Ottawa, Illinois Clinical Trials

A listing of Ottawa, Illinois clinical trials actively recruiting patient volunteers.

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Found 109 clinical trials
Radiation Therapy With Concomitant and Adjuvant Temozolomide Versus Radiation Therapy With Adjuvant PCV Chemotherapy in Patients With Anaplastic Glioma or Low Grade Glioma

Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. It is not yet known whether giving radiation with concomitant and adjuvant …

Illinois CancerCare-Peru
 (14.8 away) Contact site
  • 167 views
  • 28 Jul, 2021
  • +125 other locations
Testing the Addition of Ruxolitinib to the Usual Treatment (Tyrosine Kinase Inhibitors) for Chronic Myeloid Leukemia

This randomized phase II trial studies how well ruxolitinib phosphate, and bosutnib, dasatinib, or nilotinib, work in treating patients with chronic myeloid leukemia. Chronic myeloid leukemia cells produce a protein called BCR-ABL. The BCR-ABL protein helps chronic myeloid leukemia cells to grow and divide. Tyrosine kinase inhibitors, such as bosutinib, …

Illinois CancerCare-Ottawa Clinic
 (0.5 away) Contact site
  • 38 views
  • 11 May, 2021
  • +441 other locations
Vitamin D3 With Chemotherapy and Bevacizumab in Treating Patients With Advanced or Metastatic Colorectal Cancer

This phase III trial studies how well vitamin D3 given with standard chemotherapy and bevacizumab works in treating patients with colorectal cancer that has spread to other parts of the body. Vitamin D3 helps the body use calcium and phosphorus to make strong bones and teeth. Drugs used in chemotherapy, …

platelet count
fluorouracil
irinotecan
hydrochlorothiazide
liver metastasis
Illinois CancerCare-Ottawa Clinic
 (0.5 away) Contact site
  • 65 views
  • 27 Jul, 2021
  • +978 other locations
Trying to Find the Correct Length of Treatment With Immune Checkpoint Therapy

This phase III trial compares survival in urothelial cancer patients who stop immune checkpoint inhibitor treatment after being treated for about a year to those patients who continue treatment with immune checkpoint inhibitors. Immunotherapy with monoclonal antibodies, such as avelumab, durvalumab, pembrolizumab, atezolizumab, and nivolumab, may help the body's immune …

Illinois CancerCare-Ottawa Clinic
 (0.5 away) Contact site
  • 0 views
  • 30 Jul, 2021
  • +282 other locations
Additional Support Program Via Text Messaging and Telephone-Based Counseling for Breast Cancer Patients Receiving Hormonal Therapy

This phase III trial compares an additional support program (text message reminders and/or telephone-based counseling) with usual care in making sure breast cancer patients take their endocrine therapy medication as prescribed (medication adherence). Medication adherence is how well patients take the medication as prescribed by their doctors, and good medical …

Illinois CancerCare-Ottawa Clinic
 (0.5 away) Contact site
  • 0 views
  • 27 Jul, 2021
  • +340 other locations
Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma the EQUATE Trial

This phase III trial compares the combination of four drugs (daratumumab, bortezomib, lenalidomide and dexamethasone) to the use of a three drug combination (daratumumab, lenalidomide and dexamethasone). Bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Chemotherapy drugs, such as lenalidomide, …

platelet count
hypertension
neutrophil count
measurable disease
daratumumab
Illinois CancerCare-Ottawa Clinic
 (0.5 away) Contact site
  • 0 views
  • 21 Jul, 2021
  • +365 other locations
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer ALCHEMIST Chemo-IO Study

This phase III ALCHEMIST trial compares the addition of pembrolizumab to usual chemotherapy versus usual chemotherapy for the treatment of stage IB, II, or IIIA non-small cell lung cancer that has been removed by surgery. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the …

platelet count
pembrolizumab
carboplatin
paclitaxel
carcinoma
Illinois CancerCare-Peru
 (14.8 away) Contact site
  • 136 views
  • 01 Aug, 2021
  • +808 other locations
Testing the Addition of the Drugs Apalutamide and Abiraterone Acetate With Prednisone to the Usual Hormone Therapy and Radiation Therapy After Surgery for Prostate Cancer

This phase III trial studies how well adding apalutamide, abiraterone acetate, and prednisone to the usual hormone therapy and radiation therapy works compared to the usual hormone therapy and radiation therapy in treating patients with node-positive prostate cancer after surgery. Radiation therapy uses high energy x-ray to kill tumor cells …

platelet count
apalutamide
tumor cells
androgens
prostatectomy
Illinois CancerCare-Ottawa Clinic
 (0.5 away) Contact site
  • 72 views
  • 09 Jun, 2021
  • +113 other locations
Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer

This phase II/III trials studies whether maintenance immunotherapy (nivolumab) following definitive treatment with radiation and chemotherapy (cisplatin) result in significant improvement in overall survival (time being alive) and progression-free survival (time being alive without cancer) for patients with intermediate risk human papillomavirus (HPV) positive oropharynx cancer (throat cancer) that has …

Illinois CancerCare-Ottawa Clinic
 (0.5 away) Contact site
  • 135 views
  • 01 Aug, 2021
  • +539 other locations
De-intensified Radiation Therapy With Chemotherapy (Cisplatin) or Immunotherapy (Nivolumab) in Treating Patients With Early-Stage HPV-Positive Non-Smoking Associated Oropharyngeal Cancer

This phase II/III trial studies how well a reduced dose of radiation therapy works with nivolumab compared to cisplatin in treating patients with human papillomavirus (HPV)-positive oropharyngeal cancer that is early in its growth and may not have spread to other parts of the body (early-stage), and is not associated …

tonsillectomy
head and neck cancer
carcinoma
hepatitis b virus surface antigen
cavities
Illinois CancerCare-Ottawa Clinic
 (0.5 away) Contact site
  • 28 views
  • 01 Aug, 2021
  • +227 other locations