Princeton, Illinois Clinical Trials

A listing of Princeton, Illinois clinical trials actively recruiting patient volunteers.

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Found 104 clinical trials
Gemcitabine and Cisplatin Without Cystectomy for Patients With Muscle Invasive Bladder Urothelial Cancer and Select Genetic Alterations

This phase II trial studies how well gemcitabine hydrochloride and cisplatin work in treating participants with invasive bladder urothelial cancer. Drugs used in chemotherapy, such as gemcitabine hydrochloride and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from …

Illinois CancerCare-Princeton
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  • 40 views
  • 22 Aug, 2021
  • +383 other locations
Chemoradiotherapy With or Without Atezolizumab in Treating Patients With Localized Muscle Invasive Bladder Cancer

This phase III trial studies how well chemotherapy and radiation therapy work with or without atezolizumab in treating patients with localized muscle invasive bladder cancer. Radiation therapy uses high energy rays to kill tumor cells and shrink tumors. Chemotherapy drugs, such as gemcitabine, cisplatin, fluorouracil and mitomycin-C, work in different …

cancer
live vaccines
monoclonal antibody therapy
HIV Infection
atezolizumab
Illinois CancerCare-Princeton
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  • 37 views
  • 15 Sep, 2021
  • +182 other locations
Gemcitabine Hydrochloride and Cisplatin With or Without Nab-Paclitaxel in Treating Patients With Newly Diagnosed Advanced Biliary Tract Cancers

This phase III trial studies how well gemcitabine hydrochloride and cisplatin given with or without nab-paclitaxel work in treating patients with newly diagnosed biliary tract cancers that have spread to other places in the body. Drugs used in chemotherapy, such as gemcitabine hydrochloride, cisplatin, and nab-paclitaxel, work in different ways …

Illinois CancerCare-Princeton
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  • 263 views
  • 27 Jan, 2021
  • +717 other locations
Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

This phase II trial studies how well cabozantinib works in combination with nivolumab and ipilimumab in treating patients with rare genitourinary (GU) tumors that have spread to other places in the body. Cabozantinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. …

metastasis
brain metastases
hormone therapy
neutrophil count
squamous cell carcinoma
Illinois CancerCare-Princeton
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  • 191 views
  • 15 Sep, 2021
  • +476 other locations
Inotuzumab Ozogamicin and Blinatumomab in Treating Patients With Newly Diagnosed Recurrent or Refractory CD22-Positive B-Lineage Acute Lymphoblastic Leukemia

This phase II trial studies how well inotuzumab ozogamicin and blinatumomab work in treating patients with CD22-positive B-lineage acute lymphoblastic leukemia that is newly diagnosed, has come back, or does not respond to treatment. Immunotherapy with monoclonal antibodies, such as inotuzumab ozogamicin and blinatumomab, may help the body's immune system …

Illinois CancerCare-Princeton
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  • 5 views
  • 15 Sep, 2021
  • +220 other locations
Nivolumab and Ipilimumab in Treating Patients With Esophageal and Gastroesophageal Junction Adenocarcinoma Undergoing Surgery

This phase II/III trial studies the usefulness of treatment with nivolumab and ipilimumab in addition to standard of care chemotherapy and radiation therapy in patients with esophageal and gastroesophageal junction adenocarcinoma who are undergoing surgery. Immunotherapy with antibodies, such as nivolumab and ipilimumab, may remove the brake on the body's …

troponin
oophorectomy
carboplatin
neutrophil count
cancer
Illinois CancerCare-Princeton
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  • 11 views
  • 12 Sep, 2021
  • +288 other locations
Testing The Addition of a New Anti-cancer Drug Venetoclax to the Usual Treatment (Ibrutinib and Obinutuzumab) in Untreated Older Patients With Chronic Lymphocytic Leukemia

This phase III trial compares adding a new anti-cancer drug (venetoclax) to the usual treatment (ibrutinib plus obinutuzumab) in older patients with chronic lymphocytic leukemia who have not received previous treatment. The addition of venetoclax to the usual treatment might prevent chronic lymphocytic leukemia from returning. This trial also will …

rituximab
neutrophil count
cancer
ibrutinib
lymphoma
Illinois CancerCare-Princeton
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  • 382 views
  • 15 Sep, 2021
  • +740 other locations
Avelumab With or Without Cetuximab in Treating Patients With Advanced Skin Squamous Cell Cancer

This phase II trial studies how well avelumab with or without cetuximab work in treating patients with skin squamous cell cancer that has spread to other places in the body. Immunotherapy with monoclonal antibodies, such as avelumab and cetuximab, may help the body's immune system attack the cancer, and may …

neutrophil count
cancer
monoclonal antibodies
platelet count
serum pregnancy test
Illinois CancerCare-Princeton
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  • 30 views
  • 22 Aug, 2021
  • +410 other locations
Bupropion in Reducing Cancer Related Fatigue in Stage I-III Breast Cancer Survivors

This phase III trial studies how well bupropion works in reducing cancer related fatigue in stage I-III breast cancer survivors. Bupropion is a drug that is used to treat depression, as well as to help people quit smoking. Cancer and its treatment can cause fatigue. Giving bupropion may improve cancer …

bupropion
cancer
Illinois CancerCare-Princeton
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  • 171 views
  • 25 Jan, 2021
  • +167 other locations
A Comparison of Three Chemotherapy Regimens for the Treatment of Patients With Newly Diagnosed Mantle Cell Lymphoma

This phase II trial compares three chemotherapy regimens consisting of bendamustine, rituximab, high dose cytarabine, and acalabrutinib and studies how well they work in treating patients with newly diagnosed mantle cell lymphoma. Drugs used in chemotherapy, such as bendamustine and cytarabine, work in different ways to stop the growth of …

rituximab
gilbert's syndrome
neutrophil count
cancer
cytarabine
Illinois CancerCare-Princeton
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  • 26 views
  • 24 Jul, 2021
  • +305 other locations