Princeton, Illinois Clinical Trials

A listing of Princeton, Illinois clinical trials actively recruiting patient volunteers.

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Found 104 clinical trials
Gemcitabine and Cisplatin Without Cystectomy for Patients With Muscle Invasive Bladder Urothelial Cancer and Select Genetic Alterations

This phase II trial studies how well gemcitabine hydrochloride and cisplatin work in treating participants with invasive bladder urothelial cancer. Drugs used in chemotherapy, such as gemcitabine hydrochloride and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from …

Illinois CancerCare-Princeton
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  • 40 views
  • 22 Aug, 2021
  • +383 other locations
Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

This phase II trial studies how well cabozantinib works in combination with nivolumab and ipilimumab in treating patients with rare genitourinary (GU) tumors that have spread to other places in the body. Cabozantinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. …

growth factor
monoclonal antibodies
ovarian suppression
cabozantinib
corticosteroids
Illinois CancerCare-Princeton
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  • 191 views
  • 15 Sep, 2021
  • +476 other locations
Avelumab With or Without Cetuximab in Treating Patients With Advanced Skin Squamous Cell Cancer

This phase II trial studies how well avelumab with or without cetuximab work in treating patients with skin squamous cell cancer that has spread to other places in the body. Immunotherapy with monoclonal antibodies, such as avelumab and cetuximab, may help the body's immune system attack the cancer, and may …

monoclonal antibodies
cancer
cetuximab
neutrophil count
investigational drug
Illinois CancerCare-Princeton
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  • 30 views
  • 22 Aug, 2021
  • +410 other locations
Ramucirumab and Pembrolizumab Versus Standard of Care in Treating Patients With Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Non-Match Treatment Trial)

This phase II Lung-MAP non-Match treatment trial studies how well ramucirumab and pembrolizumab work versus standard of care in treating patients with non-small cell lung cancer that is stage IV or has come back. Immunotherapy with monoclonal antibodies, such as ramucirumab and pembrolizumab, may help the body's immune system attack …

cardiac disease
investigational drug
platinum-based chemotherapy
ct scan
measurable disease
Illinois CancerCare-Princeton
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  • 86 views
  • 25 Jan, 2021
  • +628 other locations
Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

This phase II trial studies how well radiation therapy with or without cisplatin works in treating patients with stage III-IVA squamous cell carcinoma of the head and neck who have undergone surgery. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. Drugs used in chemotherapy, such …

intensity-modulated radiation therapy
cancer
squamous cell carcinoma
caries
neutrophil count
Illinois CancerCare-Princeton
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  • 229 views
  • 24 Jan, 2021
  • +330 other locations
Low-Dose Ibuprofen in Improving Cognitive Impairment in Patients With Cancer

This randomized phase II trial studies how well low-dose ibuprofen in improving cognitive impairment in patients with cancer. Anti-inflammatory agents, such as ibuprofen, may slow the decline of cognitive processes and diseases involving the brain.

immunostimulants
primary cancer
cancer
Illinois CancerCare-Princeton
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  • 97 views
  • 15 Aug, 2021
  • +271 other locations
Pegylated Liposomal Doxorubicin Hydrochloride With Atezolizumab and/or Bevacizumab in Treating Patients With Recurrent Ovarian Fallopian Tube or Primary Peritoneal Cancer

This phase II/III trial studies how well pegylated liposomal doxorubicin hydrochloride with atezolizumab and/or bevacizumab work in treating patients with ovarian, fallopian tube, or primary peritoneal cancer that has come back (recurrent). Chemotherapy drugs, such as pegylated liposomal doxorubicin hydrochloride, work in different ways to stop the growth of tumor …

adenocarcinoma
ascites
monoclonal antibodies
primary peritoneal carcinoma
doxorubicin
Illinois CancerCare-Princeton
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  • 185 views
  • 16 Sep, 2021
  • +757 other locations
Abiraterone Acetate and Antiandrogen Therapy With or Without Cabazitaxel and Prednisone in Treating Patients With Metastatic Castration-Resistant Prostate Cancer Previously Treated With Docetaxel

This randomized phase II trial studies how well abiraterone acetate and antiandrogen therapy, with or without cabazitaxel and prednisone, work in treating patients with castration-resistant prostate cancer previously treated with docetaxel that has spread to other parts of the body. Androgens can cause the growth of prostate cancer cells. Hormone …

orchiectomy
adenocarcinoma
metastatic prostate cancer
flutamide
endocrine therapy
Illinois CancerCare-Princeton
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  • 1524 views
  • 11 May, 2021
  • +470 other locations
Gemcitabine Hydrochloride and Cisplatin With or Without Nab-Paclitaxel in Treating Patients With Newly Diagnosed Advanced Biliary Tract Cancers

This phase III trial studies how well gemcitabine hydrochloride and cisplatin given with or without nab-paclitaxel work in treating patients with newly diagnosed biliary tract cancers that have spread to other places in the body. Drugs used in chemotherapy, such as gemcitabine hydrochloride, cisplatin, and nab-paclitaxel, work in different ways …

Illinois CancerCare-Princeton
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  • 263 views
  • 27 Jan, 2021
  • +717 other locations
Testing The Addition of a New Anti-cancer Drug Venetoclax to the Usual Treatment (Ibrutinib and Obinutuzumab) in Untreated Older Patients With Chronic Lymphocytic Leukemia

This phase III trial compares adding a new anti-cancer drug (venetoclax) to the usual treatment (ibrutinib plus obinutuzumab) in older patients with chronic lymphocytic leukemia who have not received previous treatment. The addition of venetoclax to the usual treatment might prevent chronic lymphocytic leukemia from returning. This trial also will …

corticosteroids
immunoglobulin
venetoclax
lymphoma
flow cytometry
Illinois CancerCare-Princeton
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  • 382 views
  • 15 Sep, 2021
  • +740 other locations