Princeton, Illinois Clinical Trials

A listing of Princeton, Illinois clinical trials actively recruiting patient volunteers.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 105 clinical trials
Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors Lymphomas or Multiple Myeloma (The MATCH Screening Trial)

This phase II MATCH trial studies how well treatment that is directed by genetic testing works in patients with solid tumors or lymphomas that have progressed following at least one line of standard treatment or for which no agreed upon treatment approach exists. Genetic tests look at the unique genetic …

gonadotropin releasing hormone
carcinoma in situ
crizotinib
cytology specimen collection procedure
oophorectomy
Illinois CancerCare-Princeton
 (2.0 away) Contact site
  • 6097 views
  • 26 Sep, 2021
  • +1027 other locations
Platinum Based Chemotherapy or Capecitabine in Treating Patients With Residual Triple-Negative Basal-Like Breast Cancer Following Neoadjuvant Chemotherapy

This randomized phase III trial studies how well cisplatin or carboplatin (platinum based chemotherapy) works compared to capecitabine in treating patients with remaining (residual) basal-like triple-negative breast cancer following chemotherapy after surgery (neoadjuvant). Drugs used in chemotherapy, such as cisplatin, carboplatin and capecitabine, work in different ways to stop the …

axillary lymph node dissection
carcinoma in situ
triple-negative breast cancer
lobular carcinoma in situ
oophorectomy
Illinois CancerCare-Princeton
 (2.0 away) Contact site
  • 513 views
  • 24 Jan, 2021
  • +702 other locations
Testing the Drug Atezolizumab or Placebo With Usual Therapy in First-Line HER2-Positive Metastatic Breast Cancer

This randomized phase III trial studies how well paclitaxel, trastuzumab, and pertuzumab with or without atezolizumab works in treating patients with breast cancer that has spread to other parts of the body (metastatic). Chemotherapy drugs, such as paclitaxel, work in different ways to stop the growth of tumor cells, either …

adenocarcinoma of the breast
HER2
breast cancer
monoclonal antibodies
ct scan
Illinois CancerCare-Princeton
 (2.0 away) Contact site
  • 445 views
  • 26 Sep, 2021
  • +464 other locations
Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma the EQUATE Trial

This phase III trial compares the combination of four drugs (daratumumab, bortezomib, lenalidomide and dexamethasone) to the use of a three drug combination (daratumumab, lenalidomide and dexamethasone). Bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Chemotherapy drugs, such as lenalidomide, …

plasmacytosis
hypertension
lenalidomide
neutrophil count
cancer
Illinois CancerCare-Princeton
 (2.0 away) Contact site
  • 0 views
  • 22 Sep, 2021
  • +373 other locations
T-DM1 and Tucatinib Compared With T-DM1 Alone in Preventing Relapses in People With High Risk HER2-Positive Breast Cancer the CompassHER2 RD Trial

This phase III trial studies how well trastuzumab emtansine (T-DM1) and tucatinib work in preventing breast cancer from coming back (relapsing) in patients with high risk, HER2 positive breast cancer. T-DM1 is a monoclonal antibody, called trastuzumab, linked to a chemotherapy drug, called DM1. Trastuzumab is a form of targeted …

Illinois CancerCare-Princeton
 (2.0 away) Contact site
  • 0 views
  • 22 Aug, 2021
  • +816 other locations
Trying to Find the Correct Length of Treatment With Immune Checkpoint Therapy

This phase III trial compares survival in urothelial cancer patients who stop immune checkpoint inhibitor treatment after being treated for about a year to those patients who continue treatment with immune checkpoint inhibitors. Immunotherapy with monoclonal antibodies, such as avelumab, durvalumab, pembrolizumab, atezolizumab, and nivolumab, may help the body's immune …

Illinois CancerCare-Princeton
 (2.0 away) Contact site
  • 0 views
  • 22 Aug, 2021
  • +283 other locations
Additional Support Program Via Text Messaging and Telephone-Based Counseling for Breast Cancer Patients Receiving Hormonal Therapy

This phase III trial compares an additional support program (text message reminders and/or telephone-based counseling) with usual care in making sure breast cancer patients take their endocrine therapy medication as prescribed (medication adherence). Medication adherence is how well patients take the medication as prescribed by their doctors, and good medical …

Illinois CancerCare-Princeton
 (2.0 away) Contact site
  • 6 views
  • 12 Sep, 2021
  • +368 other locations
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer ALCHEMIST Chemo-IO Study

This phase III ALCHEMIST trial compares the addition of pembrolizumab to usual chemotherapy versus usual chemotherapy for the treatment of stage IIA, IIB IIIA or IIIB non-small cell lung cancer that has been removed by surgery. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack …

carcinoma
platelet count
pemetrexed
pembrolizumab
carboplatin
Illinois CancerCare-Peru
 (17.6 away) Contact site
  • 136 views
  • 28 Sep, 2021
  • +814 other locations
Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

This phase III trial studies combination chemotherapy and atezolizumab to see how well it works compared with combination chemotherapy alone in treating patients with stage III colon cancer and deficient deoxyribonucleic acid (DNA) mismatch repair. Drugs used in combination chemotherapy, such as oxaliplatin, leucovorin calcium, and fluorouracil, work in different …

immunosuppressive
antibiotics
monoclonal antibodies
hysterectomy
combination chemotherapy
Illinois CancerCare-Princeton
 (2.0 away) Contact site
  • 1047 views
  • 26 Sep, 2021
  • +595 other locations
S0820 Adenoma and Second Primary Prevention Trial

The investigators hypothesize that the combination of eflornithine and sulindac will be effective in reducing a three-year event rate of adenomas and second primary colorectal cancers in patients previously treated for Stages 0 through III colon or rectal cancer.

rectal carcinoma
anticoagulants
unstable angina
aspirin
adenoma
Illinois CancerCare-Princeton
 (2.0 away) Contact site
  • 2518 views
  • 03 Mar, 2021
  • +1033 other locations