Rockford, Illinois Clinical Trials

A listing of Rockford, Illinois clinical trials actively recruiting patient volunteers.

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Found 20 clinical trials
T-DM1 and Tucatinib Compared With T-DM1 Alone in Preventing Relapses in People With High Risk HER2-Positive Breast Cancer the CompassHER2 RD Trial

This phase III trial studies how well trastuzumab emtansine (T-DM1) and tucatinib work in preventing breast cancer from coming back (relapsing) in patients with high risk, HER2 positive breast cancer. T-DM1 is a monoclonal antibody, called trastuzumab, linked to a chemotherapy drug, called DM1. Trastuzumab is a form of targeted …

OSF Saint Anthony Medical Center
 (3.8 away) Contact site
  • 0 views
  • 26 Jul, 2021
  • +762 other locations
Additional Support Program Via Text Messaging and Telephone-Based Counseling for Breast Cancer Patients Receiving Hormonal Therapy

This phase III trial compares an additional support program (text message reminders and/or telephone-based counseling) with usual care in making sure breast cancer patients take their endocrine therapy medication as prescribed (medication adherence). Medication adherence is how well patients take the medication as prescribed by their doctors, and good medical …

OSF Saint Anthony Medical Center
 (3.8 away) Contact site
  • 0 views
  • 27 Jul, 2021
  • +340 other locations
Hypofractionated Radiation Therapy After Mastectomy in Preventing Recurrence in Patients With Stage IIa-IIIa Breast Cancer

This randomized phase III trial studies how well hypofractionated radiation therapy works in preventing recurrence in patients with stage IIa-IIIa cancer who have undergone mastectomy. Hypofractionated radiation therapy delivers higher doses of radiation therapy over a shorter period of time and may kill more tumor cells that remain after surgery …

carcinoma
lobular carcinoma
ductal carcinoma in situ
mastectomy
human chorionic gonadotropin
SwedishAmerican Regional Cancer Center/ACT
 (5.9 away) Contact site
  • 335 views
  • 28 Jul, 2021
  • +911 other locations
PROACT Xa - A Trial to Determine if Participants With an On-X Aortic Valve Can be Maintained Safely on Apixaban

Currently, warfarin is the only approved anticoagulation for patients with mechanical valves. The purpose of this study is to determine if participants with an On-X Prosthetic Heart Valve / On-X aortic valve can be maintained safely and effectively on apixaban. Both the On-X aortic valve and apixaban have been approved …

aspirin
warfarin
apixaban 5 mg
OSF Cardiovascular Institute
 (2.5 away) Contact site
  • 79 views
  • 01 Aug, 2021
  • +74 other locations
Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)

This ALCHEMIST trial studies genetic testing in screening patients with stage IB-IIIA non-small cell lung cancer that has been or will be removed by surgery. Studying the genes in a patient's tumor cells may help doctors select the best treatment for patients that have certain genetic changes.

carcinoma
nivolumab
pemetrexed
tumor cells
carboplatin
SwedishAmerican Regional Cancer Center/ACT
 (5.9 away) Contact site
  • 1103 views
  • 01 Aug, 2021
  • +1138 other locations
Olanzapine With or Without Fosaprepitant Dimeglumine in Preventing Chemotherapy Induced Nausea and Vomiting in Cancer Patients Receiving Highly Emetogenic Chemotherapy

This randomized phase III trial studies how well olanzapine with or without fosaprepitant work in preventing chemotherapy induced nausea and vomiting in cancer patients receiving chemotherapy that causes vomiting. Olanzapine and fosaprepitant dimeglumine may help control nausea and vomiting in patients during chemotherapy. Olanzapine is usually given in combination with …

emetics
treatment regimen
cyclophosphamide
bilateral oophorectomy
primary cancer
OSF Saint Anthony Medical Center
 (3.8 away) Contact site
  • 109 views
  • 29 Jul, 2021
  • +603 other locations
Testing the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung Cancer

This phase III trial studies whether pembrolizumab alone as a first-line treatment, followed by pemetrexed and carboplatin with or without pembrolizumab after disease progression is superior to induction with pembrolizumab, pemetrexed and carboplatin followed by pembrolizumab and pemetrexed maintenance in treating patients with stage IV non-squamous non-small cell lung cancer. …

hepatitis c virus
carboplatin
cancer treatment
corticosteroid replacement therapy
squamous non-small cell lung carcinoma
SwedishAmerican Regional Cancer Center/ACT
 (5.6 away) Contact site
  • 206 views
  • 01 Aug, 2021
  • +831 other locations
Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer

The purpose of this study is to compare the effects on low risk breast cancer receiving usual care that includes regional radiation therapy, with receiving no regional radiation therapy. Researchers want to see if not giving this type of radiation treatment works as well at preventing breast cancer from coming …

carcinoma
sentinel lymph node biopsy
mastectomy
core needle biopsy
breast-conserving surgery
SwedishAmerican Regional Cancer Center/ACT
 (5.9 away) Contact site
  • 591 views
  • 25 Jul, 2021
  • +318 other locations
Testing the Addition of an Antibody to Standard Chemoradiation Followed by the Antibody for One Year to Standard Chemoradiation Followed by One Year of the Antibody in Patients With Unresectable Stage III Non-Small Cell Lung Cancer

This phase III trial studies how well an antibody (durvalumab) with chemotherapy and radiation therapy (chemoradiation) works in treating patients with stage III non-small cell lung cancer that cannot be removed by surgery (unresectable). Immunotherapy with monoclonal antibodies, such as durvalumab, may help the body's immune system attack the cancer, …

durvalumab
pemetrexed
tumor cells
carboplatin
measurable disease
SwedishAmerican Regional Cancer Center/ACT
 (5.9 away) Contact site
  • 136 views
  • 01 Aug, 2021
  • +583 other locations
De-intensified Radiation Therapy With Chemotherapy (Cisplatin) or Immunotherapy (Nivolumab) in Treating Patients With Early-Stage HPV-Positive Non-Smoking Associated Oropharyngeal Cancer

This phase II/III trial studies how well a reduced dose of radiation therapy works with nivolumab compared to cisplatin in treating patients with human papillomavirus (HPV)-positive oropharyngeal cancer that is early in its growth and may not have spread to other parts of the body (early-stage), and is not associated …

carcinoma
nivolumab
oropharyngeal cancer
dysphagia
metastasis
SwedishAmerican Regional Cancer Center/ACT
 (5.9 away) Contact site
  • 28 views
  • 01 Aug, 2021
  • +227 other locations