randomized (1:1), multicenter, Phase 3 clinical trial evaluating the safety and efficacy of nivolumab in combination with investigational agent sitravatinib compared to docetaxel in patients with advanced non-squamous NSCLC who have previously experienced radiographic disease progression on or after treatment with platinum-based chemotherapy in combination with …

cancer
cancer chemotherapy
squamous non-small cell lung cancer
lung cancer
non-squamous non-small cell lung cancer
Orchard Healthcare Research Inc
 (1.1 away) Contact site
  • 199 views
  • 28 Jul, 2021
  • +188 other locations
Safety Tolerability and Evidence of Activity Study of UBX1325 in Patients With Diabetic Macular Edema (DME)

This study is intended to assess the safety, tolerability and evidence of pharmacodynamic activity of a single intravitreal (IVT) injection of UBX1325 in patients with diabetic macular edema (DME)

Northwestern University
 (2.9 away) Contact site
  • 0 views
  • 26 Jul, 2021
  • +31 other locations
Study of Evobrutinib in Participants With RMS (evolutionRMS 2)

The study is to evaluate the efficacy and safety of evobrutinib administered orally twice daily versus Teriflunomide (Aubagio), administered orally once daily in participants with Relapsing Multiple Sclerosis (RMS).

aubagio
teriflunomide
evobrutinib
Research Site 715
 (2.6 away) Contact site
  • 0 views
  • 31 Jul, 2021
  • +258 other locations
Relapsing Forms of Multiple Sclerosis (RMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168)

Primary Objective: To assess efficacy of daily SAR442168 compared to a daily dose of 14 mg teriflunomide (Aubagio) measured by annualized adjudicated relapse rate (ARR) in participants with relapsing forms of MS Secondary Objective: To assess efficacy of SAR442168 compared to teriflunomide (Aubagio) on disability progression, MRI lesions, cognitive performance …

pregnancy test urine
brain lesion
aubagio
hmr1726
teriflunomide
Investigational Site Number 8400011
 (8.0 away) Contact site
  • 0 views
  • 20 Jul, 2021
  • +120 other locations
A Study of Benralizumab in Patients With Eosinophilic Esophagitis

The aim of this Phase 3 study is to investigate the use of benralizumab as a treatment for patients with EoE. The effect of doses of benralizumab on EoE histologic signs and symptoms will be assessed over a 52-week treatment period (including a 24-week double-blind placebo-controlled treatment period and a …

Research Site
 (6.0 away) Contact site
  • 0 views
  • 26 Jul, 2021
  • +83 other locations
Study of Evobrutinib in Participants With RMS (evolutionRMS 1)

The study is to evaluate the efficacy and safety of evobrutinib administered orally twice daily versus Teriflunomide (Aubagio), administered orally once daily in participants with Relapsing Multiple Sclerosis (RMS).

aubagio
teriflunomide
evobrutinib
Research Site 649
 (8.0 away) Contact site
  • 0 views
  • 30 Jul, 2021
  • +270 other locations
A Study of AKCEA-APOCIII-LRx Administered to Patients With Familial Chylomicronemia Syndrome (FCS)

The purpose of the study is to evaluate the efficacy of AKCEA-APOCIII-LRx as compared to placebo on the percent change in fasting triglycerides (TG) from baseline.

IONIS Investigative Site
 (2.6 away) Contact site
  • 0 views
  • 31 Jul, 2021
  • +28 other locations
Oral Islatravir (MK-8591) Once-Monthly as Preexposure Prophylaxis (PrEP) in Men and Transgender Women Who Have Sex With Men and Are at High Risk for HIV-1 Infection (MK-8591-024)

The main purpose of the study is to evaluate the efficacy and safety of oral Islatravir (ISL) once monthly (QM) as Preexposure Prophylaxis (PrEP) in cisgender men who have sex with men (MSM) and transgender women (TGW) who have sex with men and who are at high risk of HIV-1 …

Howard Brown Health Center ( Site 0004)
 (6.7 away) Contact site
  • 0 views
  • 01 Aug, 2021
  • +16 other locations
Study to Evaluate Adverse Events and Change in Disease Activity in Participants Between 18 to 75 Years of Age Treated With Subcutaneous (SC) Injections of ABBV-154 for Moderately to Severely Active Rheumatoid Arthritis (RA)

Rheumatoid Arthritis (RA) is an inflammatory disease of the joints causing pain, stiffness, swelling and loss of joint function. This study evaluates how safe and effective ABBV-154 is in participants treated for moderately to severely active RA. Adverse events and change in the disease activity will be assessed. ABBV-154 is …

stiffness
rheumatism
antirheumatics
methotrexate
Clinic of Robert Hozman/Clinical Investigation Specialists /ID# 228174
 (0.8 away) Contact site
  • 0 views
  • 01 Aug, 2021
  • +291 other locations