Oak Lawn, Illinois Clinical Trials

A listing of Oak Lawn, Illinois clinical trials actively recruiting patient volunteers.

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Found 13 clinical trials
A Study to Learn if Recombinant Human Parathyroid Hormone [rhPTH(1-84)] Can Improve Symptoms and Metabolic Control in Adults With Hypoparathyroidism (BALANCE)

Recombinant human parathyroid hormone, also known as if rhPTH(1-84), is a medicine to treat people with Hypothyroidism. The main aim of this study is to learn if rhPTH(1-84) can improve symptoms in adults with hypoparathyroidism. In this study, participants will receive 1 of 2 treatments: rhPTH(1-84) or a placebo. A …

thyroid-stimulating hormone
serum parathyroid hormone
25-hydroxyvitamin d
University of Chicago
 (8.8 away) Contact site
  • 03 Feb, 2021
  • +49 other locations
Phase 4 Study of Obeticholic Acid Evaluating Clinical Outcomes in Patients With Primary Biliary Cholangitis

Primary Biliary Cholangitis (PBC) is a serious, life-threatening, bile acid related liver disease of unknown cause. Without treatment, it frequently progresses to liver fibrosis and eventual cirrhosis requiring liver transplantation or resulting in death. The investigational drug, Obeticholic Acid (OCA) is a modified bile acid and FXR agonist that is …

liver disease
antimitochondrial antibody
immune globulin
bile acid
Northwestern University Feinberg School of Medicine
 (8.8 away) Contact site
  • 27 May, 2021
  • +322 other locations
Vasoactive Drugs in Intensive Care Unit

The investigators hypothesis is that for ICU patients with shock, the use of the vasoactive drugs phenylephrine and vasopressin will reduce tachydysrhythmias when compared to norepinephrine and epinephrine. To investigate this hypothesis, the investigators are conducting a randomized double blind controlled trial comparing phenylephrine and vasopressin vs. norepinephrine and epinephrine …

urine output
University of Chicago Medical Center
 (8.8 away) Contact site
  • 26 Jan, 2021
  • 1 location
Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

PREVENTABLE is a multi-center, randomized, parallel group, placebo-controlled superiority study. Participants will be randomized 1:1 to atorvastatin 40 mg or placebo. This large study conducted in community-dwelling older adults without cardiovascular disease (CVD) or dementia will demonstrate the benefit of statins for reducing the primary composite of death, dementia, and …

mild cognitive impairment
hmg-coa reductase inhibitor
primary prevention
University of Chicago
 (8.8 away) Contact site
  • 26 Mar, 2021
  • +86 other locations
Durvalumab Long-Term Safety and Efficacy Study

The aims of the study are to monitor the long-term safety of durvalumab, to provide continued treatment or retreatment with durvalumab to eligible patients, and to collect overall survival (OS) information.

cancer treatment
Research Site
 (8.8 away) Contact site
  • 13 Jun, 2021
  • +164 other locations
Trial of Parkinson's And Zoledronic Acid

This home-based study is a randomized (1:1) placebo-controlled trial of a single infusion of zoledronic acid-5 mg (ZA) for the prevention of fractures in men and women aged 60 years and older with Parkinson's disease and parkinsonism with at least 2 years of follow-up. A total of 3500 participants will …

vascular parkinsonism
zoledronic acid
parkinson's disease
University of Chicago
 (8.8 away) Contact site
  • 05 Feb, 2021
  • +32 other locations
Study to Assess Efficacy and Safety of SZC for the Management of High Potassium in Patients With Symptomatic HFrEF Receiving Spironolactone

The main objective of this study is to evaluate the efficacy of SZC as compared with placebo in keeping potassium levels within the normal range (3.5-5.0 mEq/L) while on spironolactone 25 mg daily without assistance of rescue therapy for hyperkalaemia (HK).

Research Site
 (8.8 away) Contact site
  • 24 May, 2021
  • +36 other locations
Impact of Suvorexant on Sympathetic Nerve Activity and Baroreflex Function in Chronic Insomnia

This study aims to evaluate the effect of Suvorexant on sympathetic nerve activity and baroreflex function in subject with chronic insomnia. The investigator's central hypothesis is that Suvorexant will reduce sympathetic nerve activity and improve baroreflex function when compared to placebo.

body mass index
chronic insomnia
University of Chicago
 (8.8 away) Contact site
  • 26 Jan, 2021
  • +2 other locations
Effect of Farxiga on Renal Function and Size in Type 2 Diabetic Patients With Hyperfiltration

The investigators propose to treat newly diagnosed, hyperfiltering T2DM patients with or without microalbuminuria with dapagliflozin or metformin for 4 months. The metformin-treated group will serve as controls for improved glycemic control, since the investigators have shown that insulin therapy to normalize A1c reduces hyperfiltration and kidney size in T1DM …

The University of Chicago
 (8.8 away) Contact site
  • 16 May, 2021
  • +5 other locations
Pharmacogenetic Study of Antiarrhythmic Drugs for Atrial Fibrillation

In this pilot and feasibility study, the investigators will enroll patients with frequent symptomatic episodes of atrial fibrillation (AF) in a cross-over study testing two different classes of anti arrhythmic drugs (AADs). This pilot and feasibility study will provide preliminary data for a larger study in which the investigators will …

antiarrhythmic drug
Advocate Christ Medical Center
 (0.4 away) Contact site
  • 29 Apr, 2021
  • +3 other locations