Oakbrook Terrace, Illinois Clinical Trials

A listing of Oakbrook Terrace, Illinois clinical trials actively recruiting patient volunteers.

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Found 102 clinical trials
Study on Olaparib Plus Abiraterone as First-line Therapy in Men With Metastatic Castration-resistant Prostate Cancer

The purpose of this study is to evaluate the efficacy and safety (including evaluating side effects) of combination of olaparib and abiraterone versus placebo and abiraterone in patients with metastatic castration-resistant prostate cancer (mCRPC) who have received no prior cytotoxic chemotherapy or new hormonal agents (NHAs) at metastatic castration-resistant prostate …

androgen suppression
abiraterone
androgen
MRI
olaparib
Research Site
 (7.7 away) Contact site
  • 200 views
  • 23 Jul, 2021
  • +194 other locations
Trial of Andexanet in ICH Patients Receiving an Oral FXa Inhibitor

Randomized, controlled clinical trial evaluating the efficacy and safety of andexanet versus usual standard of care in patients with intracranial hemorrhage anticoagulated with a direct oral anticoagulant

Loyola University Medical Center
 (6.5 away) Contact site
  • 19 views
  • 17 Jul, 2021
  • +180 other locations
LUMINA Phase III Study Assessing the Efficacy and Safety of Intravitreal Injections of 440 ug DE-109 Sirolimus for the Treatment of Active Non-Infectious Uveitis of the Posterior Segment of the Eye

This is a Phase III study to assess the efficacy and safety of DE-109 440 g every 2 months in subjects with active, non-infectious uveitis of the posterior segment of the eye (NIU-PS). There is a 6-month, single-arm, open-label period after completion of the 6-month doublemasked, controlled period allows the …

Illinois Retina Associate
 (9.2 away) Contact site
  • 126 views
  • 09 Jul, 2021
  • +89 other locations
The Orchestra Study: An 18-month Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of Oral UCB0599 in Study Participants With Early-stage Parkinson's Disease

The Orchestra Study (study number PD0053) is a clinical research study for people with early-stage Parkinson’s disease (<2 years). The aim of the study is to find out whether an investigational medication known as UCB0599 can slow the progression of Parkinson’s disease and whether it is efficacious and well tolerated (which means …

dopamine
tremor
movement disorder
bradykinesia
motor symptoms
Northwestern Memorial Healthcare - Office of Research
 (9.8 away) Contact site
  • 0 views
  • 15 Jul, 2021
  • +22 other locations
Immune Modulators for Treating COVID-19

ACTIV-1 IM is a master protocol designed to evaluate multiple investigational agents for the treatment of moderately or severely ill patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The research objectives are to evaluate each agent with respect to speed of recovery, mortality, illness severity, and hospital resource …

Loyola University Medical Center
 (6.5 away) Contact site
  • 0 views
  • 11 Jul, 2021
  • +84 other locations
Study of Efficacy and Safety of Brolucizumab Versus Panretinal Photocoagulation Laser in Patients With Proliferative Diabetic Retinopathy

The purpose of this study is to evaluate the efficacy and safety of brolucizumab compared to panretinal photocoagulation laser (PRP) in patients with proliferative diabetic retinopathy (PDR). This evaluation will provide information that brolucizumab is non-inferior to PRP with respect to the change in best corrected visual acuity at Week …

Novartis Investigative Site
 (3.0 away) Contact site
  • 0 views
  • 21 Jul, 2021
  • +69 other locations
Study to Evaluate the Efficacy of Brexucabtagene Autoleucel (KTE-X19) in Participants With Relapsed/Refractory Mantle Cell Lymphoma (Cohort 3)

The primary objective is to evaluate the efficacy of brexucabtagene autoleucel (KTE-X19) in participants with relapsed/refractory (r/r) mantle cell lymphoma (MCL) in Cohort 3 of this study.

Loyola University
 (6.5 away) Contact site
  • 0 views
  • 21 Jul, 2021
  • +30 other locations
A Study to Evaluate the Efficacy and Safety of Efgartigimod PH20 Subcutaneous in Adult Patients With Primary Immune Thrombocytopenia

This is a phase 3, multicenter, randomized, double-blinded, placebo-controlled, parallel-group trial to evaluate the efficacy, safety, and effect on QoL/PRO of efgartigimod PH20 SC treatment in adult patients with primary ITP.

Investigator Site 0010079
 (8.1 away) Contact site
  • 0 views
  • 09 Jul, 2021
  • +20 other locations
ACTIV-3b: Therapeutics for Severely Ill Inpatients With COVID-19

This study looks at the safety and effectiveness of different drugs in treating COVID-19 in people who have been hospitalized with the infection and who have acute respiratory failure. Participants in the study will be treated with either a study drug plus current standard of care (SOC), or with placebo …

Edward Hines VA Hospital (Site 074-012), 5000 S. 5th Ave.
 (6.6 away) Contact site
  • 0 views
  • 22 Jul, 2021
  • +34 other locations
National Adaptive Trial for PTSD Related Insomnia

Many Veterans with posttraumatic stress disorder (PTSD) have trouble sleeping or have frequent nightmares. So far, no medication has been approved for treatment of insomnia in PTSD. The purpose of this research study is to find out if taking medications called trazodone, eszopiclone, or gabapentin can help decrease symptoms of …

behavior therapy
poor sleep
nightmares
depression
anxiety
Edward Hines Jr. VA Hospital, Hines, IL
 (6.6 away) Contact site
  • 0 views
  • 14 Jul, 2021
  • +34 other locations